b the answer is in paragraph 3 after scannning for the name the important word is distinction which means different in this case
Tài liệu Báo cáo khoa học: The crystal structure of human a-amino-b-carboxymuconatee-semialdehyde decarboxylase in complex with 1,3-dihydroxyacetonephosphate suggests a regulatory link between NAD synthesis and glycolysis ppt
... also because of its direct involvement in substrate binding (Fig 3A ,B) Indeed, as detailed above, Asp291 stabilizes DHAP through interaction with the inhibitor carbonyl group, and is therefore ... ligand-bound form and can be used to provide insights into catalysis In particular, the residues involved in inhibitor binding can be suggested to be important players for recognition of the physiological ... centre and the ligand binding site The hACMSD active site is located in a crevice on the protein surface at the C-terminal opening of the b- barrel (Fig 2), with a Zn2+ ion occupying the metal...
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Tài liệu In this lab, 2 ISDN routers are required. If ISDN routers are not available, review the lab to become familiar with the process. An Adtran Atlas550 ISDN emulator is used to simulate the switch/ISDN cloud. pdf
... reload instructions at the end of this lab Perform those steps on all routers in this lab assignment before continuing Step Configure the router Configure the following according to the chart: • The ... Please refer to the chart at the end of the lab to correctly identify the interface identifiers to be used based on the equipment in the lab The configuration output used in this lab is produced ... interfaces in the device This interface chart does not include any other type of interface even though a specific router may contain one An example of this might be an ISDN BRI interface The string in...
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Tài liệu Báo cáo khoa học: High affinity copper binding by stefin B (cystatin B) and its role in the inhibition of amyloid fibrillation docx
... probably form part of the copper binding sites in this protein Although there are four histidines in the C-terminal, another histidine is present at position 18, and given the folded state of the ... genes which code for increased proteolysis, apoptosis and glial cell activation Copper homeostasis is important in the brain, therefore the role of copper binding or loss of its binding could be ... Copper binds to cystatin B change but lacks any copper binding capacity This point mutation lies within the C-terminal region and therefore could affect the structure of this part of the protein...
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Báo cáo Y học: Solution structure of the Alzheimer amyloid b-peptide (1–42) in an apolar microenvironment Similarity with a virus fusion domain potx
... been proposed that HA_fd inserts both helical stretches into the membrane [38 ] Accordingly, it is possible that the mechanism of membrane interaction and destabilization is different in the case ... soluble form of Ab-(1–42) in isotropic media is necessary not only to shed some light on the steps involved in the fibrillogenesis, but, most of all, to evaluate the role of Ab-(1–42) in the interaction ... converted into upper distance bounds with the routine CALIBA of the program package DYANA [29] After discarding redundant and duplicated constraints, the final list included 130 intraresidue and 2 83 interresidue...
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Báo cáo khoa học: b-Secretase cleavage is not required for generation of the intracellular C-terminal domain of the amyloid precursor family of proteins pot
... As the band migrating at 94 kDa was recognized by antibodies directed to both the ectodomain and the C-terminus, this band appears to be FLAPLP1 In contrast, the band migrating at 83 kDa, which ... (Fig 3B) , whereas this is not the case for BACE1 KO, where we observed a substantial decrease in APLP2s level (Fig 3A ,B) and a minor increase in total APLP2 CTF level (Fig 6D) However, there is ... 1E) The fact that the 100 kDa band detected in the NaCl ⁄ Tris mouse brain extracts was revealed by the ectodomain-directed antibody 22C11 but not by the C-terminal specific antibody C8 indicates...
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Báo cáo khoa học: Glycogen synthase kinase 3b and b-catenin pathway is involved in toll-like receptor 4-mediated NADPH oxidase 1 expression in macrophages ppt
... GSK 3b through phosphorylation, and the inactivated GSK 3b inhibits the degradation of b- catenin, promoting translocation into the nucleus It is hypothesized that the translocated b- catenin forms ... that GSK 3b- b-catenin is involved in Nox1 expression GSK 3b, through TLR signaling, is necessary in inflammation For example, it has been reported that GSK 3b regulates TLR-mediated cytokine production ... 2010 FEBS J.-S Kim et al GSK 3b- b-catenin is involved in Nox1 expression A β-catenin β-actin 15 30 45 60 LPS (min) B β-catenin β-actin 10 50 100 500 LPS (ng·mL–1) C β-catenin (short) β-catenin (long)...
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The History of Banks: To Which Is Added, a Demonstration of the Advantages and Necessity of Free Competi- tion In the Business of Banking. Richard Hildreth doc
... something like a move backwards during the close of 1 833 and the beginning of 1 834 This event is commonly known as the Panic of 1 833 34 The history of this panic which is at once curious, instructive ... established at Paris, which issued bank-notes, in imitation of the private banks in Great Britain The three principal institutions of this kind were the Caisse d Escompte, the Comptoir, and the ... of bank payments, which had so long been in use at Venice This was the origin of the BANK OF AMSTERDAM The original subscribers to the bank paid into its vaults certain sums in the current coin,...
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Báo cáo khoa học: Quenched hydrogen ⁄deuterium exchange NMR characterization of amyloid-b peptide aggregates formed in the presence of Cu2+ or Zn2+ ppt
... suggested to be either Tyr10 [30 32 ], Glu11 [33 ], or the N-terminus [34 ,35 ] A weaker binding site for zinc, involving Asp 23 Lys28, has also been identified [35 ] Ab assemblies formed in the presence ... laterally assembled, the N-terminal metalbinding region of the peptide will be in close proximity to both the C-terminal and turn residues, possibly interfering with these regions This explains how ... residues in the aggregate core This is similar to the arrangement found in Ab(1–42) fibrils, where the C-terminal residues strengthen the hydrophobic interactions within the core of the fibrillar...
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Báo cáo Y học: The DNA-polymerase inhibiting activity of poly(b-L-malic acid) in nuclear extract during the cell cycle of Physarum polycephalum pot
... were histones, and probably other DNAbinding proteins [2] To obtain an optimal response by the reporter polymerase to a varying inhibitory activity in the nuclear extract, the amounts of the added ... similar for the unresolved DNA polymerases The high basal level was explained by the contribution of DNA polymerase b- like, which was not inhibited by PMLA The results show that the minimum in the inhibitory ... polymerase b- like (which was not inhibited by PMLA) was measured in parallel and subtracted from the crude value for vi The inhibitory activity is defined in terms of the reciprocal value of the inhibition...
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– THE GRE VERBAL SECTION – 4. Once you understand a question, try to answer it in your own potx
... a a a a a b b b b b b b c c c c c c c d d d d d d d e e e e e e e 10 11 12 13 14 a a a a a a a b b b b b b b c c c c c c c d d d d d d d SENTENCE COMPLETION a a a a a a a b b b b b b b c c c c ... of giving birth in Brabant e the evolution of legal systems within the provinces 14 In this passage, the author maintains that which of the following continued after unification of the provinces? ... To be audacious is to be recklessly bold or daring To be timid is to lack the capacity to be bold or daring 13 a To be palpable is to be capable of being touched or felt, to be tangible To be...
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information in this document is subject to change without notice. the names of companies, products, people, characters,
... Determining the naming structure for the proposed metadirectory includes defining the naming context, which is the top level name for the metadirectory namespace, and defining the organizing structure ... requirements This information enables you to determine who will be able to log on to the metadirectory, what information they will be able to access, and what information is accessible by other users BETA ... information between the metadirectory and the connected directories During the planning phase, you established the design of the attribute flow by: ! Determining which attributes will be stored in each...
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Failure is the mother of successComment in this saying doc
... strategies and finally we will succeed Our success is due to our unflinching determination after bitter failures Demosthenes, the greatest Athenian orator, before reaching the acme of his glory, had ... shouting and roaring with deafening sounds of waves and in the end he acquired a convincing and sonorous voice as he had wished The above saying is quite right if it is applied to the pupils’ lives ... are weak at certain subjects, not be disappointed Be consistent in our study We should learn more from our friends, our teachers and others and listen to their advice Thus, in the long run, we...
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Báo cáo khoa học: "Upper abdominal body shape is the risk factor for postoperative pancreatic fistula after splenectomy for advanced gastric cancer: A retrospective study" ppsx
... surrounding tissue Therefore, there might be the risk for damaging the pancreatic substance without noticing In our present study, no prospective data are available to correlate the texture of the ... pancreas Therefore, future studies should be designed to capture this information and investigate the risk of POPF by analyzing the correlation between body shape, visceral fat around pancreas, and the ... analysis were included in the logistic regression analysis All analyses were performed using the SPSS program version 11.0.1J for Windows (SPSS Inc., Chicago, IL) This study was approved by our institutional...
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Báo cáo y học: "Midregional pro-Adrenomedullin in addition to b-type natriuretic peptides in the risk stratification of patients with acute dyspnea: an observational study" ppt
... honoraria from Abbott, Bayer, Biosite, Brahms, Roche, and Dade Behring AB is an employee of BRAHMS AG, which is a company developing and marketing in vitro diagnostic products, including the MR-proADM ... Antman EM, Cannon CP, Braunwald E: Multi- Available online http://ccforum.com/content/ 13/ 4/R122 32 33 34 35 36 37 38 39 40 41 42 43 marker approach to risk stratification in non-ST elevation acute ... superior to BNP in predicting short-term mortality after 30 days This is in line with studies showing that ADM and the more stable MR-proADM are independent predictors of prognosis in patients...
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The politics of land use conversion in china case study of a guangdong county 3
... 277 73 27 834 8 833 1 4245 Services (76.8%) (0.07%) ( 23% ) (66%) (33 .8%) Industrial, Mining 21 93 1956 14 733 9121 and Warehouses (52.8%) (0.07%) (47.1%) (61.8%) (38 .2%) Housing 41570 11879 533 01 31 907 ... 44 Chan Kam Wing, “Urbanization and Urban Infrastructure Services in the PRC” in Christine P W Wong (ed.), Financing Local Government in the People’s Republic of China (Hong Kong: Oxford University ... 108, No 3, pp 599 70 Incidentally, it is an open secret that the price of rent is incorporated into property prices in China This is to say that consumers bear the cost of rent-seeking while the...
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Comparing the cultural and linguistic analysis of the English word “meal” and words relating to it in contrast with Vietnamese equivalents.
... catching Putting tray in flowered mat, on platform, bamboo tray even on bed is Vietnamese habit and this dies hard In fact, serving tray on the table is amended into the Vietnamese habit But using ... characteristics, meaning is certainly the most important In English, the philosopher Wittgenstein said in Words and their meaning that the meaning of the word is its use in the language Also according ... sángor b a điểm tâm, but today this word is used to call name of a meal in the morning To the English, breakfast is the most important meal in a day because it provides energy for the body to...
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Tài liệu Đề Thi Thử Đại Học Khối A, B Hóa 2013 - Phần 16 - Đề 3 pptx
... Fe2O3 ; 19 ,32 B Fe3O ; 28,98 C Fe2O3 ; 28,98 D Fe3O4 ; 19 ,32 Câu 15: Nếu vật làm hợp kim Fe-Zn b ăn mòn điện hoá trình ăn mòn A Kẽm đóng vai trò catot b oxi hoá B Sắt đóng vai trò catot b oxi ... tích khí đo điều kiện) Mối quan hệ a b là: A a = 0,7 5b B a = 0 ,3 5b C a = 0, 8b D a = 0, 5b Câu 35 : Cho 15,84 gam este no, đơn chức, mạch hở tác dụng vừa đủ với 30 ml dung dịch MOH 20% (d=1,2g/ml) ... 0,1 mol X phản ứng vừa đủ với V lít dung dịch Br2 1M Giá trị V là: A 0,4 B 0,5 C 0,7 D 0 ,3 Câu 37 : Hỗn hợp b t X gồm BaCO3, Fe(OH)2, Al(OH )3, CuO, MgCO3 Nung X không khí đến khối lượng không đổi...
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Tìm thêm: xác định các mục tiêu của chương trình xác định các nguyên tắc biên soạn khảo sát các chuẩn giảng dạy tiếng nhật từ góc độ lí thuyết và thực tiễn khảo sát chương trình đào tạo của các đơn vị đào tạo tại nhật bản khảo sát chương trình đào tạo gắn với các giáo trình cụ thể tiến hành xây dựng chương trình đào tạo dành cho đối tượng không chuyên ngữ tại việt nam điều tra đối với đối tượng giảng viên và đối tượng quản lí điều tra với đối tượng sinh viên học tiếng nhật không chuyên ngữ1 khảo sát thực tế giảng dạy tiếng nhật không chuyên ngữ tại việt nam khảo sát các chương trình đào tạo theo những bộ giáo trình tiêu biểu nội dung cụ thể cho từng kĩ năng ở từng cấp độ xác định mức độ đáp ứng về văn hoá và chuyên môn trong ct phát huy những thành tựu công nghệ mới nhất được áp dụng vào công tác dạy và học ngoại ngữ đặc tuyến mômen quay m fi p2 đặc tuyến tốc độ rôto n fi p2 động cơ điện không đồng bộ một pha sự cần thiết phải đầu tư xây dựng nhà máy thông tin liên lạc và các dịch vụ từ bảng 3 1 ta thấy ngoài hai thành phần chủ yếu và chiếm tỷ lệ cao nhất là tinh bột và cacbonhydrat trong hạt gạo tẻ còn chứa đường cellulose hemicellulose chỉ tiêu chất lượng 9 tr 25