a genealogical and heraldic history of the commoners of great britain volume 2
Revised version for the consideration of Contact Committee of the Heads of the SAIs of the European Union docx
... structure of some “courts of audit”. Nevertheless, there are attributes that are applicable to all SAIs and to all audits. Among these are the characteristics of quality and the phases of the audit ... collectively has the appropriate capabilities, competence and time to perform the audit in accordance with professional standards and applicable regulatory and legal requirements, and to enable the issuance ... managers must also be vigilant. It is important that the factual basis of final descriptions, analyses and recommendations is accurate. The report should be objective and balanced and have a...
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Tài liệu Commodore Barney''''s Young Spies A Boy''''s Story of the Burning of the City of Washington docx
... American army and navy, save Joshua Barney; but a word against him was to the old man much as a red flag is to a bull, and in a twinkling the trouble began." ;The man who says aught against the ... took a hand, standing close by the old man's side.As I aimed a blow at Elias I saw, out of the tail of my eye, Jerry drop his meal as he came forward at fullspeed, and at almost the same ... pacesdistant from the three.I felt, rather than saw, that Darius sprang forward; there was a dull thud, a groan, and a cry from one of the other Britishers which told that the battle was on, but the...
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Báo cáo khoa học: ATP-binding domain of heat shock protein 70 is essential for its effects on the inhibition of the release of the second mitochondria-derived activator of caspase and apoptosis in C2C12 cells potx
... inhibition of H 2 O 2 -induced activation of caspases-9 and -3 and apoptosis. (A) The effects of HSP70 and its deletion mutant proteins on the acti-vation of caspases-9 and -3 were analyzed. Cells ... cellularchanges. We demonstrate that HSP70 over-expression markedly inhibited the release of Smac and prevented the activation of caspases-9 and -3 and apoptosis in C2C 12 cells under H 2 O 2 treatment. ... prevents caspase-3 and stress-activated protein kinase ⁄ Jun kinase (JNK)activation [18] and mitochondrial depolarization [19],blocks apoptosome formation and activation of caspase-9 [20 ], and inhibits...
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Báo cáo Y học: Chimeric receptor analyses of the interactions of the ectodomains of ErbB-1 with epidermal growth factor and of those of ErbB-4 with neuregulin potx
... and C-terminal parts of the ligand are cross-linked to domainsI and III, respectively, of the receptor [19 ,22 ]. The b sheet of EGF may bind to domain I of ErbB-1, and the other surface of the ligand binds ... protein loading.Ó FEBS 20 02 Ligand specificities of ErbB-1/ErbB-4 chimeras (Eur. J. Biochem. 26 9) 23 27 of the EGF-like motif of the ligand have already beencharacterized as high and low affinity ... Each of these receptorshas an extracellular region, a single transmembrane region, and a cytoplasmic sequence containing a tyrosine kinasedomain and a C-terminal tail. The extracellular region...
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Tài liệu THE DISCOVERY OF THE SOURCE OF THE NILE docx
... Generally speaking, they live upon the coast, and call themselves Diwans, headsmen, and subjects of the Sultan Majid; but they no sooner hear of the march of a caravan than they transpose their ... £5000 down at once, I would return to Zanzibar at the end of the year, March to Kaze again, and make the necessary investigations of the Victoria lake. Although, in These are a few of the more ... a peculiar manner, laughs and yawns again, and, saying it is time to go, walks off in the same way as he came. At other times when he is called, he will come sucking away at the spout of a...
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The Discovery of the Source of the Nile docx
... back to Kaze, another to form a reserve force at Mdaburu,on the east flank of the wilderness, and a third, headed by Snay and Jafu, to attack Mzanza. At the first onsetSnay and Jafu carried everything ... Mdaburu, and that again was cut off from their caravans at Kanyenye by the Mzanza people, and in fact all the Wagogo; so they hoped at least I would not forsake them, which they heard I was going ... bidding Sheikh Saidtake all our letters and specimens back to the coast as soon as the road was found practicable, set out on the march northwards with Grant and Baraka, and all the rest of my men...
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Tài liệu THE HISTORY OF THE RISE, PROGRESS, AND ACCOMPLISHMENT OF THE ABOLITION OF THE SLAVE-TRADE pdf
... first place, they have enabled those who came after them, and who took an active interest in the same cause, to state the great authority of their opinions and of their example. They have enabled ... cannot name any individual who took a part in this cause till between the years 1670 and 1680; for in the year 1640, and for a few years afterwards, the nature of the trade and of the slavery ... proposal with the humane and charitable spirit of the bishop of Chiapa. But it is probable he believed that a code of laws would soon be established in favour both of Africans and of the natives...
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Tài liệu History and Ecclesiastical Relations of the Churches of the Presbyterial Order at Amoy, China doc
... doctrinal standards, and theyexplain them in the same manner; they have the same form of Church government, and their officers arechosen, and set apart in the same way; they have the same order of ... office-bearers, and all the incipient steps of the organization of the Church from among the heathen. The Constitution was made for the government of a Church already organized and matured, and in America; ... two-thirds of an integral part in America, and one-third of an integral part in England? No. The whole is a fallacy. Each individual Church there is an integral part of the whole of them. All together,...
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A Joint Publication of the Office of the Attorney General and the Department of Business and Economic Development docx
... Occupational Safety and Health Plan of the State of Maryland and has authorized the State to be the enforcement agency. The Maryland Occupational Safety and Health Act approach is preventive-regulatory, ... by guaranteeing at least a portion of the State’s financial assistance or making a loan or grant for the project in an amount equal to at least 10 percent of the State's financial assistance ... commissioned salespersons, outside salespersons, professional and administrative employees, and supervisory and managerial employees at or above a certain salary level. Both Maryland and federal law...
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Báo cáo khoa học: The oxidative effect of bacterial lipopolysaccharide on native and cross-linked human hemoglobin as a function of the structure of the lipopolysaccharide A comparison of the effects of smooth and rough lipopolysaccharide ppt
... to an increase in the rate of the initial fast phase, i.e. oxidation of the a chains. The rates of oxidation are reduced in the presence of chelators of heavy metal cations in most cases. An ... anion, as wassuggested by Tsuruga and Shikama [21 ] to explain the increase in oxidation rate of the a chains in the ab dimer. Ithad been demonstrated earlier by Wallace et al. [26 ] thatnucleophiles ... 3A. The rate of auto-oxidation of cross-linked Hb was greaterthan that of Hb A 0,both in the presence and absence of EDTA, as has been observed previously [17]. In addition, the rates of auto-oxidation...
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By Pike and Dyke: A Tale of the Rise of the Dutch Republic pdf
... Europe can stand against their pikemen. If the Low Countries, whichnumber as many souls as we, cannot make a stand against them with all their advantages of rivers, and swamps, and dykes, and fortified ... murdered mygrandfather and uncles and one of my aunts; they have shot away my father's leg, and would have taken hislife had he not escaped out of their hands; so that what was before a longing ... him a pot of beer, toascend the ramparts and fire two pieces of artillery at the Spanish ships. The offer was accepted, and the man ran up to the ramparts and discharged the guns. A sudden panic...
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Báo cáo Y học: Electrostatic properties of the structure of the docking and dimerization domain of protein kinase A IIa doc
... [22 ,23 ] were used in the calculations, withfocusing grids of 2. 5, 1 .25 , 0.5, and 0 .25 A ˚. The parameterset of charges and van der Waals radiiPARSE [24 ], dielectricconstants of 78.4 and 20 .0, ... between the donor and acceptor atoms and their relative orientation,but also the observation of unusual pK a values attributed toside chain interactions. A dynamic character of the two sidechains ... Phe31,Tyr35 and Phe36 and contacts involving the side chains of Leu 12, Val20, Leu28, Val29, Val33, Thr37 and Leu39, areobserved in the hydrophobic core (Fig. 4A) . An additionalTable 2. RIIa D/D structure...
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