[...]... preclinical medicine or other health-related courses One of the challenges in studying physiology and pharmacology is the very large number of facts and ideas that must be remembered; this factual load can seem daunting To understand how drugs produce their therapeutic effect, it is essential to have knowledge and understanding of both the physiological mechanisms which underpin pharmacology and the. .. disorder and the associated symptoms; • describe its pathophysiology; • explain the pharmacological approaches to managing the symptoms of this condition Finally, after checking the luggage several times, Jane and her husband managed to get out of the house in time to go to the airport for their holiday abroad On their way to the airport, Jane asked her husband if they could go back and check the front... underlying pathophysiology; • understand and describe the pharmacology of agents currently used in the treatment of the disorder studied; • appreciate some of the key issues in determining appropriate medication; • continue to develop your problem-solving skills Using This Book Clinical Physiology and Pharmacology is written primarily for undergraduate students studying modules in physiology and pharmacology. .. Index 319 337 Preface Introduction Physiology plays a major role in the scientific foundation of medicine and other subjects related to human health and physical performance Pharmacology is the science which deals with the effects of drugs on living systems and their use in the treatment of disease This book is designed to enhance students’ understanding of physiology and pharmacology via a series of case... these cases and would be happy to receive your comments on this book to inform future editions xii PREFACE Aims of the Book The case studies and the questions which follow will aid your understanding of many types of biological and clinical factors They are intended to help you prepare for problems associated with clinical physiology and pharmacology that you may meet both in formal examinations and. .. Q2 What are the symptoms of mania? Q3 Outline the underlying pathophysiology of mania Q4 Is there a relationship between the development of mania and the use of antidepressants? Q5 When lithium therapy is initiated, what is the recommended daily dose? Q6 Describe the mechanism of action of lithium Q7 Comment on the side effects associated with the use of lithium CASE STUDY 2 A DANGEROUS FATHER? 7 Q8... states: these range from depression to periods when he becomes agitated, extremely talkative and does not want to go to sleep His mood then appears elevated and euphoric and these irritable moods can last for weeks On further questioning by the doctor, it became clear that her paternal grandfather had also suffered similar mood swings Q1 What is the likely diagnosis for Mr Watson? Q2 Comment on the pathophysiology... STUDY 1 A mother’s loss Learning outcomes On completion of the following case study, you will be able to: • describe the signs and symptoms associated with this disorder; • describe the underlying pathophysiology of the disorder presented; • outline pharmacological approaches to the management of the symptoms; • explain how drugs may cause their clinical benefits and side effects; • outline the mechanism... about the case study Key points are provided for each case and are intended both as a short summary of the essential points and as a focus for revision They can be used to preview or review the case content Important points should then be easier to remember in the future, especially when, by association, you can recall them in an appropriate clinical context The glossary collects simple definitions of the. .. this and decided that John should see the family doctor A diagnosis was made and the drug, methylphenidate, was prescribed Q1 What is the likely diagnosis of John’s disruptive behaviour? Q2 What is ADHD? Comment on the subtypes of ADHD and its symptoms Q3 Comment on the pathophysiology of ADHD Q4 What is the difference between ADHD and ADD? Q5 To which category of drugs does methylphenidate belong and . to: • understand and describe the signs and symptoms of the disorder in question and its underlying pathophysiology; • understand and describe the pharmacology. PREFACE Aims of the Book The case studies and the questions which follow will aid your understanding of many types of biological and clinical factors. They are