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22 cip4 see international cooperation for the integration of processes in prepress press and postpress

Báo cáo y học:

Báo cáo y học: " A multi-center, randomized, double-blind, parallel, placebo-controlled trial to evaluate the efficacy, safety, and pharmacokinetics of intravenous ibuprofen for the treatment of fever in critically ill and non-critically ill adults" pdf

Báo cáo khoa học

... required for the first time in of 224 ibuprofentreated patients (3 percent) and 13 of 231 placebo-treated patients (6%, P = 0.11) Gastrointestinal bleeding was reported in nine patients in the ibuprofen ... For secondary endpoints, 21 of 30 (70%) of subjects in the 200 mg IV ibuprofen group, and 19 of 31 (61%) of subjects in the 100 mg IV ibuprofen group, compared to of 28 (32%) of the placebo group ... participants in the order they were enrolled, based upon stratification The randomization block size was four The randomization block size was not revealed during the course of the study to assist in maintaining...
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Báo cáo y học:

Báo cáo y học: " Updating the evidence for the role of corticosteroids in severe sepsis and septic shock: a Bayesian meta-analytic perspective" pot

Báo cáo khoa học

... results of the Corticosteroid Therapy of Septic Shock (CORTICUS) [8] study, clinical equipoise remained for the issues of adreno-corticotrophin (ACTH) administration, cortisol testing, and the therapeutic ... metric, the intersection of the (meta)regression line with the line of null effect (’cross-over’ point) occurred for age at 62 years and for control-arm mortality at 44% Complications of therapy The ... forest plot representation of the effect The vertical straight line denotes null effect (odds ratio (OR) = 1) The individual points denote the OR for each study and the lines on either side the...
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Bioanalytical strategies for the quantification of xenobiotics in biological fluids and tissues 1

Bioanalytical strategies for the quantification of xenobiotics in biological fluids and tissues 1

Cao đẳng - Đại học

... liquid–liquid and solid phase extractions can be applied for solid samples However they require tedious steps including mincing, shredding, grinding, pulverizing and pressurizing, to render the sample and ... directly into the environment [13, 14] The major routes by which the aforementioned environmental toxicants enter the body are through the skin, the lungs, and the gastrointestinal tract and they ... important role in the disease diagnostics, since the non-biodegradable nature of most metals makes them of the most insidious pollutants The monitoring of trace metals in humans is therefore very...
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Bioanalytical strategies for the quantification of xenobiotics in biological fluids and tissues 2

Bioanalytical strategies for the quantification of xenobiotics in biological fluids and tissues 2

Cao đẳng - Đại học

... [5-8] Therefore, determining the level of estrogens in these body fluids would be very important for the study of their roles in the carcinogenesis of ovarian and breast cancer The role of estrogen ... numbers of clinical samples is required for a better understanding of the role of these compounds in the progression of ovarian cancer From the results obtained using the µ-SPE technique, we infer ... concentrations of each of the analytes The extraction results are shown in Table 2.2; for µ-SPE, the relative recoveries, which is defined as the ratio of GC peak areas for the analytes in the spiked...
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Bioanalytical strategies for the quantification of xenobiotics in biological fluids and tissues 3

Bioanalytical strategies for the quantification of xenobiotics in biological fluids and tissues 3

Cao đẳng - Đại học

... present in those samples In a biplot, the length of the lines approximates the variances of the variables The longer the line, the higher is the variance Inferring from Figure 3.7, 3-nitroaniline ... amine, 3-bromoaniline were prominent in most of the benign samples The clinical importance of their elevated levels in malignant samples in terms of their roles in benign to malignant transformation ... important in the view that, the synergic effect of these chemicals could provide significant influence in the malignancy of the tumor On the other hand, benign samples are greatly scattered in the...
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Bioanalytical strategies for the quantification of xenobiotics in biological fluids and tissues 4

Bioanalytical strategies for the quantification of xenobiotics in biological fluids and tissues 4

Cao đẳng - Đại học

... 310˚C min-1 and 5˚C min-1 to 320˚C (hold for 10 min) µL of the sample was injected into the GC-MS in splitless mode and the total GC-MS analysis time was 55.00 SIM mode employed for the set of target ... their source of origin [1, 2] The half-life of PCBs in the blood ranges from < to > 10 years, depending on the congener [3, 4] PCBs can be measured in most of the general population because of ... because of their environmental ubiquity and persistence For instance, in a report of a large and statistically representative sampling of 1,800 individuals 12 years of age and older from the U.S...
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Bioanalytical strategies for the quantification of xenobiotics in biological fluids and tissues 5

Bioanalytical strategies for the quantification of xenobiotics in biological fluids and tissues 5

Cao đẳng - Đại học

... has increased in the recent decade, not only the trace metals but the heavy metals as well The study of the role of the trace elements has been emphasized in the search for the possible causes of ... research for the determination of trace metal status of individuals and groups [9-11] Nonetheless, in the case of ovarian tumor, both benign and malignant ovarian cyst fluids are good source of information ... impacts the action of several drugs and toxins via its conjugation in the liver An increase in the incidence of hypertension has been observed following lead exposure in humans [8] In the present...
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Bioanalytical strategies for the quantification of xenobiotics in biological fluids and tissues 6

Bioanalytical strategies for the quantification of xenobiotics in biological fluids and tissues 6

Cao đẳng - Đại học

... withdrawn into the GC syringe and the needle of the syringe was inserted into hollow fibre to about 0.2 cm of the tip of the syringe needle was covered by it The hollow fibre was then dipped into the ... discarded) Using the same syringe, µL of BSTFA was withdrawn, making the total volume in the GC syringe µL The entire µL was injected into the GC-MS for injection port derivatiztion and analysis ... sample and derivatization agent were retained in the injection port for min) Since the injection port is heated to high temperature (300ºC) and pressurized, the holding time of would allow the estrogens...
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Bioanalytical strategies for the quantification of xenobiotics in biological fluids and tissues 7

Bioanalytical strategies for the quantification of xenobiotics in biological fluids and tissues 7

Cao đẳng - Đại học

... the stacking gel, causing the proteins to be compressed and ‘stacked’ into a tight band, less than mm thick, at the running front of glycine before it reaches the resolving gel Once the running ... silver ions bind to the proteins in the gel, and are reduced to metallic silver, causing the protein bands in the gel to be visualized [21] This method forms the basis of the Silver Stain Plus kit ... completely and then incubated in a humid chamber at room temperature for a specified period (60 min, 30 min) of time The amount of antibody binding depends on several factors, including degree of washing...
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Bioanalytical strategies for the quantification of xenobiotics in biological fluids and tissues 8

Bioanalytical strategies for the quantification of xenobiotics in biological fluids and tissues 8

Cao đẳng - Đại học

... samples, they were relatively mere highly correlated in the malignant group than in the benign groups With the aid of PCA, their trend in the two groups of samples is compared and individual and compound ... relevant to the objective of the study Further, the cyst fluids were studied for their and inorganic trace element levels by applying a combination of high throughput analytical strategies The accumulation ... pertinent to the tumor, such as 164 Chapter carcinogens and EDCs Most of the analytes chosen are abundant in the environment, and in one way or another, available to human exposure It includes the...
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International cooperation for the conservation and sustainable and fair use of biodiversity

International cooperation for the conservation and sustainable and fair use of biodiversity

Tổng hợp

... conservation and sustainable use of biodiversity, the multilayered demanding nature of biodiversity, and the challenging international cooperation, motivate my research on aspects of international cooperation ... background for the further analysis In addition, I outline and motivate in more detail the rationale for biodiversity conservation and its sustainable and fair use and thereby for investigating aspects ... picture of international cooperation for the conservation and sustainable and fair use of biodiversity as a foundation for analysing important aspects of it in detail in the next chapters 2.2 The...
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Chinas rise in the diamond market an international explanation for the resurgence of conflict diamonds

Chinas rise in the diamond market an international explanation for the resurgence of conflict diamonds

Tổng hợp

... space   of   both   the   diamond  mining and  producing  countries   The  diamonds  industry  involves the processes of  mining,  sorting,  cutting   and  polishing,  manufacturing and  retail .22 ... Chapter  2:  China,  Africa and the  diamond  link   Redefining  China’s  Involvement in  Africa   If  we  are  to  understand  China’s  role in the  African  continent in the  twenty-­‐first ... between   these   institutions,   on   the   one   hand,   and   between  them and  African  institutions,  on the  other,  are  shaping and  reshaping   the   Sino-­‐African   relationship   and...
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INTERNATIONAL CONVENTION FOR THE SAFETY OF LIFE AT SEA, 1974

INTERNATIONAL CONVENTION FOR THE SAFETY OF LIFE AT SEA, 1974

Tài liệu khác

... control giving rise to intervention of any kind, the officer carrying out the control shall inform the Consul of the State whose flag the ship is entitled to fly in writing forthwith of all the circumstances ... coal from interfering with the closing of watertight bunker doors (e) Within spaces containing the main and auxiliary propelling machinery including boilers serving the needs of propulsion and all ... receive the special consideration of the Administration Regulation 14 Openings in the shell plating below the margin line (a) The number of openings in the shell plating shall be reduced to the minimum...
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Báo cáo y học:

Báo cáo y học: "Thioglycosides as inhibitors of hSGLT1 and hSGLT2: Potential therapeutic agents for the control of hyperglycemia in diabetes"

Y học thưởng thức

... metabolized in the intestine [27] Therefore, a chemical reaction to convert the substance in its active form, after intestinal absorption like in the case of O-glucosides, is not necessary In addition, ... at 460 and 580 nm After a 20 sec baseline reading, 0.1 ml of PBS containing 10 µM of the compound investigated was added, and the fluorescence signal was recorder for 40 sec The change in fluorescence ... phosphate-buffered saline (PBS; Invitrogen, Karlsruhe, Germany) and then incubated with 0.1 ml of a solution containing µM CC2-DMPE and 0.02% pluronic acid in PBS After in- cubation in the dark for 30 at...
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Tài liệu OUTLINES OF DAIRY BACTERIOLOGY A CONCISE MANUAL FOR THE USE OF STUDENTS IN DAIRYING docx

Tài liệu OUTLINES OF DAIRY BACTERIOLOGY A CONCISE MANUAL FOR THE USE OF STUDENTS IN DAIRYING docx

Điện - Điện tử

... as the determination of culture characteristics; in fact, the two must go hand in hand The examination reveals not only the form and size of the individual germs, but the manner in which they ... on the surface, or in the depth of the culture medium These patches are called colonies and are composed of an almost infinite number of individual germs, the result of the continued growth of ... the farm and the degree of care which is exercised while the product is in the hands of the milk producer is the determining factor in the course of bacterial changes involved This of course...
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Tài liệu Guideline on Best Practice for the Audit of Risk in Public/Private Partnership (PPP) docx

Tài liệu Guideline on Best Practice for the Audit of Risk in Public/Private Partnership (PPP) docx

Kế toán - Kiểm toán

... 2: Risks facing the SAI F examining the process and the results G identifying worthwhile lessons H following up their work 17 Part 2: Risks facing the SAI F Examining the process and the results ... the range of skills needed in monitoring and managing the relationship, and consider how to retain or access such skills Provide for these arrangements in the partnership terms Sources of information ... alert to the possibility of corruption and money laundering throughout the life of the partnership 11 In auditing how risks are managed in the course of setting up a PPP, and ensuring that there...
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Báo cáo khoa học: New evidence for the role of calcium in the glycosidase reaction of GH43 arabinanases pot

Báo cáo khoa học: New evidence for the role of calcium in the glycosidase reaction of GH43 arabinanases pot

Báo cáo khoa học

... activity of BsArb43B Furthermore, to determine whether the role of the calcium is structural, thermal shift assays were performed to determine the Tm of the protein in the presence and absence of the ... observed either between residues located in blades IV and V and the C-terminal domain or between the hairpin that joins blades IV and V and the C-terminal domain (Fig and Table S1) The apolar interactions ... the catalytic domain, and is located between blades II and III on one side and blades V and I on the other Structural comparison of the BsArb43B binding cleft with the binding cleft of the other...
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