clinical trial of nicardipine prolonged release implants for preventing cerebral vasospasm multicenter cooperative s
Báo cáo hóa học: " Phase I clinical trial of the vaccination for the patients with metastatic melanoma using gp100derived epitope peptide " pot
... assay in some patients (P5 and P6) suggest the existence of the mechanisms to suppress the immune functions In these patients, the dextramer-positive CTLs were observed, but the ELISPOT assays ... in the presence of feeder cells to establish gp100-specific CTL clones Six clones were established (1 clone for P2, clones for P3, and clones for P4) A standard h 51Cr -release assay was employed ... enrolled patients Patients Age Sex Primary sites Sites of metastases Stage PS P1 41 female Skin (back) Liver, Spleen, Skin IV Previous Tx S/ C P2 74 female Skin (knee) Lymph nodes IV S/ C P3 58 male...
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Báo cáo y học: "Initial clinical trial of epratuzumab (humanized anti-CD22 antibody) for immunotherapy of systemic lupus erythematosu" ppt
... rules Results Statistical analyses The primary assessment of disease activity compared posttreatment BILAG results with those at study entry, using total BILAG scores for overall assessment and ... to assess the statistical significance of changes in total BILAG scores compared to their baseline values All statistical tests used a significance level of 0.05 Page of 11 (page number not for ... effects for some systems, such as Blevel disease in the neurological and renal systems, and only one case of lymphopenia in the hematological system showed improvement In spite of small numbers,...
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Báo cáo y học: "Early response predicts subsequent response to olanzapine long-acting injection in a randomized, double-blind clinical trial of treatment for schizophrenia" potx
... change in Davis Factor PANSS subscale scores for Responder Groups Abbreviations: LS = least square; PANSS = Positive and Negative Syndrome Scale Score a Early response was defined as a ≥30% improvement ... this analysis may have been due to use of a later time point to assess early response; Week for this analysis versus Week in the oral olanzapine studies Predictions of later response have been shown ... in studies of oral antipsychotics, including analyses of patients with chronic schizophrenia,[7] of patients with first-episode psychosis,[9] of a prospective study of patients with chronic schizophrenia,[7]...
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báo cáo khoa học:"The WRITTEN-HEART study (expressive writing for heart healing): rationale and design of a randomized controlled clinical trial of expressive writing in coronary patients referred to residential cardiac rehabilitation" docx
... (BAI) is a measure of anxiety symptoms It consists of 21 items that represent 21 psychological or somatic symptoms of anxiety (such as numbness, hot and cold sweats or feelings of dread) The respondent ... is a moderator of the expressive writing effects This hypothesis was guided by social constraint theory, which suggests that the absence of social outlets for emotional expression and processing ... awareness of the benefits of adverse events and circumstances is an important predictor of successful adjustment [30-32] Further empirical support to the rationale of this study comes from the results...
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Clinical Management of Rape Survivors Developing protocols for use with refugees and internally displaced persons pdf
... transporting swabs sheet for collecting debris as the survivor undresses measure for measuring the size of bruises, lacerations, etc* Paper bags for collection of evidence* Paper tape for sealing ... kits Before you start your service, make sure the staff are aware of the indications for PEP and how to counsel survivors on this issue or make a list of names and addresses of providers for ... pregnancy Take note of the pubertal stage Look for signs that are consistent with the survivor 's story, such as bite and punch marks, marks of restraints on the wrists, patches of hair missing from the...
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Báo cáo y học: "Clinical use of a modified release methylphenidate in the treatment of childhood attention deficit hyperactivity disorder" pps
... health, education and social services professionals was held to address patient 4 s needs She was reassessed by the doctor and diagnosed with ADHD, comorbid oppositional defiant disorder and additional ... symptoms was requested following increasing concerns regarding his behaviour at home and at school The assessments consisted of a diagnostic interview by clinicians and a screening of the information ... in school and this caused significant difficulties for her parents, whose work life was constantly disrupted by calls from the school Patient 3 s parents had her referred for further assessment...
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Báo cáo khoa học: "Long-term results from a randomized phase II trial of neoadjuvant combined-modality therapy for locally advanced rectal cancer" ppt
... to estimate the rates for disease specific mortality, local recurrence and distant metastasis Figure Distribution of patients through the trial Page of Statistical analysis was performed using ... the SPSS statistical software package, version 12 (SPSS Inc., Chicago, IL, USA) Results Patients’ baseline characteristics Between June 2004 and January 2005, 57 patients entered the study The study ... possible side effects, and signed an informed consent The trial was approved by the ethic committees of the Institute of Oncology, Ljubljana, Slovenia and of the Republic of Slovenia and was...
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báo cáo khoa học:" Study on the clinical application of pulsed DC magnetic technology for tracking of intraoperative head motion during frameless stereotaxy" pdf
... statistical analyses were performed using the SPSS 13.0 for Windows® software package Results Patients and indications for frameless stereotaxy The clinical study included 40 patients with intracerebral ... treatment of brain tumors J Neurosurg 2000, 93:208-213 Suess O, Schönherr S, Schilling A, Kühn B, Mularski SO, Suess S, Brock M, Kombos Th: [Sensor-based detection of skull positioning for image-guided ... performed under standard conditions and without additional use of the DRF The patients of this group served as controls Type B consisted of two subgroups The first subgroup included those cases...
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Báo cáo y học: "A multicenter, double-blind, randomized, controlled phase III clinical trial of chicken type II collagen in rheumatoid arthritis" ppsx
... active suppression of low-dose oral tolerance can also suppress an unrelated immune response (bystander suppression), paving the way for therapy of autoimmune diseases [35] The results from human clinical ... adjuvant such as mannitol and glidantin Figure shows the flow sheet of production of CCII Clinical assessments Clinical assessments of efficacy were made at baseline and repeated 12 and 24 weeks later ... blood cell count, serum levels of liver enzymes, creatinine, uric acid, and urinalysis Statistical analysis Safety assessments were performed on all patients who consumed any masked study medication...
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Báo cáo khoa học: "Stratification, Blinding and Placebo Effect in a Randomized, Double Blind Placebo-controlled Clinical Trial of Gold Bead Implantation in Dogs with Hip Dysplasia" doc
... characteristics and diagnosis of disease Although methods of statistical analysis exist to compensate for unequal treatment groups, it is more convincing to present data from equivalent groups, and stratification ... was confirmed with multiple regression analysis, with best improvement in pain signs in dogs less than 2.5 years of age This analysis also revealed that dogs older than six years had an increased ... ods, good methodological studies of factors influencing treatment outcome are lacking During statistical analysis of treatment results, it is highly desirable to have as equal groups as possible...
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Báo cáo khoa học: "Clinical trial of a weaning protocol" potx
... numbers of physicians (six residents, two postdoctoral fellows, and two attending physicians for a 14-bed unit), and used a structured standard checklist to make patient review during rounds more systematic ... be necessary if other systems improvement elements are in place [1] Their conclusion seems consistent with the study data and with previous publications An alternate conclusion is also supported ... Haynes R, Hanna S, Smith K: Effects of computerbased clinical decision support systems on physician performance and patient outcomes: a systematic review JAMA 1998, 280:1339-1346 18 Morris A:...
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Báo cáo y học: "Randomised controlled trial of school-based humanistic counselling for emotional distress in young people: Feasibility study and preliminary indications of efficacy" pot
... with five items (scored from to 2) assessing levels of physical symptoms, worry, unhappiness, nervousness and fears It was used as the primary outcome measure for this study as it has been found ... (Cronbach 's α = 76) The prosocial subscale of the SDQ (SDQ-PS) consists of the remaining five SDQ items, and assesses the young person 's perception of themselves as kind and helpful to others Inter-item ... as well as to complete an 'Impact Supplement' assessing overall distress and impairment in different life domains The emotional symptoms subscale of the SDQ (SDQES) measures emotional distress,...
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Báo cáo y học: " Randomized clinical trial of bedside ultrasound among patients with abdominal pain in the emergency " doc
... proportions between the groups All analyses were performed according to intention-to-treat The results were regarded as significant if p was less than 0.05, two-tailed SPSS 14.0 was used for statistical ... first randomized study assessing patient satisfaction and the long-term effects as regards health care consumption when using US for diagnosis of abdominal pain at the ED We found a small, but still ... basis In a previous study we showed that the number of subsequent US examinations were less if the patients had been examined with surgeon-performed US at the ED [10] In this study we have studied...
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Báo cáo hóa học: " Effectiveness of a Wii balance board-based system (eBaViR) for balance rehabilitation: a pilot randomized clinical trial in patients with acquired brain injury" ppt
... metropolitan hospital Each patient participated in a total of 20 one-hour-sessions of rehabilitation and accomplished a minimum of sessions and a maximum of sessions per week During control sessions, traditional ... no adverse symptoms were described by therapists Discussion Balance difficulties are amongst the most frequent motor disorders of ABI patients [39-41] The recovery of this skill is an essential ... groups improved in the same way These results support the hypothesis that the system promotes the recovery of static balance, in which the system focuses on its exercises, while it has no significant...
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Báo cáo hóa học: " In Situ Loading of Basic Fibroblast Growth Factor Within Porous Silica Nanoparticles for a Prolonged Release" ppt
... the assay reagent is composed of two fluorogenic peptide substrates (GF-AFC, live-cell protease substrate and bis-AAF-R110, dead-cell protease substrate) to the assay buffer This reagent was added ... an emission of 520 nm, respectively Results and Discussion Basic FGF encapsulated in MSNs in situ has been developed by a water-in-oil microemulsion The volume of 123 1300 Nanoscale Res Lett ... 2a shows the SEM micrograph of the bFGF-loaded MSNs that are spherical The average particle size (d) of the SiO2 NPs was 57 ± nm, which is smaller than most of polymer nano-containers It is also...
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Báo cáo y học: "Progesterone - new therapy in mild carpal tunnel syndrome? Study design of a randomized clinical trial for local therapy" pptx
... intermittent symptoms can cause permanent loss of sensation and partial paralysis in abduction and opposition of the thumb, whereas severe CTS can cause permanent loss of sensation and paralysis in abduction ... consensus criteria of classification of the CTS Only "classic/probable" and "possible" cases will be enrolled [47,48] Then only patients with "mild" CTS will be successively included in the trial ... Endoscopic versus open carpal tunnel release J Hand Surg Am 2009, 34:535-539 10 Vasiliadis HS, Xenakis TA, Mitsionis G, Paschos N, Georgoulis A: Endoscopic versus open carpal tunnel release Arthroscopy...
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Báo cáo y học: " Treatment of forefoot problems in older people: study protocol for a randomised clinical trial comparing podiatric treatment to standardised shoe advi" potx
... the shoes they wear most often for this assessment and for the pressure measurements Next, the Foot Posture Index will be assessed and scored according to Redmond et al [19] To assess pressure ... influence of ill-fitting shoes [14,15] Some evidence exists that ill-fitting footwear is associated with foot problems such as corns, calluses, hallux valgus and lesser toe deformities Both the ... cases, a significance level of 5% is pre-stipulated Discussion In this paper we have described the design of a randomised clinical trial to compare the effects of two common treatments for forefoot...
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Báo cáo y học: "Using theories of behaviour to understand transfusion prescribing in three clinical contexts in two countries: Development work for an implementation trial" pps
... cells) and its possible predictors, the questionnaire will include questions with multi-item scales to assess elements of the identified psychological theories Responses will be elicited using ... constructs) and three outcome measures (strength of intention, direct estimation of intention, and simulated behaviour) These relationships will be assessed using multiple regression analysis Sample size ... intervention Most were single-centre studies, and many were performed more than 10 years ago The universal success in the published studies raises the possibility of publication bias These concerns about...
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báo cáo khoa học: " Using theories of behaviour to understand transfusion prescribing in three clinical contexts in two countries: Development work for an implementation trial" pptx
... cells) and its possible predictors, the questionnaire will include questions with multi-item scales to assess elements of the identified psychological theories Responses will be elicited using ... constructs) and three outcome measures (strength of intention, direct estimation of intention, and simulated behaviour) These relationships will be assessed using multiple regression analysis Sample size ... intervention Most were single-centre studies, and many were performed more than 10 years ago The universal success in the published studies raises the possibility of publication bias These concerns about...
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