... shows the contribution of thisstrategy to the development of plants with biofarming potential in the frame of a highdemand of natural and ecologically accepted sources of renewable compounds ... the evolution of vascular plants. The case of Fld and Cyt c6shows that reintroduction of these genes in the proper subcellularcompartment of model and crop plants restored some of the selective ... roots and stolons of Glycyrrhizaplants is glycyrrhizin, which has the sweetness of about 200 times greater thanthat of sucrose. Glycyrrhizin is a conjugate of two molecules of glucuronic acidand...
... malonyl-CoA and CPT1c in the treatment of obesity Michael J. Wolfgang and M. Daniel LaneDepartment of Biological Chemistry, The Johns Hopkins University School of Medicine, Baltimore, MD, USAIntroductionAll ... malonyl-CoA;neurometabolism; nutrient sensing; obesity CorrespondenceM. J. Wolfgang, Department of BiologicalChemistry, Johns Hopkins University School of Medicine, Center for Metabolism and Obesity Research, 475 Rangos ... major user of long-chain fattyacids making a brain-specific isoform intriguing.CPT1c was identified and cloned from in silicosequences as a highly homologous member of theCPT1 class of enzymes...
... emerging targets for treatment of obesity and related metabolic diseasesTsuyoshi Kadomatsu, Mitsuhisa Tabata and Yuichi OikeDepartment of Molecular Genetics, Graduate School of Medical Sciences, Kumamoto ... metabolism;insulin resistance; metabolic syndrome; obesity; obesity- related metabolic diseaseCorrespondenceY. Oike, Department of Molecular Genetics,Graduate School of Medical Sciences,Kumamoto University, ... roles of ANGPTL2 and ANGPTL6 ⁄ AGF in obesity andrelated metabolic diseases, and discuss the possibility that both could func-tion as molecular targets for the prevention and treatment of obesity...
... most prevalent form of MetS isassociated with abdominal (visceral) obesity and thatthis type ofobesity contributes to insulin resistance(IR) and the increased release of cytokines, as well ... risk of T2DM, hypertension and CVD;however, the exact underlying pathophysiologicalmechanisms by which obesity increases the risk of VD remains the subject of intensive investigation [20]. Obesity ... deficiencyand hypogonadism-induced obesity remain the subject of intense investigation.Several hypotheses have discussed the relationship of androgen deficiency and obesity. That obesity iscommonly associated...
... aggregation in the presence of amixture of annexins of different subtypes. The profile of liposome aggregation was simply the sum of theresults obtained with a single subtype of annexin, sug-gesting ... theinvolvement of the N-terminus of annexin A2 in itsbinding to dicalcin. The binding affinity of the N-termi-nus or the core domain has not yet been determined.The binding of dicalcin–annexins ... above, various pairing of S100 and ann-exins may be an intrinsic and conventional mechanism of the S-100 annexin system to function in a variety of tissues. The participants of these complexes are...
... mode of action of RMI1 in the regulation of energy homeostasis might be based on the regulation of adipocyte hyperplasia. Studies have shown that siRNAknockdown of RMI1 resulted in suppression of ... cause of adult obesity, and hyperplasia of adipocytes in obese adults some-times occurs secondary to adipocyte hypertrophy, pos-sibly due to an increased number of adipocytescapable of secreting ... escalating prevalence ofobesity is one of the most pressing healthconcerns of the modern era, yet existing medicines to combat this globalpandemic are disappointingly limited in terms of safety and...
... use of drugs to counteract obesity risk factors or simply to the latency of the effect. This analysis does not take account of the impact of childhood obesity. The health consequences of overweight ... prevalence of obesity THE DETERMINANTS • 132. The determinants of obesity Main messages• The simultaneous presence of physical inactivity and poor diet to a large extent explains the obesity ... sense of fatalism about their health. Lower socioeconomic status not only increases the risk ofobesity but may result from obesity. Several stud-ies have noted that obesity increases time off...
... Scientific Biologyof Wastewater Treatmen t (New Edition) bwtNature of Wastewater 23population of a city the size of Manchester will produce an organic loadequivalent to the human population of a ... concentration of the wasteTable 1.10. Comparison of the percentage consumption of water for various pur-poses in a home with an office; indicating the source and make-up of wastewaterfrom these types of ... processing.January 19, 2004 14:33 World Scientific Biologyof Wastewater Treatmen t (New Edition) bwtPreface to the Second EditionSince writing the first edition ofBiologyof Wastewater Treatment thewastewater...
... of obesity. The guideline addresses:primary prevention ofobesity in children, young people and adults treatment of overweight /obesity by diet and lifestyle interventions treatment ofobesity ... MANAGEMENT OF OBESITY A Cochrane systematic review examined the effectiveness of interventions to improve health professionals’ management of obesity. Interventions included training and provision of ... slowing the rate of eating reinforcement of changes relapse prevention strategies for dealing with weight regain. 73 OBESITY IN ADULTS3 Obesity in adults3.1 PREVALENCE OFOBESITY IN ADULTSThe...
... over‐handlingStress…noise,vibrations,odors,overhandling– Breedingcessation–Resorption of fetusesResorption of fetuses– Cannibalism of litters•Health status•Healthstatus• SeasonaleffectsJAX®ServicesJAXServices• ... myMaleAnatomyCookMJ.1965.TheAnatomy of theLaboratoryMousehttp://www.informatics.jax.org/cookbook/Estrous Cycle Interruption: PheromonesEstrousCycleInterruption:PheromonesBruceEffect‐ 1959• Exposure of apregnantfemaletoanunknownmaleresultsinpre‐ ... Diploidspermatogonialstemcells– lifetimesupply•12 stages of spermatogenesis in theseminiferoustubules•12stages of spermatogenesisintheseminiferoustubules– 35days•...
... Department of Ichthyology and Aquatic Environment, University of Thessaly, 38446, Nea Ionia, Volos, GreeceReceived 19 February 2007; Accepted 29 May 2009Abstract. The reproductive biologyof the ... basis at the mouth of the river using a bag seine net and overall a total of 4 563 individuals were collected. The total length of males ranged between 2.5 and 6.0 cm and that of females between ... throughout most of the year may be a specific character of the marbled goby (F o u d a et al. 1993), as well as of some other goby species (M i l l e r 1984). The marbled goby, one of the few species...
... passage of a wide variety of anticancer agents. The high incidence of recur‐rence and poor prognosis of malignant gliomas compel the development of more powerfulanti-cancer treatments. Action of ... proliferation, migration, reorganization of ECM and tube formation.The advent of molecular studies allowed a new evaluation of the biologyof gliomas with, alevel of precision that promises interesting ... mention, that genetic instability of high gradegliomas provides the way of angiogenesis independently of hypoxia (such as chronic HIFEvolution of the Molecular Biologyof Brain Tumors and the Therapeutic...
... partitioning of C within the plant and the distribution of root exudates within thesoil after net fixation of 1000 units of C. (Redrawn with permission from the EcologicalSociety of America; ... the coast of southeast Alaska, is one of the best known places for research on primary succession because of the continuous retreat of the glaciers since 1794. Furthermore, records of the retreat, ... If the humpbacked model does not apply for soil46 THE BIOLOGYOF SOILTable 2.3 Effects of cultivation of native bush plots on populations of microarthropods in a tropical Alfisol (0–10 cm). (Adapted...