basic mechanisms mediating cardiomyopathy and heart failure in aging
báo cáo hóa học: " Differential aspects of stroke and congestive heart failure in quality of life reduction: a case series with three comparison groups" pot
... was applied to quantify impairment in activities of daily living such as grooming, walking, transferring, hygiene and voiding (50 points meaning completely independent for all activities) [9] ... evaluates five QOL domains (mobility, pain, self-care, anxiety/depression and usual activities), each with one normal (no complaint) level and two increasingly abnormal levels [11,12] In order to derive ... activities and self-care [17,18] Most (> 50%) stroke patients in our study showed complaints in these same domains Conversely, the CHF group demonstrated significant complaints in mobility and usual...
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báo cáo khoa học: "Patient Care Teams in treatment of diabetes and chronic heart failure in primary care: an observational networks study" pptx
... this in both diabetes patients and CHF patients In diabetes, testing for creatinine is important in identifying affected kidney functioning due to damaged blood vessels and nerves, resulting in ... is worth mentioning that the variation in our outcome ‘disease monitoring’ was mainly related to varying levels of creatinine testing, i.e., monitoring of kidney functioning Clinical research ... knowledge on latest guidelines, and convincement of its benefits Despite recommendations in prevailing practice guidelines, these benefits remain a topic for continuing debate [23] Therefore,...
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Báo cáo y học: "Effect of Acute Administration of an Herbal Preparation on Blood Pressure and Heart Rate in Humans"
... treatment ingestion After eating, an increase in heart rate occurred in all three treatment groups The increase in heart rate does not coincide with the pharmacokinetics including blood levels and ... due, at least in part, to a lack of understanding of the differences in the pharmacokinetic and pharmacological properties between p-synephrine and m-synephrine (phenylephrine) Failure to differentiate ... GJ Coronary spasm and thrombosis in a bodybuilder using a nutritional supplement containing synephrine, octopamine, tyramine and caffeine So African Med J 2008; 98: 372-373 Sander LC, Putzbach...
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Deposit interest rates, asset risk and bank failure in Croatia ppt
... rates, thus squeezing the margins and causing failures of the internally most inefficient banks The remaining two variables, OHER and CM, are both insignificant at lag t-3, and for the other ... program implemented in October 1993 succeeded in bringing inflation under control, and real GDP growth began in 1994 Decisive military actions in May and August 1995, and the signing of the Dayton ... GDP and inflation to pick up changes in income and activity 8 Finally, we use dummy variables for the period before, during and after the banking crisis These dummies are interacted with the interest...
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Báo cáo y học: "Tight perioperative glucose control is associated with a reduction in renal impairment and renal failure in non-diabetic cardiac surgical patients" ppsx
... output (as defined by the definition of RIFLE), and in (1.2%) solely to an increase in serum creatinine Between groups, there were significantly more patients in the Insulin group scoring R, I or ... serum creatinine In the Insulin group there were 342 patients who developed renal injury /failure (scoring R, I or F) In 87 (25.4%) of them, renal injury was solely attributed to low urinary output ... preoperative creatinine 1.2 to < 2.1 mg/ dL, preoperative use of intra-aortic balloon pump (IABP); scoring points: preoperative creatinine ≥ 2.1 mg/dL Patients scoring to points have a predicted incidence...
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Báo cáo y học: "Effects of Astragaloside IV on heart failure in rats" doc
... hypoxia, oxidation, and mechanical load), cytokines (e.g TNF-α, IL-6 and ITF) and neuroendocrine factors (e.g angiotensin II and NO) [15] Gene families Bcl-2 and P53 also take part in the regulation ... outcome of MI in rats where LVIDd is the LV internal diameter in diastole, and LVIDs is the LV internal diameter in systole [20] LV internal diameters were measured according to the guidelines of the ... normal and depressant cardiac function in rats Zhongcaoyao 2001, 32(4):332-334 Liu YY, Shen XT: The comparison of cardiac effects of ASI, milrinone, and ouabain on heart failure in guinea pigs...
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Báo cáo y học: "Clinical review: Post-extubation laryngeal edema and extubation failure in critically ill adult patients" pps
... requiring medical intervention Miller and Cole [27] 1996 100 6 High-pitched inspiratory wheeze requiring medical intervention Kriner and colleagues [8] 2005 462 20 4.3 Inspiratory grunting, whistling ... PES and reintubation rates [4,7,41] In contrast, a single dose of 40 mg methylprednisolone 24 hours before extubation was effective in lowering the incidence of PES and the reintubation rate in ... ventilation and an increased length of both intensive care unit stay and hospital stay increasing the risk for infections and other complications [10,12,31] This unfavorable outcome is reflected in the...
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Báo cáo y học: "Clinical review: Practical recommendations on the management of perioperative heart failure in cardiac surgery" pdf
... intravenous inotropes and/ or IABP are necessary to maintain SBP >80 mmHg and/ or CI >1.8 L/minute/m2 without clinical improvement Failure to wean from inotropes (decreasing inotropes results in ... three clinical heart failure scenarios and the clinical profiles in each scenario Clinical scenarios Clinical profiles in each scenario Precardiotomy heart failure Precardiotomy crash and burn ... Precardiotomy deteriorating fast Deteriorating haemodynamic instability: increasing doses of intravenous inotropes and/ or IABP necessary to maintain SBP > 80mmHg and/ or CI >1.8 L/minute/m2 Progressive...
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Heart failure in congenital heart disease from fetus to adult springer 2010tuyenlab net
... stimulating the renin–angiotensin–aldosterone system, causing peripheral vasoconstriction and increased heart rate Plasma norepinephrine levels are elevated in infants and children with heart failure ... performance index (Tei Index) and Doppler tissue imaging have been reported These tools have provided insight into the mechanisms of disease and may have clinical value in specific disorders when used in ... Aspects of Heart Failure in the Neonate 21 Jack F Price 3 Chronic Heart Failure in Children with Congenital Heart Disease 43 Kimberly Y Lin and Robert E Shaddy 4 Heart Failure in Adults...
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Báo cáo y học: "Different effect of exercise on left ventricular diastolic time and interventricular dyssynchrony in heart failure patients with and without left bundle branch block"
... heterogeneous termination LV isovolumic 338 time intervals were found to be increased at the expense of LV diastolic time in heart failure patients (17,18) Since our findings and other previous ... lack of increase in LV dyssynchrony during dobutamine stress in patients with wide QRS duration (20) In contrast, Kurita et al reported on an increased mechanical dyssynchrony during pacing–induced ... plotted against the corresponding heart rate of each exercise stage and regression analysis was performed An inverse, nonlinear relation between heart rate and LV diastolic time was found in either...
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báo cáo hóa học:" Short term effects of milrinone on biomarkers of necrosis, apoptosis, and inflammation in patients with severe heart failure" pot
... continued to be at the discretion of the attending physician, including inotrope administration and dosing It is well recognized that heart failure leads to increased circulating levels of pro-inflammatory ... for ligand binding, therefore reducing apoptotic signaling Procedures All treatments including milrinone dosing was at the discretion of the patient's attending physician, with initial dosing between ... studies examining natriuretic peptide levels and/ or inflammatory markers during inotrope administration with inconsistent results [8-11] Adding complexity to this picture is data indicating that...
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Báo cáo hóa học: "Early combined treatment with sildenafil and adipose-derived mesenchymal stem cells preserves heart function in rat dilated cardiomyopathy" doc
... lower in group than in groups 3, 4, and 5, significantly lower in group than in groups and 5, and also notably lower in group than in Page 10 of 16 group This finding indicates that early combined ... groups and These findings indicate that the expression of cytochrome C, an index of energy supply and storage in mitochondria, was notably lower in group than in groups and The increase in cytosolic ... laboratory assay and troubleshooting FYL and HKY participated in refinement of experiment protocol and coordination and helped in drafting the manuscript 15 16 17 Competing interests The authors...
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Báo cáo hóa học: "Hybrid approach of ventricular assist device and autologous bone marrow stem cells implantation in end-stage ischemic heart failure enhances myocardial reperfusion" doc
... Conception and design, provision of patients, data analysis and interpretation, manuscript writing PA Conception and design, data analysis and interpretation, manuscript writing HA Data analysis and interpretation ... Conception and design, data analysis and interpretation, manuscript writing All authors read and approved the final manuscript Competing interests The authors declare that they have no competing interests ... cells in ischemic heart failure Proc Natl Acad Sci USA 2005, 102:8692-8697 Fedak PW: Paracrine effects of cell transplantation: Modifying ventricular remodeling in the failing heart Semin Thorac...
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Báo cáo sinh học: "Increase of plasma IL-9 and decrease of plasma IL-5, IL-7, and IFN-g in patients with chronic heart failure" potx
... interleukins and 6, TNF-a, matrix metalloproteinases, neuroepinephrine, renin, galectin-3 [16-18], some of which are also important tools in the diagnosis and pathogenesis of heart failure, in the ... circulating levels of tumor necrosis factor in severe chronic heart failure N Engl J Med 1990, 323:236-236 Mann DL, Young JB: Basic mechanisms in congestive heart failure Recognizing the role of proinflammatory ... ovals), are linked to each other in terms of expression and/ or function (black thick lines), and to a number of molecules, namely Norepinephrine, Endothelin-1, IL-1A, Galectin-3, TNFa, IL-6 and IL-18...
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báo cáo hóa học:" Increase of plasma IL-9 and decrease of plasma IL-5, IL-7, and IFN-g in patients with chronic heart failure" pptx
... interleukins and 6, TNF-a, matrix metalloproteinases, neuroepinephrine, renin, galectin-3 [16-18], some of which are also important tools in the diagnosis and pathogenesis of heart failure, in the ... circulating levels of tumor necrosis factor in severe chronic heart failure N Engl J Med 1990, 323:236-236 Mann DL, Young JB: Basic mechanisms in congestive heart failure Recognizing the role of proinflammatory ... ovals), are linked to each other in terms of expression and/ or function (black thick lines), and to a number of molecules, namely Norepinephrine, Endothelin-1, IL-1A, Galectin-3, TNFa, IL-6 and IL-18...
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Sudden Death in Patients with Myocardial Infarction and Left Ventricular Dysfunction, Heart Failure, or Both pdf
... LXRα is expressed predominantly in tissues involved in lipid homeostasis in the liver, intestine, adipose tissue, and macrophages LXRα and LXRβ are equally effective in promoting reverse cholesterol ... increased despite the fact that all patients, according to the study design, were receiving inhibitors of the renin–angiotensin system and the majority were receiving beta-blockers and aspirin ... myocardial infarction Table Event Rate and Cumulative Incidence of Events during Follow-up.* Time after Myocardial Infarction No at Risk at Beginning of Interval No Who Died of Any Cause during Interval...
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Báo cáo khoa học: "Skeletal muscle oxygen saturation does not estimate mixed venous oxygen saturation in patients with severe left heart failure and additional severe sepsis or septic shock" docx
... splanchnic and renal circulations falls, whereas flow to the heart and brain is maintained [28] This results in a fall in the oxygen content of blood in the inferior vena cava As a consequence, in shock ... norepinephrine and increases during nitroprusside infusion severe sepsis/septic shock Agreement between SvO2 and thenar muscle StO2 in the absence of severe sepsis/septic shock Shown are Bland and ... and its analysis and interpretation; and for drafting the manuscript HM was responsible for conception and design of the study; for acquisition of data, and its analysis and interpretation; and...
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Báo cáo y học: "Transpulmonary thermodilution-derived cardiac function index identifies cardiac dysfunction in acute heart failure and septic patients: an observational study" pptx
... medians (interquartile ranges) Creatinine, norm 70 to 105 μmol/L Troponin T, norm
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Báo cáo y học: " Near-infrared spectroscopy during stagnant ischemia estimates central venous oxygen saturation and mixed venous oxygen saturation discrepancy in patients with severe left heart failure and additional sepsis/septic shock" potx
... drain into the inferior vena cava or coronary sinus will not be involved in this measurement Healthy resting individuals have a ScvO that is slightly lower than the SvO2 [3] In heart failure and ... in periods of hemodynamic instability In shock states, blood flow to the splanchnic and renal circulations falls, while flow to the heart and brain is maintained [21] This results in a fall in ... measurement to determine ScvO (%) and SvO (%), respectively In view of known problems arising during sampling from the pulmonary artery, including the possibility of contaminating arterial blood...
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Báo cáo y học: "Direct comparison of serial B-type natriuretic peptide and NT-proBNP levels for prediction of short- and long-term outcome in acute decompensated heart failure" ppt
... finding may include an increased neurohumoral and cytokine activation found in patients with advanced HF, leading to higher levels of tumor necrosis factor (TNF) and other inflammatory cytokines ... abnormalities and outcome in patients with chronic heart failure: data from the Candesartan in Heart Failure: Assessment of Reduction in Mortality and Morbidity (CHARM) program Eur J Heart Fail ... common in patients with HF and independently predict adverse outcome [52-54] In a post hoc analysis of the CHARM (Candesartan in Heart Failure: Assessment of Reduction in Mortality) study, Allen and...
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