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IMMUNOSUPPRESSION
– ROLE IN HEALTH AND
DISEASES
Edited by Suman Kapur
and Maristela Barbosa Portela
Immunosuppression – Role in Health and Diseases
Edited by Suman Kapur and Maristela Barbosa Portela
Published by InTech
Janeza Trdine 9, 51000 Rijeka, Croatia
Copyright © 2012 InTech
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Publishing Process Manager Ivana Zec
Technical Editor Teodora Smiljanic
Cover Designer InTech Design Team
First published February, 2012
Printed in Croatia
A free online edition of this book is available at www.intechopen.com
Additional hard copies can be obtained from orders@intechweb.org
Immunosuppression – Role in Health and Diseases, Edited by Suman Kapur and
Maristela Barbosa Portela
p. cm.
ISBN 978-953-51-0152-9
Contents
Preface IX
Part 1 Suppression and Regulation 1
Chapter 1 Role of Opioidergic System in
Humoral Immune Response 3
Suman Kapur, Anuradha Pal and Shashwat Sharad
Chapter 2 Endotoxin Tolerance as a Key Mechanism for
Immunosuppression 21
Subhra K. Biswas and Irina N. Shalova
Chapter 3 Spleen Tyrosine Kinase:
A Novel Target in Autoimmunity 41
Stephen P. McAdoo and Frederick W. K. Tam
Chapter 4 Genetic Variation in AhR Gene
Related to Dioxin Sensitivity in the Japanese Field Mouse,
Apodemus speciosus 57
Hiroko Ishiniwa, Kazuhiro Sogawa, Ken-ichi Yasumoto,
Nobuhiko Hoshi, Toshifumi Yokoyama,
Ken Tasaka and Tsuneo Sekijima
Chapter 5 Anti-RhD-Mediated Immunosuppression: Can Monoclonal
Antibodies Imitate the Action of Polyclonal Antibodies? 77
Natalia Olovnikova
Chapter 6 Immunotropic Properties of GABA-ergic Agents
in Suppression 107
N. Tyurenkov and M. A. Samotrueva
Chapter 7 Immunodepression and Immunosuppression
During Aging 125
Véronique Thomas-Vaslin, Adrien Six, Hang-Phuong Pham,
Cira Dansokho, Wahiba Chaara, Bruno Gouritin,
Bertrand Bellier and David Klatzmann
VI Contents
Chapter 8 Chronic Immune Response Hypothesis
for Chronic Fatigue Syndrome:
Experimental Results and Literature Overview 147
E. V. Svirshchevskaya
Chapter 9 T Cell Suppression in Burn and Septic Injuries 161
Nadeem Fazal
Chapter 10 Immunosuppression in Helminth Infection 191
Maria Doligalska and Katarzyna Donskow-Łysoniewska
Chapter 11 Microbial Immunosuppression 215
Mohamed G. Elfaki, Abdullah A. Al-Hokail
and Abdelmageed M. Kambal
Chapter 12 Measles Virus Infection:
Mechanisms of Immune Suppression 225
Xuelian Yu and Reena Ghildyal
Chapter 13 Immunoregulation:
A Proposal for an Experimental Model 255
Marcela Šperanda and Ivica Valpotić
Part 2 Transplantation and Novel Therapies 291
Chapter 14 Cellular Therapies for Immunosuppression 293
Nathalie Cools, Viggo F. I. Van Tendeloo and Zwi N. Berneman
Chapter 15 Low Immunogenic Potential
of Human Neural Stem Cells 317
L. De Filippis, L. Rota Nodari and Maurizio Gelati
Chapter 16 Current Immunosuppression
in Abdominal Organ Transplantation 335
Raffaele Girlanda, Cal S. Matsumoto, Keith J. Melancon
and Thomas M. Fishbein
Chapter 17 Induction Therapy in Renal Transplant Recipients 357
Cheguevara Afaneh, Meredith J. Aull,
Sandip Kapur and David B. Leeser
Chapter 18 Radiotherapy and Immunity – A Mini Review 385
Rosangela Correa Villar
Chapter 19 The Role of Cyclosporine A in the Treatment
of Prosthetic Vascular Graft Infections with
the Use of Arterial Homografts 407
Artur Pupka and Tomasz Płonek
Contents VII
Chapter 20 Clinical Immunosuppression in Solid Organ
and Composite Tissue Allotransplantation 423
Barbara Kern and Robert Sucher
Chapter 21 HIV/AIDS Associated Malignant Disorders:
Role of Highly Active Antiretroviral Therapy 433
Angel Mayor, Yelitza Ruiz, Diana Fernández
and Robert Hunter-Mellado
Chapter 22 E-Health 2.0 Developments in Treatment and Research in
Multiple Sclerosis 457
Peter Joseph Jongen
“Dedicated to my parents, students
and most of all my mentor and guide Prof. G. P Talwar”
. IMMUNOSUPPRESSION – ROLE IN HEALTH AND DISEASES Edited by Suman Kapur and Maristela Barbosa Portela Immunosuppression – Role in Health and Diseases Edited by Suman. hard copies can be obtained from orders@intechweb.org Immunosuppression – Role in Health and Diseases, Edited by Suman Kapur and Maristela Barbosa Portela p. cm. ISBN 978-953-51-0152-9. mechanism by which the body recognizes and defends itself against foreign or non-self Immunosuppression – Role in Health and Diseases 4 substances and organisms such as bacteria, viruses, and
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