Báo cáo y học: "Inhalation with Fucose and Galactose for Treatment of

Báo cáo y học: "Inhalation with Fucose and Galactose for Treatment of Pseudomonas Aeruginosa in Cystic Fibrosis Patients"

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Báo cáo Y học: Puriﬁcation, characterization and subunits identiﬁcation of the diol dehydratase of Lactobacillus collinoides pot

... The enzymerequired the adenosylcobalamin coenzyme for catalyticactivity and the Km for the cofactor was 8 lM. Inactivation of the enzyme was observed by both glycerol and cyano-cobalamin. ... activity was deﬁned as 1 lmol of aldehydeformed per minute. For the assays, between 0.001 and 0.01units of enzyme were used. Protein concentration wasdetermined by the method of Lowry [22] with ... 2, 4 and 6 min with 1volume of 1Mcitrate buffer (pH 3.6) and the 3-hydroxy-propionaldehyde was monitored using the 3-methyl-2-benzothiazolinone hydrazone method. One unit of dioldehydratase...

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Tài liệu Báo cáo khoa học: Angiopoietin-like proteins: emerging targets for treatment of obesity and related metabolic diseases pptx

... weightgain, in ammation induces a state of ‘leptin resistance’ in obese animals and humans resulting in development of hyperleptinemia. Similarly, hyperleptinemia is aconsequence of the development ... diet-induced obesity and insulin resis-tance [14]. Taken together, these ﬁndings suggest thatANGPTL6 ⁄ AGF in the circulation counteracts obesity and related insulin resistance by increasing systemicenergy ... upregulated in obesity(particularly visceral obesity) and correlated with thelevels of systemic insulin resistance and in ammation[15]. Circulating ANGPTL2 levels decrease with bodyweight reduction,...

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Báo cáo Y học: DAP kinase activity is critical for C2-ceramide-induced apoptosis in PC12 cells ppt

... overexpression of wild-type DAP kinaseenhanced the sensitivity to C2-andC8-ceramide, while acatalytically inactive DAP kinase mutant and a constructcontaining the death domain and C-terminal tail of ... mutant lacking the c almodulin-bindingdomain, is constitutively active, while mutant K42A-DK, in which a lysine residue within the kinase domain isreplaced by an alanine residue, is inactive. ... not cytotoxic [4]. In addition, DAP kinase contains unique domains and motifs, including eight ankyrin repeats, two potential ATP/GTP binding sites (P-loops), a cytoskeleton bindingdomain, a...