... reserved Research Paper Transcriptome analysis of murine thymocytes reveals age-associated changes in thymic gene expression Ana Lustig1, Arnell Carter1, Dorothy Bertak1, Divya Enika1, Bolormaa Vandanmagsar1, ... significantly change with thymocyte age. Interesting, the expression of several immunoglobulin chains were also found to be significantly increased in aged...
... amounts of sialylated Hex3 glycoforms were indicated.
b
Minor amounts of Hex2 and Hex3 glycoforms lacking acetyl groups or
containing a second glycyl group were indicated.
c
Very minor amounts of ... nd
wild-type strains of H. in uenzae by us and others [10–19]
have resulted in a structural model consisting of a conserved
triheptosyl inner-core moiety (labelled HepI–HepIII) in...
... represents the general trend of protein changes for the experimental sample to control detected by using the Odyssey Infrared Imaging System. (+) means an increase of signal intensity, and (-) means ... represents the general trend of protein changes for the experimental sample to control detected by using the Odyssey Infrared Imaging System. (+) means an increase of signal intens...
... the pathogenesis of AML. During sequence analysis of exon 10 in the AML samples we identified a new intronic SNP which we subsequently confirmed by sequencing DNA samples of 51 healthy individuals. ... healthy individuals. Interestingly, this SNP had not yet been registered in any SNP databases despite of its high frequency of 20% in samples of patients with AML and 13,7%...
... residues phenylalanine and tyrosine typical of the Ig-fold are bold in each domain.
Fig. 5. Inhibition of in vivo myotoxicity of myotoxins I or II by DM64.
Groups of four mice were injected intramuscularly ... first three
domains and are present in the inhibitory receptors of
Fig. 6. Inhibition of in vitro cytotoxicity of myotoxins I or II by DM64.
Cytotoxicity was analyz...
... Mchaourab, H.S. (1999) Folding pattern of the
a-crystallin domain in aA-crystallin determined by site-directed
spin labelling. J. Mol. B iol. 294, 561–577.
68. To
¨
ro
¨
k, Z., Goloubinoff, P., Horva
´
th, ... [66], and disassembly of active units
from an oligomeric (storage) state of a-crystallin was
proposed, upon structural analysis of aA-crystallin by site-
directed spin labell...
... indicating
either a direct interaction with the triad amino acids or a
consequence of steric hindrance causing an interference in
enzymatic activity.
In conclusion, by analyzing individual phage antibodies
isolated ... proteins in
rye, barley and possibly oats [1], with gliadins, specific
antigenic determinants found in glutens [2], playing a
prominent role. The disease is characteri...
... 2-N-(3-O-
acyl
4
-acyl
2
)-b-GlcN-(1–6)-2-N-acyl
1
)3-O-acyl
3
-GlcN where
acyl
1
,acyl
2
and acyl
3
are 3-hydroxyhexadecanoic or 3-hy-
droxyoctadecanoic acids, acyl
4
is tetradecanoic or (minor)
hexadecanoic ... C-1, and was
mostly present in an a-pyranose form. Acyl
1
,acyl
2
and acyl
3
residues had hydroxy or acyloxy groups at C-3 (
13
C signals
of C-3 at 69.0–72.4 p.p.m.), while acyl...
... core-oligosaccha-
rides of E. coli F653 LPS for which only preliminary data
were available and investigated the deacylated LPS by
NMR and MS. The proposed structure determined pre-
viously by methylation analysis ... Verhoef, J. & Sinnwell, V. (1988) Iolation and chemical
analysis of 7-O-(2-amino-2-deoxy-a-
D
-glucopyranosyl-
L
-glycero-
D
-manno-heptose as a constituent of the...
... Kinetic analysis of hydroxylation of saturated fatty acids
by recombinant P450foxy produced by an
Escherichia coli
expression
system
7
Tatsuya
7
Kitazume
1
, Akinori Tanaka
1
, Naoki Takaya
1
, ... substrate-accessing channel, and their
guanidinium and hydroxyl groups, respectively, play crucial
roles in the binding of the substrate by interacting with the
carboxyl group of the su...