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Part 1 book “Gynecologic oncology clinical practice and surgical atlas” has contents: Epidemiology of gynecologic cancers, clinical trials, and statistical considerations, genetics and biology of gynecologic cancers, diagnostic modalities, cervical cancer, endometrial hyperplasia and cancer, uterine sarcomas, gestational trophoblastic disease,… and other contents.
NOTICE Medicine is an ever-changing science As new research and clinical experience broaden our knowledge, changes in treatment and drug therapy are required The authors and the publisher of this work have checked with sources believed to be reliable in their efforts to provide information that is complete and generally in accord with the standards accepted at the time of publication However, in view of the possibility of human error or changes in medical sciences, neither the authors nor the publisher nor any other party who has been involved in the preparation or publication of this work warrants that the information contained herein is in every respect accurate or complete, and they disclaim all responsibility for any errors or omissions or for the results obtained from use of the information contained in this work Readers are encouraged to confirm the information contained herein with other sources For example and in particular, readers are advised to check the product information 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content of any information accessed through the work Under no circumstances shall McGraw-Hill and/or its licensors be liable for any indirect, incidental, special, punitive, consequential or similar damages that result from the use of or inability to use the work, even if any of them has been advised of the possibility of such damages This limitation of liability shall apply to any claim or cause whatsoever whether such claim or cause arises in contract, tort or otherwise Dedication This textbook and all of our professional accomplishments would not be possible without the enduring support of our families We dedicate this effort to our understanding spouses, Scott, Michelle, and Cathy; our high-spirited children, Matthew and Jocelyn Karlan, Jackson, Chloe, and Haley Bristow, Jason, Lucas, and Evan Li; and to our loving parents, Beverly and Stanley Young, Lynn and Lonnie Bristow, and Chien and Marian Li, who raised us with passions for caring and eternal learning Our many teachers and mentors provided us with the knowledge and skills to care for women with gynecologic cancers and motivated us to continue pushing the therapeutic envelope until cures are within our grasp Our colleagues—physicians, scientists, nurses, and other professionals—work shoulder to shoulder with us, and support, challenge, motivate, and make us laugh when it is most needed And most importantly, this book is dedicated to the legions of women with gynecologic cancer, both living and in our memories, who have taught us tenacity, selflessness, and courage We hope that this text will educate future generations of clinicians and scientists whom we can enlist on our journey to end cancer as a threat to women Contents Contributors Preface FUNDAMENTAL TOPICS Epidemiology of Gynecologic Cancers, Clinical Trials, and Statistical Considerations Wendy R Brewster and Krishnansu S Tewari Genetics and Biology of Gynecologic Cancers Douglas A Levine Diagnostic Modalities David Starks, Bin Yang, and Peter G Rose DISEASE SITES Preinvasive Disease of the Lower Genital Tract Levi S Downs Jr and Jori S Carter Cervical Cancer Angela J Ziebarth, Kenneth H Kim, and Warner K Huh Endometrial Hyperplasia and Cancer David A Iglesias, Marilyn Huang, Pamela T Soliman, Bojana Djordjevic, and Karen H Lu Uterine Sarcomas Gary S Leiserowitz Gestational Trophoblastic Disease Diljeet K Singh Vulvar Cancer Mark Milam and Charles F Levenback 10 Vaginal Cancer William J Lowery, Junzo Chino, and Laura J Havrilesky 11 Management of the Adnexal Mass Ritu Salani and Christa Nagel 12 High-Grade Serous Carcinomas of the Ovary, Fallopian Tube, and Peritoneum David E Cohn and Ronald D Alvarez 13 Epithelial Ovarian Cancers: Low Malignant Potential and Non-Serous Ovarian Histologies Gregory P Sfakianos, Angeles Alvarez Secord, and Ie-Ming Shih 14 Germ Cell and Sex Cord-Stromal Ovarian Cancers Susan C Modesitt and Jubilee Brown 15 Breast Cancer and Related Diseases Catherine M Dang and M William Audeh 16 Cancer in Pregnancy Malaika Amneus and Christine H Holschneider 17 Metastases to the Gynecologic Tract S Diane Yamada and Nita K Lee III CLINICAL MANAGEMENT TOPICS 18 Perioperative and Critical Care Renata Urban and Lee-may Chen 19 Principles of Radiation Therapy Wui-Jin Koh and Lindsay R Sales 20 Principles of Chemotherapy Ursula A Matulonis 21 Targeted Therapy and Immunotherapy Robert L Coleman and Paul J Sabbatini 22 Integrative Oncology, Quality of Life, and Supportive Care Diljeet K Singh and Vivian E von Gruenigen 23 Surgical Instrumentation and Sutures John C Elkas and Addie Alkhas IV SURGICAL ATLAS 24 Ovarian and Fallopian Tube Procedures Eric L Eisenhauer and Jeffrey M Fowler 25 Uterine Procedures John O Schorge and David M Boruta II 26 Cervical Procedures Danielle Vicus and Allan Covens 27 Vulvar and Vaginal Excisional Procedures Mark A Morgan, Sarah H Kim, and Sameer A Patel 28 Lymphadenectomy Lisa A dos Santos and Nadeem R Abu-Rustum 29 Staging Procedures Summer B Dewdney and Matthew A Powell 30 Cytoreductive Procedures Edward J Tanner III, Fady Khoury-Collado, and Dennis S Chi 31 Minimally Invasive Surgery Pedro T Ramirez, Michael Frumovitz, and Pedro F Escobar 32 Pelvic Exenteration A Total Pelvic Exenteration Barbara A Goff and Howard G Muntz B Urinary Diversions Thomas C Krivak and Paniti Sukumvanich trimester of pregnancy: a follow-up study Magn Reson Imaging 2004;22(6):851-854 19 Clements H, Duncan KR, Fielding K, Gowland PA, Johnson IR, Baker PN Infants exposed to MRI in utero have a normal paediatric assessment at months of age Br J Radiol 2000;73(866):190-194 20 Webb JA, Thomsen HS, Morcos SK The use of iodinated and gadolinium contrast media during pregnancy and lactation Eur Radiol 2005;15(6):12341240 21 Fenig E, Mishaeli M, Kalish Y, Lishner M Pregnancy and radiation Cancer Treat Rev 2001;27(1):1-7 22 Kal HB, Struikmans H Radiotherapy during pregnancy: fact and fiction Lancet Oncol 2005;6(5):328-333 23 Han B, Bednarz B, Xu XG A study of the shielding used to reduce leakage and scattered radiation to the fetus in a pregnant patient treated with a 6-MV external X-ray beam Health Phys 2009;97(6):581-589 24 Woo SY, Fuller LM, Cundiff JH, et al Radiotherapy during pregnancy for clinical stages IA-IIA Hodgkin’s disease Int J Radiat Oncol Biol Phys 1992;23(2):407-412 25 Antypas C, Sandilos P, Kouvaris J, et al Fetal dose evaluation during breast cancer radiotherapy Int J Radiat Oncol Biol Phys 1998;40(4):995-999 26 Ngu SL, Duval P, Collins C Foetal radiation dose in radiotherapy for breast cancer Australas Radiol 1992;36(4):321-322 27 Cardonick E, Iacobucci A Use of chemotherapy during human pregnancy Lancet Oncol 2004;5(5):283-291 28 Cardonick E, Usmani A, Ghaffar S Perinatal outcomes of a pregnancy complicated by cancer, including neonatal follow-up after in utero exposure to chemotherapy: results of an international registry Am J Clin Oncol 2010;33(3):221-228 29 Reynoso EE, Shepherd FA, Messner HA, Farquharson HA, Garvey MB, Baker MA Acute leukemia during pregnancy: the Toronto Leukemia Study Group experience with long-term follow-up of children exposed in utero to chemotherapeutic agents J Clin Oncol 1987;5(7):1098-1106 30 Wiebe VJ, Sipila PE Pharmacology of antineoplastic agents in pregnancy Crit Rev Oncol Hematol 1994;16(2):75-112 31 Van Calsteren K, Verbesselt R, Ottevanger N, et al Pharmacokinetics of chemotherapeutic agents in pregnancy: a preclinical and clinical study Acta Obstet Gynecol Scand 2010;89(10): 1338-1345 32 Caligiuri MA, Mayer RJ Pregnancy and leukemia Semin Oncol 1989;16(5):388-396 33 Briggs GG, Freeman RK, Yaffe SJ Drugs in Pregnancy and Lactation 7th ed Philadelphia, PA: Lippincott Williams & Wilkins; 2005 34 Ring AE, Smith IE, Jones A, Shannon C, Galani E, Ellis PA Chemotherapy for breast cancer during pregnancy: an 18-year experience from five London teaching hospitals J Clin Oncol 2005;23(18):4192-4197 35 Doll DC, Ringenberg QS, Yarbro JW Antineoplastic agents and pregnancy Semin Oncol 1989;16(5):337-346 36 Meddows M Pregnancy and the drug dilemma FDA Consumer magazine 2001 http://www.perinatology.com/Archive/FDA%20CAT.htm Accessed June 14, 2011 37 Zemlickis D, Lishner M, Erlich R, Koren G Teratogenicity and carcinogenicity in a twin exposed in utero to cyclophosphamide Teratog Carcinog Mutagen 1993;13(3):139-143 38 Ebert U, Loffler H, Kirch W Cytotoxic therapy and pregnancy Pharmacol Ther 1997;74(2):207-220 39 Germann N, Goffinet F, Goldwasser F Anthracyclines during pregnancy: embryo-fetal outcome in 160 patients Ann Oncol 2004;15(1):146-150 40 Aviles A, Neri N, Nambo MJ Long-term evaluation of cardiac function in children who received anthracyclines during pregnancy Ann Oncol 2006;17(2):286-288 41 Amant F, Van Calsteren K, Halaska MJ, et al Gynecologic cancers in pregnancy: guidelines of an international consensus meeting Int J Gynecol Cancer 2009;19(suppl 1):S1-S12 42 Mir O, Berveiller P, Ropert S, et al Emerging therapeutic options for breast cancer chemotherapy during pregnancy Ann Oncol 2008;19(4):607-613 43 Tabata T, Nishiura K, Tanida K, Kondo E, Okugawa T, Sagawa N Carboplatin chemotherapy in a pregnant patient with undifferentiated ovarian carcinoma: case report and review of the literature Int J Gynecol Cancer 2008;18(1):181-184 44 Han JY, Nava-Ocampo AA, Kim TJ, Shim JU, Park CT Pregnancy outcome after prenatal exposure to bleomycin, etoposide and cisplatin for malignant ovarian germ cell tumors: report of 2 cases Reprod Toxicol 2005;19(4): 557561 45 Giacalone PL, Laffargue F, Benos P, Rousseau O, Hedon B Cis-platinum neoadjuvant chemotherapy in a pregnant woman with invasive carcinoma of the uterine cervix Br J Obstet Gynaecol 1996;103(9):932-934 46 Karam A, Feldman N, Holschneider CH Neoadjuvant cisplatin and radical cesarean hysterectomy for cervical cancer in pregnancy Nat Clin Pract Oncol 2007;4(6):375-380 47 Mir O, Berveiller P, Ropert S, Goffinet F, Goldwasser F Use of platinum derivatives during pregnancy Cancer 2008;113(11): 3069-3074 48 Marnitz S, Kohler C, Oppelt P, et al Cisplatin application in pregnancy: first in vivo analysis of 7 patients Oncology 2010; 79(1-2): 72-77 49 Sood AK, Shahin MS, Sorosky JI Paclitaxel and platinum chemotherapy for ovarian carcinoma during pregnancy Gynecol Oncol 2001;83(3):599-600 50 Buller RE, Darrow V, Manetta A, Porto M, DiSaia PJ Conservative surgical management of dysgerminoma concomitant with pregnancy Obstet Gynecol 1992;79(5 Pt 2):887-890 51 Murray NA, Acolet D, Deane M, Price J, Roberts IA Fetal marrow suppression after maternal chemotherapy for leukaemia Arch Dis Child Fetal Neonatal Ed 1994;71(3):F209-210 52 Bennett CL, Silver SM, Djulbegovic B, et al Venous thromboembolism and mortality associated with recombinant erythropoietin and darbepoetin administration for the treatment of cancer-associated anemia JAMA 2008;299(8): 914-924 53 Marik PE Venous thromboembolism in pregnancy Clin Chest Med 2010;31(4):731-740 54 Calhoun DA, Rosa C, Christensen RD Transplacental passage of recombinant human granulocyte colony-stimulating factor in women with an imminent preterm delivery Am J Obstet Gynecol 1996;174(4):1306-1311 55 Dale DC, Cottle TE, Fier CJ, et al Severe chronic neutropenia: treatment and follow-up of patients in the Severe Chronic Neutropenia International Registry Am J Hematol 2003;72(2):82-93 56 Slone D, Siskind V, Heinonen OP, Monson RR, Kaufman DW, Shapiro S Antenatal exposure to the phenothiazines in relation to congenital malformations, perinatal mortality rate, birth weight, and intelligence quotient score Am J Obstet Gynecol 1977;128(5):486-488 57 Carmichael SL, Shaw GM Maternal corticosteroid use and risk of selected congenital anomalies Am J Med Genet 1999;86(3):242-244 58 Smallwood RA, Berlin RG, Castagnoli N, et al Safety of acid-suppressing drugs Dig Dis Sci 1995;40(suppl 2):S63-S80 59 Briggs GG, Freeman RK, Yaffe SJ Drugs in Pregnancy and Lactation 8th ed Philadelphia, PA: Lippincott Williams & Wilkins; 2008 60 Ofori B, Oraichi D, Blais L, Rey E, Berard A Risk of congenital anomalies in pregnant users of non-steroidal anti-inflammatory drugs: a nested casecontrol study Birth Defects Res B Dev Reprod Toxicol 2006;77(4):268-279 61 Zemlickis D, Lishner M, Degendorfer P, Panzarella T, Sutcliffe SB, Koren G Maternal and fetal outcome after invasive cervical cancer in pregnancy J Clin Oncol 1991;9(11):1956-1961 62 Baldauf JJ, Dreyfus M, Ritter J, Philippe E Colposcopy and directed biopsy reliability during pregnancy: a cohort study Eur J Obstet Gynecol Reprod Biol 1995;62(1):31-36 63 Paraiso MF, Brady K, Helmchen R, Roat TW Evaluation of the endocervical Cytobrush and Cervex-Brush in pregnant women Obstet Gynecol 1994;84(4):539-543 64 McCord ML, Stovall TG, Meric JL, Summitt RL Jr, Coleman SA Cervical cytology: a randomized comparison of four sampling methods Am J Obstet Gynecol 1992;166(6 Pt 1): 1772-1777; discussion 1777-1779 65 Averette HE, Nasser N, Yankow SL, Little WA Cervical conization in pregnancy Analysis of 180 operations Am J Obstet Gynecol 1970;106(4):543-549 66 Douvier S, Filipuzzi L, Sagot P [Management of cervical intra-epithelial neoplasm during pregnancy] Gynecol Obstet Fertil 2003;31(10):851-855 67 Hannigan EV, Whitehouse HH 3rd, Atkinson WD, Becker SN Cone biopsy during pregnancy Obstet Gynecol Oct 1982; 60(4):450-455 68 Goldberg GL, Altaras MM, Block B Cone cerclage in pregnancy Obstet Gynecol 1991;77(2):315-317 69 Fader AN, Alward EK, Niederhauser A, et al Cervical dysplasia in pregnancy: a multi-institutional evaluation Am J Obstet Gynecol 2010;203(2):113 e111-116 70 Yost NP, Santoso JT, McIntire DD, Iliya FA Postpartum regression rates of antepartum cervical intraepithelial neoplasia II and III lesions Obstet Gynecol 1999;93(3):359-362 71 Wright TC Jr, Massad LS, Dunton CJ, Spitzer M, Wilkinson EJ, Solomon D 2006 consensus guidelines for the management of women with abnormal cervical cancer screening tests Am J Obstet Gynecol 2007;197(4):346-355 72 Wright TC Jr, Massad LS, Dunton CJ, Spitzer M, Wilkinson EJ, Solomon D 2006 consensus guidelines for the management of women with cervical intraepithelial neoplasia or adenocarcinoma in situ Am J Obstet Gynecol 2007;197(4):340-345 73 Takushi M, Moromizato H, Sakumoto K, Kanazawa K Management of invasive carcinoma of the uterine cervix associated with pregnancy: outcome of intentional delay in treatment Gynecol Oncol 2002;87(2):185-189 74 Yahata T, Numata M, Kashima K, et al Conservative treatment of stage IA1 adenocarcinoma of the cervix during pregnancy Gynecol Oncol 2008;109(1):49-52 75 Roman LD, Felix JC, Muderspach LI, Agahjanian A, Qian D, Morrow CP Risk of residual invasive disease in women with microinvasive squamous cancer in a conization specimen Obstet Gynecol 1997;90(5):759-764 76 Giuntoli RL 2nd, Winburn KA, Silverman MB, Keeney GL, Cliby WA Frozen section evaluation of cervical cold knife cone specimens is accurate in the diagnosis of microinvasive squamous cell carcinoma Gynecol Oncol 2003;91(2):280-284 77 Nguyen C, Montz FJ, Bristow RE Management of stage I cervical cancer in pregnancy Obstet Gynecol Surv 2000;55(10): 633-643 78 Nucatola D, Roth N, Gatter M A randomized pilot study on the effectiveness and side-effect profiles of two doses of digoxin as fetocide when administered intraamniotically or intrafetally prior to second-trimester surgical abortion Contraception 2010;81(1):67-74 79 Sood AK, Sorosky JI, Krogman S, Anderson B, Benda J, Buller RE Surgical management of cervical cancer complicating pregnancy: a case-control study Gynecol Oncol 1996; 63(3):294-298 80 Monk BJ, Montz FJ Invasive cervical cancer complicating intrauterine pregnancy: treatment with radical hysterectomy Obstet Gynecol 1992;80(2):199-203 81 Lee RB, Neglia W, Park RC Cervical carcinoma in pregnancy Obstet Gynecol 1981;58(5):584-589 82 Sood AK, Sorosky JI, Mayr N, et al Radiotherapeutic management of cervical carcinoma that complicates pregnancy Cancer 1997;80(6):10731078 83 Benhaim Y, Haie-Meder C, Lhomme C, et al Chemoradiation therapy in pregnant patients treated for advanced-stage cervical carcinoma during the first trimester of pregnancy: report of two cases Int J Gynecol Cancer 2007;17(1):270-274 84 Creasman WT Cancer and pregnancy Ann N Y Acad Sci 2001;943:281-286 85 Creasman WT, Rutledge FN, Fletcher GH Carcinoma of the cervix associated with pregnancy Obstet Gynecol 1970; 36(4):495-501 86 Prem KA, Makowski EL, McKelvey JL Carcinoma of the cervix associated with pregnancy Am J Obstet Gynecol 1966;95(1): 99-108 87 Ostrom K, Ben-Arie A, Edwards C, Gregg A, Chiu JK, Kaplan AL Uterine evacuation with misoprostol during radiotherapy for cervical cancer in pregnancy Int J Gynecol Cancer 2003;13(3):340-343 88 Stoll BJ, Hansen NI, Bell EF, et al Neonatal outcomes of extremely preterm infants from the NICHD Neonatal Research Network Pediatrics 2010;126(3):443-456 89 Alouini S, Rida K, Mathevet P Cervical cancer complicating pregnancy: implications of laparoscopic lymphadenectomy Gynecol Oncol 2008;108(3):472-477 90 Favero G, Lanowska M, Schneider A, Marnitz S, Kohler C Laparoscopic pelvic lymphadenectomy in a patient with cervical cancer stage Ib1 complicated by a twin pregnancy J Minim Invasive Gynecol 2010;17(1):118120 91 Neoadjuvant chemotherapy for locally advanced cervical cancer: a systematic review and meta-analysis of individual patient data from 21 randomised trials Eur J Cancer 2003; 39(17):2470-2486 92 Sood AK, Sorosky JI, Mayr N, Anderson B, Buller RE, Niebyl J Cervical cancer diagnosed shortly after pregnancy: prognostic variables and delivery routes Obstet Gynecol 2000; 95(6 Pt 1):832-838 93 van der Vange N, Weverling GJ, Ketting BW, Ankum WM, Samlal R, Lammes FB The prognosis of cervical cancer associated with pregnancy: a matched cohort study Obstet Gynecol 1995;85(6):1022-1026 94 Baloglu A, Uysal D, Aslan N, Yigit S Advanced stage of cervical carcinoma undiagnosed during antenatal period in term pregnancy and concomitant metastasis on episiotomy scar during delivery: a case report and review of the literature Int J Gynecol Cancer 2007;17(5):1155-1159 95 Pettersson BF, Andersson S, Hellman K, Hellstrom AC Invasive carcinoma of the uterine cervix associated with pregnancy: 90 years of experience Cancer 2010;116(10):2343-2349 96 Condous G, Khalid A, Okaro E, Bourne T Should we be examining the ovaries in pregnancy? Prevalence and natural history of adnexal pathology detected at first-trimester sonography Ultrasound Obstet Gynecol 2004;24(1):62-66 97 Zanetta G, Mariani E, Lissoni A, et al A prospective study of the role of ultrasound in the management of adnexal masses in pregnancy BJOG 2003;110(6):578-583 98 Palmer J, Vatish M, Tidy J Epithelial ovarian cancer in pregnancy: a review of the literature BJOG 2009;116(4):480-491 99 Leiserowitz GS, Xing G, Cress R, Brahmbhatt B, Dalrymple JL, Smith LH Adnexal masses in pregnancy: how often are they malignant? Gynecol Oncol 2006;101(2):315-321 100 Leiserowitz GS Managing ovarian masses during pregnancy Obstet Gynecol Surv 2006;61(7):463-470 101 Yen CF, Lin SL, Murk W, et al Risk analysis of torsion and malignancy for adnexal masses during pregnancy Fertil Steril 2009;91(5):1895-1902 102 Lee GS, Hur SY, Shin JC, Kim SP, Kim SJ Elective vs conservative management of ovarian tumors in pregnancy Int J Gynaecol Obstet 2004;85(3):250-254 103 Giuntoli RL, 2nd, Vang RS, Bristow RE Evaluation and management of adnexal masses during pregnancy Clin Obstet Gynecol 2006;49(3):492-505 104 Mathevet P, Nessah K, Dargent D, Mellier G Laparoscopic management of adnexal masses in pregnancy: a case series Eur J Obstet Gynecol Reprod Biol 2003;108(2):217-222 105 Stepp KJ, Tulikangas PK, Goldberg JM, Attaran M, Falcone T Laparoscopy for adnexal masses in the second trimester of pregnancy J Am Assoc Gynecol Laparosc 2003;10(1):55-59 106 ICON2: randomised trial of single-agent carboplatin against three-drug combination of CAP (cyclophosphamide, doxorubicin, and cisplatin) in women with ovarian cancer ICON Collaborators International Collaborative Ovarian Neoplasm Study Lancet 1998;352(9140):1571-1576 107 Picone O, Lhomme C, Tournaire M, et al Preservation of pregnancy in a patient with a stage IIIB ovarian epithelial carcinoma diagnosed at 22 weeks of gestation and treated with initial chemotherapy: case report and literature review Gynecol Oncol 2004;94(2):600-604 108 Elit L, Bocking A, Kenyon C, Natale R An endodermal sinus tumor diagnosed in pregnancy: case report and review of the literature Gynecol Oncol 1999;72(1):123-127 109 Kwon YS, Mok JE, Lim KT, et al Ovarian cancer during pregnancy: clinical and pregnancy outcome J Korean Med Sci 2010;25(2):230-234 110 Beadle BM, Woodward WA, Middleton LP, et al The impact of pregnancy on breast cancer outcomes in women < or = 35 years Cancer 2009;115(6):1174-1184 111 Woo JC, Yu T, Hurd TC Breast cancer in pregnancy: a literature review Arch Surg 2003;138(1):91-98; discussion 99 112 Loibl S, von Minckwitz G, Gwyn K, et al Breast carcinoma during pregnancy International recommendations from an expert meeting Cancer 2006;106(2):237-246 113 Albrektsen G, Heuch I, Kvale G The short-term and long-term effect of a pregnancy on breast cancer risk: a prospective study of 802,457 parous Norwegian women Br J Cancer 1995;72(2):480-484 114 Wohlfahrt J, Andersen PK, Mouridsen HT, Melbye M Risk of late-stage breast cancer after a childbirth Am J Epidemiol 2001;153(11):1079-1084 115 Nettleton J, Long J, Kuban D, Wu R, Shaefffer J, El-Mahdi A Breast cancer during pregnancy: quantifying the risk of treatment delay Obstet Gynecol 1996;87(3):414-418 116 Litton JK, Theriault RL, Gonzalez-Angulo AM Breast cancer diagnosis during pregnancy Womens Health (Lond Engl) 2009;5(3):243-249 117 Yang WT, Dryden MJ, Gwyn K, Whitman GJ, Theriault R Imaging of breast cancer diagnosed and treated with chemotherapy during pregnancy Radiology 2006;239(1):52-60 118 Nicklas AH, Baker ME Imaging strategies in the pregnant cancer patient Semin Oncol 2000;27(6):623-632 119 Samuels TH, Liu FF, Yaffe M, Haider M Gestational breast cancer Can Assoc Radiol J 1998;49(3):172-180 120 Buchholz TA, Austin-Seymour MM, Moe RE, et al Effect of delay in radiation in the combined modality treatment of breast cancer Int J Radiat Oncol Biol Phys 1993;26(1):23-35 121 Lyman GH, Giuliano AE, Somerfield MR, et al American Society of Clinical Oncology guideline recommendations for sentinel lymph node biopsy in early-stage breast cancer J Clin Oncol 2005;23(30):7703-7720 122 Gentilini O, Cremonesi M, Toesca A, et al Sentinel lymph node biopsy in pregnant patients with breast cancer Eur J Nucl Med Mol Imaging 2010;37(1):78-83 123 Mondi MM, Cuenca RE, Ollila DW, Stewart JHt, Levine EA Sentinel lymph node biopsy during pregnancy: initial clinical experience Ann Surg Oncol 2007;14(1):218-221 124 Keleher A, Wendt R 3rd, Delpassand E, Stachowiak AM, Kuerer HM The safety of lymphatic mapping in pregnant breast cancer patients using Tc-99m sulfur colloid Breast J 2004;10(6):492-495 125 Amant F, Deckers S, Van Calsteren K, et al Breast cancer in pregnancy: recommendations of an international consensus meeting Eur J Cancer 2010;46(18):3158-3168 126 Hahn KM, Johnson PH, Gordon N, et al Treatment of pregnant breast cancer patients and outcomes of children exposed to chemotherapy in utero Cancer 2006;107(6):1219-1226 127 Giacalone PL, Laffargue F, Benos P Chemotherapy for breast carcinoma during pregnancy: a French national survey Cancer 1999;86(11):2266-2272 128 Azim HA Jr, Peccatori FA, Liptrott SJ, Catania C, Goldhirsch A Breast cancer and pregnancy: how safe is trastuzumab? Nat Rev Clin Oncol 2009;6(6):367-370 129 Kelly H, Graham M, Humes E, et al Delivery of a healthy baby after firsttrimester maternal exposure to lapatinib Clin Breast Cancer 2006;7(4):339341 130 Ibrahim EM, Ezzat AA, Baloush A, Hussain ZH, Mohammed GH Pregnancy-associated breast cancer: a case-control study in a young population with a high-fertility rate Med Oncol 2000;17(4):293-300 131 Halaska MJ, Pentheroudakis G, Strnad P, et al Presentation, management and outcome of 32 patients with pregnancy-associated breast cancer: a matched controlled study Breast J 2009;15(5):461-467 132 Ives A, Saunders C, Bulsara M, Semmens J Pregnancy after breast cancer: population based study BMJ 2007;334(7586):194 133 Velentgas P, Daling JR, Malone KE, et al Pregnancy after breast carcinoma: outcomes and influence on mortality Cancer 1999;85(11):24242432 134 Mueller BA, Simon MS, Deapen D, Kamineni A, Malone KE, Daling JR Childbearing and survival after breast carcinoma in young women Cancer 2003;98(6):1131-1140 135 Gelber S, Coates AS, Goldhirsch A, et al Effect of pregnancy on overall survival after the diagnosis of early-stage breast cancer J Clin Oncol 2001;19(6):1671-1675 136 Azim HA Jr, Santoro L, Pavlidis N, et al Safety of pregnancy following breast cancer diagnosis: a meta-analysis of 14 studies Eur J Cancer 2011;47(1):74-83 137 Alexander A, Samlowski WE, Grossman D, et al Metastatic melanoma in pregnancy: risk of transplacental metastases in the infant J Clin Oncol 2003;21(11):2179-2186 138 Gupta A, Driscoll MS Do hormones influence melanoma? Facts and controversies Clin Dermatol 2010;28(3):287-292 139 Balch CM, Gershenwald JE, Soong SJ, et al Final version of 2009 AJCC melanoma staging and classification J Clin Oncol 2009;27(36):6199-6206 140 Lens MB, Nathan P, Bataille V Excision margins for primary cutaneous melanoma: updated pooled analysis of randomized controlled trials Arch Surg 2007;142(9):885-891; discussion 891-883 141 Rousseau DL Jr, Ross MI, Johnson MM, et al Revised American Joint Committee on Cancer staging criteria accurately predict sentinel lymph node positivity in clinically node-negative melanoma patients Ann Surg Oncol 2003;10(5): 569-574 142 Chakera AH, Hesse B, Burak Z, et al EANM-EORTC general recommendations for sentinel node diagnostics in melanoma Eur J Nucl Med Mol Imaging 2009;36(10):1713-1742 143 Kirkwood JM, Strawderman MH, Ernstoff MS, Smith TJ, Borden EC, Blum RH Interferon alfa-2b adjuvant therapy of high-risk resected cutaneous melanoma: the Eastern Cooperative Oncology Group Trial EST 1684 J Clin Oncol 1996; 14(1):7-17 144 Kirkwood JM, Manola J, Ibrahim J, Sondak V, Ernstoff MS, Rao U A pooled analysis of eastern cooperative oncology group and intergroup trials of adjuvant high-dose interferon for melanoma Clin Cancer Res 2004;10(5):1670-1677 145 Eggermont AM, Suciu S, Santinami M, et al Adjuvant therapy with pegylated interferon alfa-2b versus observation alone in resected stage III melanoma: final results of EORTC 18991, a randomised phase III trial Lancet 2008;372(9633):117-126 146 Eggermont AM, Suciu S, MacKie R, et al Post-surgery adjuvant therapy with intermediate doses of interferon alfa 2b versus observation in patients with stage IIb/III melanoma (EORTC 18952): randomised controlled trial Lancet 2005; 366(9492):1189-1196 147 Hauschild A, Weichenthal M, Rass K, et al Efficacy of low-dose interferon {alpha}2a 18 versus 60 months of treatment in patients with primary melanoma of >= 1.5 mm tumor thickness: results of a randomized phase III DeCOG trial J Clin Oncol 2010;28(5):841-846 148 Egberts F, Lischner S, Russo P, Kampen WU, Hauschild A Diagnostic and therapeutic procedures for management of melanoma during pregnancy: risks for the fetus? J Dtsch Dermatol Ges 2006;4(9):717-720 149 Hiratsuka M, Minakami H, Koshizuka S, Sato I Administration of interferon-alpha during pregnancy: effects on fetus J Perinat Med 2000;28(5):372-376 150 Shuff JH, Siker ML, Daly MD, Schultz CJ Role of radiation therapy in cutaneous melanoma Clin Plast Surg 2010; 37(1):147-160 151 Lee SM, Betticher DC, Thatcher N Melanoma: chemotherapy Br Med Bull 1995;51(3):609-630 152 Middleton MR, Grob JJ, Aaronson N, et al Randomized phase III study of temozolomide versus dacarbazine in the treatment of patients with advanced metastatic malignant melanoma J Clin Oncol 2000;18(1):158-166 153 O’Meara AT, Cress R, Xing G, Danielsen B, Smith LH Malignant melanoma in pregnancy A population-based evaluation Cancer 2005;103(6):1217-1226 154 Lens MB, Rosdahl I, Ahlbom A, et al Effect of pregnancy on survival in women with cutaneous malignant melanoma J Clin Oncol 2004;22(21):43694375 155 Reintgen DS, McCarty KS Jr, Vollmer R, Cox E, Seigler HF Malignant melanoma and pregnancy Cancer 1985;55(6): 1340-1344 156 Cooper DS, Doherty GM, Haugen BR, et al Revised American Thyroid Association management guidelines for patients with thyroid nodules and differentiated thyroid cancer Thyroid 2009;19(11):1167-1214 157 Mack WJ, Preston-Martin S, Bernstein L, Qian D, Xiang M Reproductive and hormonal risk factors for thyroid cancer in Los Angeles County females Cancer Epidemiol Biomarkers Prev 1999;8(11):991-997 158 Mazzaferri EL Management of a solitary thyroid nodule N Engl J Med 1993;328(8):553-559 159 Morris PC Thyroid cancer complicating pregnancy Obstet Gynecol Clin North Am 1998;25(2):401-405 160 Moosa M, Mazzaferri EL Outcome of differentiated thyroid cancer diagnosed in pregnant women J Clin Endocrinol Metab 1997;82(9):28622866 161 Wu M A comparative study of 200 head and neck FNAs performed by a cytopathologist with versus without ultrasound guidance: evidence for improved diagnostic value with ultrasound guidance Diagn Cytopathol 2011;39(10):743-751 162 Owen RP, Chou KJ, Silver CE, et al Thyroid and parathyroid surgery in pregnancy Eur Arch Otorhinolaryngol 2010;267(12): 1825-1835 163 Mazzaferri EL, Jhiang SM Long-term impact of initial surgical and medical therapy on papillary and follicular thyroid cancer Am J Med 1994;97(5):418-428 164 McGriff NJ, Csako G, Gourgiotis L, Lori CG, Pucino F, Sarlis NJ Effects of thyroid hormone suppression therapy on adverse clinical outcomes in thyroid cancer Ann Med 2002;34(7-8): 554-564 165 LeBeau SO, Mandel SJ Thyroid disorders during pregnancy Endocrinol Metab Clin North Am 2006;35(1):117-136, vii 166 Rosen IB, Korman M, Walfish PG Thyroid nodular disease in pregnancy: current diagnosis and management Clin Obstet Gynecol 1997;40(1):81-89 167 Doherty CM, Shindo ML, Rice DH, Montero M, Mestman JH Management of thyroid nodules during pregnancy Laryngoscope 1995;105(3 Pt 1):251-255 168 Herzon FS, Morris DM, Segal MN, Rauch G, Parnell T Coexistent thyroid cancer and pregnancy Arch Otolaryngol Head Neck Surg 1994;120(11):11911193 169 Yasmeen S, Cress R, Romano PS, et al Thyroid cancer in pregnancy Int J Gynaecol Obstet 2005;91(1):15-20 170 Vannucchi G, Perrino M, Rossi S, et al Clinical and molecular features of differentiated thyroid cancer diagnosed during pregnancy Eur J Endocrinol 2010;162(1):145-151 171 Hirsch D, Levy S, Tsvetov G, et al Impact of pregnancy on outcome and prognosis of survivors of papillary thyroid cancer Thyroid 2010;20(10):11791185 172 Leboeuf R, Emerick LE, Martorella AJ, Tuttle RM Impact of pregnancy on serum thyroglobulin and detection of recurrent disease shortly after delivery in thyroid cancer survivors Thyroid 2007;17(6):543-547 173 Hurley TJ, McKinnell JV, Irani MS Hematologic malignancies in pregnancy Obstet Gynecol Clin North Am 2005;32(4): 595-614 174 Weisz B, Schiff E, Lishner M Cancer in pregnancy: maternal and fetal implications Hum Reprod Update 2001;7(4):384-393 175 Gelb AB, van de Rijn M, Warnke RA, Kamel OW Pregnancy-associated lymphomas A clinicopathologic study Cancer 1996;78(2):304-310 176 Shapira T, Pereg D, Lishner M How I treat acute and chronic leukemia in pregnancy Blood Rev 2008;22(5):247-259 177 Vassilakopoulos TP, Angelopoulou MK, Siakantaris MP, et al Combination chemotherapy plus low-dose involved-field radiotherapy for early clinical stage Hodgkin’s lymphoma Int J Radiat Oncol Biol Phys 2004;59(3):765781 178 Rizack T, Mega A, Legare R, Castillo J Management of hematological malignancies during pregnancy Am J Hematol 2009;84(12):830-841 179 Connors JM Challenging problems: coincident pregnancy, HIV infection, and older age Hematology Am Soc Hematol Educ Program 2008:334-339 180 Pereg D, Koren G, Lishner M The treatment of Hodgkin’s and nonHodgkin’s lymphoma in pregnancy Haematologica 2007;92(9):1230-1237 181 Aviles A, Diaz-Maqueo JC, Talavera A, Guzman R, Garcia EL Growth and development of children of mothers treated with chemotherapy during pregnancy: current status of 43 children Am J Hematol 1991;36(4):243-248 182 Greenlund LJ, Letendre L, Tefferi A Acute leukemia during pregnancy: a single institutional experience with 17 cases Leuk Lymphoma 2001;41(56):571-577 183 Wagner VM, Hill JS, Weaver D, Baehner RL Congenital abnormalities in baby born to cytarabine treated mother Lancet 1980;2(8185):98-99 184 Walker JW, Reinisch JF, Monforte HL Maternal pulmonary adenocarcinoma metastatic to the fetus: first recorded case report and literature review Pediatr Pathol Mol Med 2002;21(1):57-69 185 Lishner M, Zemlickis D, Degendorfer P, Panzarella T, Sutcliffe SB, Koren G Maternal and foetal outcome following Hodgkin’s disease in pregnancy Br J Cancer 1992;65(1): 114-117 186 Langagergaard V, Horvath-Puho E, Norgaard M, Norgard B, Sorensen HT Hodgkin’s disease and birth outcome: a Danish nationwide cohort study Br J Cancer 2008;98(1):183-188 187 Bennett JM, Young ML, Andersen JW, et al Long-term survival in acute myeloid leukemia: the Eastern Cooperative Oncology Group experience Cancer 1997;80(suppl 11):2205-2209 188 Catanzarite VA, Ferguson JE 2nd Acute leukemia and pregnancy: a review of management and outcome, 1972-1982 Obstet Gynecol Surv 1984;39(11):663-678 189 Boutselis JG Intraepithelial carcinoma of the cervix associated with pregnancy Obstet Gynecol 1972;40(5):657-666 190 Dudan RC, Yon JL, Ford JH, Averette HE Carcinoma of the cervix and pregnancy Gynecol Oncol 1973;1:283 191 Thompson JD, Caputo TA, Franklin EW, 3rd, Dale E The surgical management of invasive cancer of the cervix in pregnancy Am J Obstet Gynecol 1975;121(6):853-B63 192 Nisker JA, Shubat M Stage IB cervical carcinoma and pregnancy: report of 49 cases Am J Obstet Gynecol 1983; 145(2):203-206 193 Greer BE, Easterling TR, McLennan DA, et al Fetal and maternal considerations in the management of stage I-B cervical cancer during pregnancy Gynecol Oncol 1989;34(1):61-65 194 Duggan B, Muderspach LI, Roman LD, Curtin JP, d’Ablaing G, 3rd, Morrow CP Cervical cancer in pregnancy: reporting on planned delay in therapy Obstet Gynecol 1993;82(4 Pt 1): 598-602 195 Sorosky JI, Squatrito R, Ndubisi BU, et al Stage I squamous cell cervical carcinoma in pregnancy: planned delay in therapy awaiting fetal maturity Gynecol Oncol 1995;59(2):207-210 196 Sorosky J Stage 1b cervical carcinoma in pregnancy: awaiting fetal maturity J Gynecol Tech 1996;2:155-158 197 van Vliet W, van Loon AJ, ten Hoor KA, Boonstra H Cervical carcinoma during pregnancy: outcome of planned delay in treatment Eur J Obstet Gynecol Reprod Biol 1998;79(2): 153-157 198 Traen K, Svane D, Kryger-Baggesen N, Bertelsen K, Mogensen O Stage Ib cervical cancer during pregnancy: planned delay in treatment–case report Eur J Gynaecol Oncol 2006;27(6): 615-617 199 Germann N, Haie-Meder C, Morice P, et al Management and clinical outcomes of pregnant patients with invasive cervical cancer Ann Oncol 2005;16(3):397-402 200 Lee JM, Lee KB, Kim YT, et al Cervical cancer associated with pregnancy: results of a multicenter retrospective Korean study (KGOG-1006) Am J Obstet Gynecol 2008;198(1): 92 e91-96 201 Gonzalez Bosquet E, Castillo A, Medina M, Sunol M, Capdevila A, Lailla JM Stage 1B cervical cancer in a pregnant woman at 25 weeks of gestation Eur J Gynaecol Oncol 2008;29(3):276-279 202 Ishioka S, Ezaka Y, Endo T, et al Outcomes of planned delivery delay in pregnant patients with invasive gynecologic cancer Int J Clin Oncol 2009;14(4):321-325 203 Favero G, Chiantera V, Oleszczuk A, et al Invasive cervical cancer during pregnancy:laparoscopic nodal evaluation before oncologic treatment delay Gynecol Oncol 2010;118(2): 123-127 204 Lai CH, Hsueh S, Chang TC, et al Prognostic factors in patients with bulky stage IB or IIA cervical carcinoma undergoing neoadjuvant chemotherapy and radical hysterectomy Gynecol Oncol 1997;64(3):456-462 205 Tewari K, Cappuccini F, Gambino A, Kohler MF, Pecorelli S, DiSaia PJ Neoadjuvant chemotherapy in the treatment of locally advanced cervical carcinoma in pregnancy: a report of two cases and review of issues specific to the management of cervical carcinoma in pregnancy including planned delay of therapy Cancer 1998;82(8):1529-1534 206 Marana HR, de Andrade JM, da Silva Mathes AC, Duarte G, da Cunha SP, Bighetti S Chemotherapy in the treatment of locally advanced cervical cancer and pregnancy Gynecol Oncol 2001;80(2):272-274 207 Caluwaerts S, K VANC, Mertens L, et al Neoadjuvant chemotherapy followed by radical hysterectomy for invasive cervical cancer diagnosed during pregnancy: report of a case and review of the literature Int J Gynecol Cancer 2006;16(2): 905-908 208 Benhaim Y, Pautier P, Bensaid C, Lhomme C, Haie-Meder C, Morice P Neoadjuvant chemotherapy for advanced stage cervical cancer in a pregnant patient: report of one case with rapid tumor progression Eur J Obstet Gynecol Reprod Biol 2008;136(2):267-268 209 Bader AA, Petru E, Winter R Long-term follow-up after neoadjuvant chemotherapy for high-risk cervical cancer during pregnancy Gynecol Oncol 2007;105(1):269-272 210 Palaia I, Pernice M, Graziano M, Bellati F, Panici PB Neoadjuvant chemotherapy plus radical surgery in locally advanced cervical cancer during pregnancy: a case report Am J Obstet Gynecol 2007;197(4):e5-6 211 Seamon LG, Downey GO, Harrison CR, Doss B, Carlson JW Neoadjuvant chemotherapy followed by post-partum chemoradiotherapy and chemoconsolidation for stage IIIB glassy cell cervical carcinoma during pregnancy Gynecol Oncol 2009;114(3):540-541 212 Rabaiotti E, Sigismondi C, Montoli S, Mangili G, Candiani M, Vigano R Management of locally advanced cervical cancer in pregnancy: a case report Tumori 2010;96(4):623-626 ... Surgery and Robotics Section of Gynecologic Oncology Department of Obstetrics and Gynecology Cleveland Clinic Cleveland, Ohio Chapter 31 Jeffrey M Fowler, MD John G Boutselis Professor in Gynecologic Oncology Department of Obstetrics... Lowery, MD Gynecologic Oncology Fellow Division of Gynecologic Oncology Duke University Medical Center Durham, North Carolina Chapter 10 Karen H Lu, MD Professor Department of Gynecologic Oncology and Reproductive Medicine University of... Integrative Oncology, Quality of Life, and Supportive Care Diljeet K Singh and Vivian E von Gruenigen 23 Surgical Instrumentation and Sutures John C Elkas and Addie Alkhas IV SURGICAL ATLAS 24 Ovarian and Fallopian Tube Procedures