Combinatorial synthesis of natural product based libraries

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Combinatorial synthesis of natural product based libraries

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... 2006 1:19 PM Combinatorial Synthesis of Natural Product- Based Libraries TABLE 1.1 Dictionary of Natural Products Classification of Natural Products Classification Representative Natural Product Aliphatics... PM Combinatorial Synthesis of Natural Product- Based Libraries TABLE 1.1 (CONTINUED) Dictionary of Natural Products Classification of Natural Products Classification Representative Natural Product. .. overview of the fields of natural products research and combinatorial chemistry The latter half of the chapter examines several areas of research in the synthesis of natural- product- based libraries

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Mục lục

  • 9340_fm

    • Combinatorial Synthesis of Natural Product-Based Libraries

      • Preface

      • Acknowledgments

      • Editor

      • Contributors

      • Table of Contents

      • 9340_ch01

        • Combinatorial Synthesis of Natural Product-Based Libraries

          • Table of Contents

            • Chapter 1: Chemistry on the Interface of Natural Products and Combinatorial Chemistry

              • 1.1 NATURAL PRODUCTS: A RICH SOURCE OF DRUG DISCOVERY LEADS

              • 1.2 NATURAL PRODUCT-BASED COMBINATORIAL SYNTHESIS FOR LEAD DISCOVERY

              • 1.3 SOLID-PHASE SYNTHESIS OF PROSTAGLANDINS AND VANCOMYCIN

              • 1.4 BENZOPYRANS: A PRIVILEGED PLATFORM FOR DRUG DISCOVERY

              • 1.5 DIVERSITY-ORIENTED SYNTHESIS FOR CHEMICAL BIOLOGY

              • 1.6 PROTEIN STRUCTURE SIMILARITY CLUSTERING FOR LIBRARY DESIGN

              • 1.7 SMALL-MOLECULE LIBRARIES DERIVED FROM QUININE AND L-HYDROXYPROLINE

              • 1.8 THE FUTURE OF NATURAL PRODUCT-BASED COMBINATORIAL LIBRARIES

              • REFERENCES

              • 9340_ch02

                • Combinatorial Synthesis of Natural Product-Based Libraries

                  • Table of Contents

                    • Chapter 2: Natural Products and Combinatorial Chemistry — An Uneasy Past but a Glorious Future

                      • 2.1 INTRODUCTION

                      • 2.2 A BRIEF HISTORY OF NATURAL PRODUCTS AND DRUG DISCOVERY

                        • 2.2.1 PRIOR TO THE 19TH CENTURY

                        • 2.2.2 1900–1940

                        • 2.2.3 1940–1970

                        • 2.2.4 1970–1990

                        • 2.2.5 1990–2000

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