changes in approved project leadership or the replacement or reassignment of other key project personnel shall be requested by the grantee and approved in writing by the ado prior to effecting such changes
Measuring Changes in Service Costs to Meet the Requirements of the 2002 ppt
... 2004 RAND Corporation All rights reserved No part of this book may be reproduced in any form by any electronic or mechanical means (including photocopying, recording, or information storage and ... task, and is made even more complicated by the need to project estimates into the future to meet the reporting requirements In Table 1.1 we break down the process of estimating the savings into ... to determine the level of savings and thus whether the cost reduction goal is met The purpose of this report is to support the Air Force’s efforts to meet the cost reduction goals and reporting...
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the impact of changes in bank ownership structure around the world
... Once these hard information customers are separated from the pool of other borrowers, the remaining soft information clients are left in a worse pool of borrowers, which causes them to either ... hand, the poor protection of minority shareholders in some countries may be forcing minority shareholders to either increase their stakes (thereby becoming large shareholders themselves), or to ... state-controlled banks They also find support for the importance of privatizing banks by selling them to strategic foreign investors Banks privatized in such manner are more cost and profit efficient...
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Effect of changes in dissolved oxygen concentrations on the spatial dynamics of the gulf menhaden fishery in the northern gulf of mexico
... both inshore and offshore of the hypoxic zone, as has been shown for other species (Craig 2012; Craig and Bosman 2013) The depths of the two modes corresponded to the approximate inshore and offshore ... the beginning of the season to a first peak between week and week 14 (early June to mid-July) After the initial peak, the response variables declined for a period of time before increasing to a ... during the beginning of the fishing season (April–May), plateaued or peaked during the middle of the season (June–August), and then declined towards the end of the season (September–November) Catch...
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Báo cáo khoa học: The propagation of hamster-adapted scrapie PrPSc can be enhanced by reduced pyridine nucleotide in vitro pdf
... native PrPC in brain homogenates and recombinant PrP can be converted more efficiently into PK-resistant isoforms by PrPSc with the help of NADPH, enhancing the conversion from PrPC to PrPSc in PMCA ... leading to the protein being more easily converted to PrPSc The level of extracellular NADPH or NADH has not been determined [35], so it is unclear whether PrPC on the cell surface can be in uenced ... PMCA in the presence of NADPH had further propagation ability To determine whether newly generated PMCA PrPSc by addition of NADPH could further propagate in the PMCA system in the absence of NADPH,...
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Báo cáo khoa học: What’s in a covalent bond? On the role and formation of covalently bound flavin cofactors doc
... Covalent flavoproteins and their modes of covalent FAD or FMN binding The family to which each flavoprotein belongs to is indicated according to the following codes and PFAM ordering: pyridine nucleotide-disulfide ... covalent cofactors, e.g in disulfide reductases [2], and in other proteins, redox cofactors are formed in situ from amino acyl groups [3], e.g topaquinone in serum amine oxidase, tryptophan tryptophylquinone ... flavin cofactors experimental data Covalent flavinylation can increase protein stability, ensure cofactor binding, and ⁄ or induce a relatively high redox potential of the cofactor Although the...
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Interfacial Compatibility in Microelectronics : Moving Away from the Trial and Error Approach ppt
... gradually restored towards their values before deformation The driving force of the restoration processes is the release of internal energy bound in the material during deformation During deformation ... transmitted, in any form or by any means, with the prior permission in writing of the publishers, or in the case of reprographic reproduction in accordance with the terms of licenses issued by the Copyright ... part of the work consumed is stored in the material in the form of lattice defects, primarily in dislocations The increased internal energy of deformed material acts as the driving force for the...
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báo cáo hóa học: " Changes in spatiotemporal gait variables over time during a test of functional capacity after stroke" pot
... second important finding related to the quantification of resting behavior links to the potential for the observation of resting to be used as a clinical prognostic indicator Page of (page number not ... future studies, to both confirm these findings in individuals with stroke and examine this effect in other populations to examine whether other factors such as aging may contribute to this observation ... determine if sensorimotor control worsened over time and contributed to the decreased performance Sensorimotor control of gait may be examined through the assessment of both spatial and temporal...
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Báo cáo y học: "Assessing post-traumatic stress disorder in South African adolescents: using the child and adolescent trauma survey (CATS) as a screening tool" docx
... Badly beaten Shot or stabbed Terrible fire or explosion Chemical or other deadly poisoning Bad storm, flood, tornado, hurricane or earthquake Bad car, boat, bike, train, or plane accident Other ... other self-rating scales, the CATS includes both a trauma exposure list and a PTSD inventory Most self-rating scales focus on one or the other The trauma list includes both direct (happened to ... event In the PTSD section, participants are asked to rate how often in the past month they have had experiences that inventory the major symptom domains of PTSD – reexperiencing, avoidance and...
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Báo cáo y học: "Gene expression profiling in murine autoimmune arthritis during the initiation and progression of joint inflammation" pps
... We thereR199 Being aware of the importance of data reproducibility, we determined the optimal number of arrays to be included in experimental design by monitoring the convergence of variance for ... detected even before the migration of inflammatory leukocytes into the joints To characterize major biological functions in context with the initiation phase of the disease, we assigned the 37 early ... 4) These genes were mostly related to cytoskeleton remodeling, the formation of cell junctions, and the production of structural molecules such as desmin, β-3 laminin, envoplakin, and dystonin...
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Báo cáo y học: "Morphological changes in diabetic kidney are associated with increased O-GlcNAcylation of cytoskeletal proteins including a-actinin " docx
... complications and in the up-regulated gene expression of transforming growth factor-beta1, plasminogen activator inhibitor 1, and upstream stimulatory factor proteins in mesangial cells, leading to mesangial ... O-GlcNAcylation of a-actinin and actin may affect the crosslinking to actin and cause the morphological changes seen in the podocyte foot processes in the glomeruli and in the microvilli of tubules a-Actinin ... immunoreactivity of a-tubulin did not change, that of immunoreactivity of actin, aactinin and myosin was increased in the diabetic glomerulus 2) Whereas the intensity of immunoreactivity of actin and myosin...
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several epidemiological characteristics of acute encephalitis syndrome suspected to be caused by banna virus in some provinces of vietnam
... Moreover, Banna virus exist in some migratory birds and the migration of these birds enables the virus to spread to other areas Mosquito has been confirmed as Banna virus transmission vector in ... medical record Study Culex mosquito vector: Collect mosquito samples in provinces with high number of patients with AES suspected to be caused by viruses in Northern, Central, Southern and Tay Nguyen ... from 18h00 to 22h00 in the winter and 19h00 to 23h00 in the summer Laboratory material and testing techniques Samples including patients' ceresbrospinal fluid samples and mosquito samples collected...
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Báo cáo khoa học: "Fertility of frozen-thawed stallion semen cannot be predicted by the currently used laboratory methods" ppt
... equal volume of this mixture and diluted sperm were combined and shaken for min, then incubated for 30 at 34°C and measured with the fluorometer, using the same fluorometer settings as in the plasma ... Motility has been claimed by other investigators to be a poor predictor of pregnancy rates [6,31] However, Voss and his coworkers [6] suggested that although the relationship between motility and fertility ... status, insemination volume, timing of insemination, and number of sperm per dose Standardizing all these variables is clearly not possible Sperm numbers and concentration The total number of sperm/AI...
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Báo cáo y học: "A Comparative Effectiveness Study of Bone Density Changes in Women Over 40 Following Three Bone Health Plans Containing Variations of the Same Novel Plant-sourced Calcium"
... study per-protocol (PP) For Plan 2, a total of 274 S‟s were invited to complete a bone density test and to have the study components explained to them prior to enrolling for the study Of these, 158 ... Therefore, instead of using changes from baseline in all 37 chemistries, we compared the number of changes in scores that were in the normal or acceptable ranges at baseline with those that became ... challenges to America‟s bone health that could benefit from supplementation The increasing number of the elderly is extending the progressive age-related decline in BMD, thereby increasing the need for...
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Characteristics of Leachate from Citrus Groves and their Changes in the Collecting Reservoirs in Matsuyama, Japan
... the middle parts of the grove from points Sampling points St.1 and St.2 are in the same stream, and sampling point St.3 is in the other stream The two streams flow together to be one stream and ... streams flow together from 47 m above sea level The water in the stream is the leachate from the grove and it flows into a collecting reservoir at the foot of the hill The surface area of the reservoir ... In this study, runoff characteristics of the materials from citrus grove were investigated and their behaviors in the collecting reservoirs were discussed The main results obtained from the investigation...
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Tài liệu Báo cáo khoa học: Reversible tetramerization of human TK1 to the high catalytic efficient form is induced by pyrophosphate, in addition to tripolyphosphates, or high enzyme concentration ppt
... 29] In the light of these effects, the complex regulatory and structural properties of hTK1 may be important for maintaining a balanced supply of the DNA precursor This underlines the importance ... tetrameric and dimeric forms in Figs and exhibited low or high catalytic efficiency Therefore, the various incubated hTK1 forms from Figs and were analyzed for their kinetic behavior with dThd, and the ... that of non-incubated hTK1 The two TK1 forms can therefore be referred to as the high- and lowefficiency forms To explain the apparent negative co-operativity, a model has been proposed whereby the...
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Tài liệu Báo cáo khoa học: Changes in rat liver mitochondria with aging Lon protease-like activity and N e-carboxymethyllysine accumulation in the matrix doc
... for 10 and then at 100 000 g for 45 The supernatant (containing matrix protein) was stored at )80 °C for further determinations of protease activity and the level of carboxymethylated protein ... may be the result of either a loss of efficiency in relation to damaged protein and /or a decrease in the amount of this protein in the matrix We have not detected any significant modification in the ... matrix We identified the major proteins in the mitochondrial matrix by performing SDS/PAGE separation and staining the gel with Coomassie blue or Western blotting Analysis of the SDS/PAGE revealed...
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Tài liệu Báo cáo khoa học: Adaptive changes in the expression of nuclear and mitochondrial encoded subunits of cytochrome c oxidase and the catalytic activity during hypoxia pptx
... to proceed for 45 at 33 °C Aliquots were used to determine the level of 32P incorporation in to RNA as described before [19] At the end of incubation, the mitochondria were pelleted by centrifugation ... dithiothreitol, 0.1% Chaps and 150 mM NaCl and protease inhibitors [5 lgÆmL)1 pepstatin A, lgÆmL)1 aprotinin, and mM phenylmethanesulfonyl fluoride]) and lysed by three cycles of freezing and thawing in ... tension is maintained at less than Torr [13] We have used modular incubator chambers (BillupsRothernberg, CA, USA) for creation of a nonfluctuating hypoxic environment The chambers were maintained at...
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Tài liệu Báo cáo khoa học: Moult cycle-related changes in biological activity of moult-inhibiting hormone (MIH) and crustacean hyperglycaemic hormone (CHH) in the crab, Carcinus maenas From target to transcript ppt
... is a minor secretory product of Carcinus YO [11] Loss of sensitivity of YO to the inhibitory in uence of crude SG extracts during premoult has been noted for the shrimp P vannamei [9] but in this ... cycle dependent Rather surprisingly, there were no changes in receptor affinity or number during the moult cycle (excepting the possible recruitment of MIH receptors to the organ during postmoult); ... at the receptor level In view of these observations, we also investigated levels of MIH and CHH peptides in the sinus gland and levels of transcripts in XO neurones during the moult cycle, to...
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Accounting for Changes in Social Support Among Married Older Adults: Insights From the MacArthur Studies of Successful Aging pptx
... imposed by the wording of the support items, for example, “loved and cared for” and “listens to worries.” Although the specific items used are similar to those of other support inventories, the specific ... and in their likelihood of being pruned from or added to others’ networks Referred to in the support literature as evocative qualities, personal characteristics may be critical determinants of ... patterns of support (or lack of it) by source and type We focus on three types of behaviors: emotional support, instrumental support, and negative behaviors Drawing on the taskspecific and functional-specificity...
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International Accounting Standard 21 The Effects of Changes in Foreign Exchange Rates potx
... that the foreign operation can be included in the financial statements of the reporting entity by consolidation, proportionate consolidation or the equity method 45 The incorporation of the results ... changes in exchange rates up to the end of the reporting period of the reporting entity in accordance with IAS 27 The same approach is used in applying the equity method to associates and joint ... gives priority to the primary indicators in paragraph before considering the indicators in paragraphs 10 and 11, which are designed to provide additional supporting evidence to determine an entity’s...
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