activation of brain sensorimotor network by somatosensory input in patients with hemiparetic str
Báo cáo khoa học: Insights into the activation of brain serine racemase by the multi-PDZ domain glutamate receptor interacting protein, divalent cations and ATP ppt
... clearly indicates that the binding of the PDZ6 domain by itself is not responsible for the previously reported increase in SR activity [1,12] C Binding of brain SR to recombinant constructs of GRIP ... Next, we decided to analyse the binding of the PDZ6 domain of GRIP to brain SR using recombinant proteins We expressed recombinant brain SR in Escherichia coli using the pCWori vector as previously ... resulted in a two- to three-fold increase [12] Finally, Golga3 binds to the first 66 amino acids of brain SR and, remarkably, this binding also results in an increased d-serine synthesis However, activation...
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Báo cáo y học: " Liver and brain abscess caused by Aggregatibacter paraphrophilus in association with a large patent foramen ovale: a case report" pps
... multiple brain abscesses by permitting infected material to bypass the lungs and enter the systemic circulation The foramen ovale serves as a shunt during intrauterine life and occludes after birth with ... Ormond Street Hospital for Children, London, UK for identification of isolates Author details Department of Medicine, Hinchingbrooke Health Care NHS Trust, Hinchingbrooke Hospital, Hinchingbrooke ... A CT scan of the head with contrast performed on day 52 revealed multiple brain abscesses: a ringenhancing lesion in the left occipital lobe and a nonenhancing low attenuation lesion in the right...
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Báo cáo y học: "A comparative analysis of antibody repertoire against Staphylococcus aureus antigens in Patients with Deep-Seated versus Superficial staphylococcal Infections"
... response against PG in some of the patients with deep infection might be due to impaired immunity of advancing age, poor expression of virulence determinants by the infecting strain or changes in the ... IgG-HRP conjugate diluted in PBST containing 1% BSA was added and incubated at 37°C for h After washing 100µl of substrate containing 10mg of orthophenylene diamine (OPD) in 25ml of citrate-phosphate ... the type of infection [22] In order to compare the whole cell protein profile of S aureus strains associated with deep-seated and superficial infection, whole cell lysates of isolates of both...
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báo cáo hóa học: "Validity and reliability of a new, short symptom rating scale in patients with persistent atrial fibrillation" pot
... short instrument is a reliable and valid instrument for assessing symptoms in patients with AF Advantages, in addition to being AF specific, are that it can be included in a routine clinical ... of the Italian translation of the gastrointestinal symptom-rating scale and quality of life in reflux and dyspepsia questionnaire in patients with gastrooesophageal reflux disease Clin Drug Investig ... validity involves demonstrating that theoretically related dimensions of an instrument are highly correlated and was examined by correlating the items with SF-36 domains To gain additional information,...
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báo cáo hóa học: " The minimal important difference of the hospital anxiety and depression scale in patients with chronic obstructive pulmonary disease" pot
... specifying the patient-important difference that investigators want to detect To find a difference of 1.5 points at a significance level of 0.05 and with a power of 80% and assuming a SD of points ... shows that the minimal important of the HADS is around 1.5 points in COPD patients corresponding to a change from baseline of around 20% This estimate is informed by both anchor- and distribution-based ... still lacking to provide strong recommendations However, the treatment of depression in disease such as COPD will be increasingly important In trials using the HADS the MID estimate of 1.5 points...
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báo cáo hóa học: " Improvement of quality of life, anxiety and depression after surgery in patients with stress urinary incontinence: Results of a longitudinal short-term follow-up" docx
... including stress urinary incontinence (SUI), urge incontinence, mixed incontinence, neurogenic incontinence, functional incontinence or overflow incontinence [8] This study is restricted to patients ... the domains of physical well-being, social well-being, emotional well-being and functional well-being Incontinence Quality of Life Instrument (I-QOL) The Incontinence Quality of Life Instrument ... patients with SUI The majority of patients suffering from UI have weakened pelvic floor muscles In the case of SUI an increase in intraabdominal pressure (induced by activities such as coughing,...
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báo cáo hóa học: " Evaluation of the reliability and validity of the Medical Outcomes Study sleep scale in patients with painful diabetic peripheral neuropathy during an international clinical trial" pot
... consists of a single-item with an 11-point numerical rating scale, ranging from (pain does not interfere with sleep) to 10 (pain completely interferes with sleep) that allows the calculation of a ... daily pain diary at visit (V1) and had to record pain during the next days of the baseline phase The diary consists of a single item with an 11-point numeric self-administered rating scale ranging ... weekly mean sleep interference score and the weekly mean pain score at baseline were used to define groups of patients differing in severity Since patients had to have pain at baseline to qualify...
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báo cáo hóa học: " Development and validation of the insulin treatment appraisal scale (ITAS) in patients with type 2 diabetes" docx
... flexible Fear of needle injection Insulin will increase the risk of hypoglycaemia Insulin will improve health Insulin will cause weight gain 10 Insulin will be demanding to administer 11 Insulin means ... enjoy 12 Insulin means my health will deteriorate 13 Injecting insulin is embarrassing 14 Injecting insulin is painful 15 It is difficult to always inject insulin correctly 16 Insulin makes it ... (ITAS) in both insulin naïve and insulin-treated type diabetes patients Factor analyses suggest a simple twofactor structure, with items pertaining to a positive and a negative appraisal of insulin...
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Báo cáo hóa học: " Validity of gait parameters for hip flexor contracture in patients with cerebral palsy" pot
... (responsiveness) Page of the key kinematic variables The kinetic data including time of crossover in the hip flexion-extension moment and the power burst of hip flexor in the late stance were obtained The ... The kinetic variable, including the time of crossover in the hip flexion-extension moment and the power burst of the hip flexor in late stance, were similar in the patients and controls In this ... parameters in patients group Pre-operative minimum TOC, time of cross over in hip flexion/extension moment; H3, late swing power burst in hip joint flexion/extension power; HFI, hip flexor index;...
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báo cáo hóa học:" Structural ambiguity of the Chinese version of the hospital anxiety and depression scale in patients with coronary heart disease" doc
... artifactual of the original translation process, which may also explain inconsistencies between the underlying factor structure of the instrument between Mandarin-speaking Chinese CHD patients in the ... angina The finding of high proportions of Chinese CHD patients screening positive with anxiety and depression using the HADS is consistent with previous studies conducted in China or in western ... Xi'an province of China Mandarin is spoken Due to the pictorial nature of Chinese writing, both Cantonese and Mandarin-speaking Chinese would be able to read the Chinese version of the HADS In Europe,...
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báo cáo hóa học:" Development and validation of the insulin treatment appraisal scale (ITAS) in patients with type 2 diabetes" pdf
... flexible Fear of needle injection Insulin will increase the risk of hypoglycaemia Insulin will improve health Insulin will cause weight gain 10 Insulin will be demanding to administer 11 Insulin means ... enjoy 12 Insulin means my health will deteriorate 13 Injecting insulin is embarrassing 14 Injecting insulin is painful 15 It is difficult to always inject insulin correctly 16 Insulin makes it ... (ITAS) in both insulin naïve and insulin-treated type diabetes patients Factor analyses suggest a simple twofactor structure, with items pertaining to a positive and a negative appraisal of insulin...
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báo cáo hóa học:" Validity and reliability of a new, short symptom rating scale in patients with persistent atrial fibrillation" ppt
... short instrument is a reliable and valid instrument for assessing symptoms in patients with AF Advantages, in addition to being AF specific, are that it can be included in a routine clinical ... of the Italian translation of the gastrointestinal symptom-rating scale and quality of life in reflux and dyspepsia questionnaire in patients with gastrooesophageal reflux disease Clin Drug Investig ... validity involves demonstrating that theoretically related dimensions of an instrument are highly correlated and was examined by correlating the items with SF-36 domains To gain additional information,...
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báo cáo khoa học: "Analysis of the expression pattern of the BCL11B gene and its relatives in patients with T-cell acute lymphoblastic leukemia" doc
... other four genes of interest in the healthy controls Discussion Increasing numbers of translocations involving the BCL11B locus [8,10,11] or high levels of BCL11B mRNA expression in most T-ALL cases ... the release of mitochondrial factors, some of which depend on the action of caspases BCL2L1 may inactivate caspase-8 by decreasing death-inducing signaling complex (DISC) formation in the plasma ... participate in the same protein-protein interactions, along with competitive downstream target proteins BCL2L1 (Bcl-xL) normally interferes with the mitochondrial programmed cell death pathway by sequestering...
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Báo cáo y học: " Systematic monitoring of needs for care and global outcomes in patients with severe mental illness" ppsx
... almost never trained in its use The actual knowledge of the instructions is poor and raters are often misled by confusingly defined anchors In addition, GAF instructions may be incomplete [16] ... excluded Years since baseline Years in care since baseline was an independent variable in most of the analyses (see below) It was calculated by subtracting the baseline date (in days) from the ... committees in Maastricht, Utrecht and Groningen have confirmed that by law this type of data collection is not in their remit as long as patients are aware of the purpose (including the use of their...
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báo cáo khoa học: " Influence of lip closure on alveolar cleft width in patients with cleft lip and palate" ppt
... continuation of the line marking the crest of the ridge a days old, mm alveolar cleft width b before lip closure at the age of months, after treatment with feeding plate c before closure of soft ... closure at the age of months, after treatment with feeding plate c before closure of soft palate at the age of 10 months, soft tissues in contact Eichhorn et al Head & Face Medicine 2011, 7:3 http://www.head-face-med.com/content/7/1/3 ... grafting of the alveolar cleft, if desired The use of calvarian bone instead of bone from the iliac crest or mandible seems to be a promising alternative in bridging narrow alveolar defects [22] In...
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báo cáo khoa học:" Measurement properties of physical function scales validated for use in patients with rheumatoid arthritis: A systematic review of the literature" pps
... JC, et al: A cross sectional assessment of health status instruments in patients with rheumatoid arthritis participating in a clinical trial Minocycline in Rheumatoid Arthritis Trial Group J Rheumatol ... of the items for assessing physical functioning of patients with RA [19] The relevance of a scale was rated positively if all items of a scale could be linked to ICF codes that are included in ... assessment of the content validity of included generic scales for assessing physical functioning of patients with RA The SF-36 PF scale is probably the most frequently used generic scale in patients with...
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Báo cáo y học: "The effects of long-acting bronchodilators on total mortality in patients with stable chronic obstructive pulmonary disease" pdf
... examined the relationship of tiotropium, a long-acting anticholinergic, as well as formoterol and salmeterol, which are long-acting beta-2 agonists, by themselves or in combination with an inhaled ... salmeterol/fluticasone in patients with stable COPD in which total mortality was reported We supplemented the electronic search by reviewing the bibliographies of selected articles, examining review articles ... drug to drug interactions [12] The collective results of inhaled corticosteroid/long-acting beta-2 agonist combination are summarized in figure In total, there were 269 deaths in the inhaled corticosteroid...
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Báo cáo y học: "Connective tissue growth factor promotes articular damage by increased osteoclastogenesis in patients with rheumatoid arthritis" doc
... high expression of the integrin αVβ3, which binds to a variety of extracellular matrix proteins including vitronectin, osteopontin, and bone sialoprotein Arg-Gly-Asp (RGD)-containing peptides, ... could interact with integrin αVβ3 in other types of cells, however, it has not been shown to our knowledge that integrin αVβ3 on the osteoclasts interact with CTGF Furthermore, blocking of the integrin ... role of CTGF in the development of bone destruction in patients with RA and suggested a mechanism explaining the efficacy of antiTNF-α antibodies in the prevention of bone destruction in RA The...
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Báo cáo y học: " Characterization of the bronchodilatory dose response to indacaterol in patients with chronic obstructive pulmonary disease using modelbased approaches" ppt
... largely independent of disease severity Finally, it is instructive to place the findings of this analysis in the context of the GOLD classification of COPD severity [19] For this purpose, patients ... that included assessment of trough FEV1 and had a duration of at least 14 days Indacaterol was compared with formoterol in two studies, with salmeterol in four studies and with tiotropium in one ... panel) Visual inspection of the indacaterol data points indicated that with increasing dose the response asymptotically approached a maximum plateau The majority of study results for doses of 75 μg...
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Báo cáo y học: "Macrophage migration inhibitory factor enhances osteoclastogenesis through upregulation of RANKL expression from fibroblast-like synoviocytes in patients with rheumatoid arthriti" doc
... immunohistochemical staining to compare the expression of MIF and RANKL in synovial tissues More intense staining of MIF and RANKL was observed in synovium from patients with RA compared with synovium from patients ... protein 1.69 ± 0.3 mg/dL Page of 13 To determine the relation of MIF with sRANKL, the concentrations of sRANKL and MIF in synovial fluid from RA patients were measured using sandwich ELISA In RA patients, ... one hour followed by incubation with 3,3"-diaminobenzidine (Dako, Glostrup, Denmark) for five minutes The sections were counterstained with hematoxylin Samples were photographed with an Olympus...
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