Image 060_57 Herpes Simplex This is a close-up of a herpes simplex lesion of the lower lip on the 2nd day after onset Also known as a cold sore, this lesion is caused by the contagious herpes simplex virus Type-1 (HSV-1), and should not be confused with a canker sore, which is not contagious The HSV-1 virus remains in the body throughout an exposed person’s entire life Red Book Online Visual Library, 2006 Image 060_57 Available at: http://aapredbook.aappublications.org/visual Accessed November 29, 2007 Copyright ©2006 American Academy of Pediatrics