... FEBS J Borloo etal A B C D other Statistical analysis (Student s t-test) between the MR-1R values andthe sum ofthe values ofthe omcA– andthe omcB– mutants revealed that there is no statistically ... acid reduction reported by Marshall etal [15] thus appears to result not from disturbed catalysis, but rather from hampered substrate binding Ofthe other metals tested in this study [V(V) and ... in vitro Kobs values determined by Marshall etal [15] andthe in vivo kcat values determined in our study also differ, although to a lesser extent (six-fold) This discrepancy can most likely be...
... This experiment was repeated three times Statistical analysis SPSS®15.0J (SPSS Inc, USA) was used to perform the statistical analyses including one-way analysis of variance (ANOVA) followed by Dunnett s ... Mattson MP: The endoplasmic reticulum stressresponsive protein GRP78 protects neurons against excitotoxicity and apoptosis: suppression of oxidative stress and stabilization of calcium homeostasis ... ER stress response andthe downstream consequences of ER stress signalling Recently, it was reported that HCV NS2 protein activated endoplasmic reticulum stress signalling, HCV NS2 expression...
... MRI radiologist or other suitably trained specialist review all the images or just the baseline images in a longitudinal study This will also add tothe cost ofthe research study Despite the increasing ... precise prevalence estimate However, this is the first study in this area Our findings raise issues for the planning of studies and ethical issues related tothe obligation ofthe physician-researcher ... importanceof ensuring that MRI scans performed for research purposes are also reviewed by a suitably trained specialist to ensure that lesions incidental tothe purpose ofthe scan are not missed and...
... contributions of data analysis, AM has made substantial contributions to design the manuscript and DA has made substantial contribution to design and has given the final approval ofthe version to be ... lumen between the media and adventitia [10] The presence of severe chest pain of very sudden onset, usually described as tearing and followed from a feeling of impending death, a discrepancy in the ... dilation and insufficiency ofthe aortic valve, pericardial and/ or pleural effusion and finally about a dissection flap, which is the hallmark for the diagnosis ofthe aortic dissection Despite...
... clinical symptoms and signs associated with chondral injuries, and secondly to evaluate outcomes of surgery in athletes with persistent exertion ankle pain caused by chondral lesions tothe talocrural ... dome, lateral, posterior and medial ligaments and lateral malleoli) are systematically examined and probed and all pathology is documented on digital prints and live video The purpose of this ... were identified in 5/26 cases 20/26 scans were retraced and reinterpreted by an unbiased blinded musculoskeletal radiologist who identified chondral injuries in 10/20 cases 3/20 scans presented minor...
... obesity and type two diabetes in school children, and lead to increased rates of cardiovascular and other non-communicable diseases in adulthood To address these issues, SHN programs seek to ... obesity and diabetes, alongside diseases of poverty and social deprivation, such as malnutrition The Caribbean is also challenged as being, according to UNAIDS, the second most HIV-affected region of ... countries, the education sector is already involved in providing health education to staff and students, and a range of health andnutrition services The extent ofthe SHN and HIV response varies between...
... response studies CM participated in the design ofthe study and performed the statistical analysis YD, MAH, CM conceived ofthe study, and participated in its design and coordination and helped to draft ... lines were designated sensitive and 39/91 (43%) cell lines were designated resistant (where sensitive and resistant is defined in the Methods) Discordant values between proliferation and cell death ... These findings are generally consistent with response profiles observed with other Aurora inhibitors [29,31,33] and suggests these disease subtypes can serve as important predictors of response...
... response studies CM participated in the design ofthe study and performed the statistical analysis YD, MAH, CM conceived ofthe study, and participated in its design and coordination and helped to draft ... lines were designated sensitive and 39/91 (43%) cell lines were designated resistant (where sensitive and resistant is defined in the Methods) Discordant values between proliferation and cell death ... These findings are generally consistent with response profiles observed with other Aurora inhibitors [29,31,33] and suggests these disease subtypes can serve as important predictors of response...
... annual production of axis and bud biomass In spite of this stabilisation, the respiratory cost of these tissues continued to rise The characteristics ofthe carbon components of all other studied ... between total shoot area (SA) and SAsun We assumed that SAsun has the same photosynthetic rate as a needle area illuminated by a radiation intensity of Edir/SAsun + Idif , and that SAshade has ... and SA shade, according tothe results of Bosc [2] SAsun (m2) is equal tothe total surface ofthe needle segments that have a face illuminated directly bythe sun SAshade is equal tothe difference...
... mythology, as these examples show: "the goddess Athena, the god Poseidon." Capitalize brand names and trademarks: Jell-O pudding, Kleenex tissues • Danger, Will Robinson Capitalize the names of organizations, ... Head ofthe Class • Abbreviate words associated with addresses or location: I live on Sunset Ave • Abbreviate states Use the official U .S Postal Service (that 'sthe official name ofthe good oP ... M .S or S. M Master of Business Administration M.B.A Medical Doctor M .D Doctor of Philosophy Ph .D Doctor of Divinity D. D Doctor of Dental Surgery D. D .S Registered Nurse R.N Abbreviate time: A.M...
... able to handle this by some ofthe methods already addressed in previous sections As the provider only tells the customer about VCs there is a lack of places to attack Also due tothe fact they ... packets to these addresses However, due tothe address separation of MPLS each incoming packet will be treated as belonging tothe address space ofthe customer Thus it is highly difficult to ... over the backbone The method is simple for the customer and scalable and flexible for the Service Provider This method also allows the Service Provider the ability to provide Internet access to these...
... macroeconomic distortions, misallocation of resources and capital around the world, and greater prudential risks to bank soundness Thus, we call on the IFIs to help countries adopt international standards ... the market s assessment of a jurisdiction s compliance with international regulatory standards translates into its risk assessment and effects the costs for institutions doing business with that ... Payment and Settlement Systems ofthe G10 central banks and other appropriate agencies could explore the technical aspects of this issues and consider possible concrete measures, taking into account...
... realistic messages delivered to people of all ages The use of large-scale media campaigns can address substantial segments of society Also, social marketing should be explored to deliver some ofthe ... sustainable development Thus, ESD also addresses pedagogical processes, the validation of knowledge andthe functioning of education institutions To summarize: - the MDGs provide a set of tangible and ... including financial resources The resources assembled by governments and stakeholders will largely affect the success of national responses tothe DESD The most crucial element tothe Decade s success...
... M2 is co-ordinated to one imidazole and three carboxylate groups The metals in sites M1 and M2 were initially referred to as structural and catalytic metals, respectively [18,26,27], but these ... Co2þ, and Mn2þ Metal specificity depends on both the nature ofthe substrate (i.e glucose or xylose) and whether the enzyme is a class I or class II XI Thermus aquaticus XI, a class I enzyme, isomerizes ... thermostability, whereas class II XIs vary widely in this regard This heterogeneity among class II XIs may arise from the existence of additional salt bridge (s) specific to thermostable class II XIs...
... unpublished materials,22 or to materials published outside the UK and Ireland As such, the downloading and storage by one ofthe copyright depositories of material from a Web site, whether that site ... has to be exposed or offered for acquisition The PCA also criminalises advertisements which suggest that the advertiser distributes or shows indecent photographs of children, or intends to so The ... tothe data controller vs the likelihood of substantial damage or substantial distress to any individual This has not necessarily been the case in other EU countries The issue ofthe impact of...
... markets is essential when performing a sub-sector assessment This includes an analysis of supply and demand, the number andimportanceof buyers and sellers, prices, quality standards, etc Although ... participatory poverty assessment techniques G market analysis and risk assessment stakeholder analysis and conflict assessment G identification and analysis of fish distribution channels gender analysis ... to external shocks and trends (e.g declining fish stocks, seasonal fluctuations in supply and demand), and it is necessary to understand these changes, how the people themselves perceive these...
... in the immunohistochemical assay Correlation between two groups was assessed by Spearman analysis All statistical analyses were performed using spss11.0 software (SPSS, Chicago, IL, USA) A P value ... Hospital, Xi’an, China Patients whose surgical tissue was used for the study signed informed consent All cases of gastric cancer were clinically and pathologically proved The protocols used in ... in the presence of drugs, 20 lL MTT reagent (final concentration gÆL)1) was added to each well, the supernatant was discarded after h, and 150 lL dimethylsulfoxide was added to melt the crystals...
... numbers of fatal cancers caused by radiation exposure due tothe Chernobyl accident — or indeed the impact ofthe stress and anxiety induced bythe accident andthe response to it Small differences ... small differences in the models used to assess risks at low doses can have marked effects on the estimates of additional cancer cases There appears to be some recent increase in morbidity and ... surfaces in urban areas, such as lawns, parks, streets, roads, town squares, building roofs and walls Under dry conditions, trees, bushes, lawns and roofs initially had the highest levels, whereas...
... fragmentation Survival assays (MTT-based assay) and DNA fragmentation ELISAs were performed as described in Materials and methods, andthe data are presented as means SD from at least three independent ... ®tted to a Langmuir : binding model as outlined in Materials and methods The dissociation constant (Kd) was determined from the calculation of kd/ka, where ka is the association rate and kd is the ... the dissociation rate Relative Kd is equal to Kd of IGF-I/Kd of IGF analogue Dashes indicate data inappropriate for assessing association and dissociation rates No detectable binding (ND) was seen...