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Báo cáo y học: "HLA-DR regulation and the influence of GM-CSF on transcription, surface expression and shedding

Báo cáo y học:

Báo cáo y học: "Special considerations in the treatment of patients with bipolar disorder and medical co-morbidities"

... diagnosis of general medical conditions may bedelayed. As the physician with the most (and often theonly) contact with these patients, psychiatrists need to bevigilant in detecting early signs and symptoms ... must be aware of the effects of psychotropicson the kidneys, as well the effects of decreased renal func-tioning on the pharmacokinetics of medicationsprescribed .Of all the medications used to ... Greene T, Eknoyan G, Levey AS: Prevalence ofchronic kidney disease and decreased kidney function in theadult US population: third national health and nutritionexamination survey. Am J Kidney Dis 2003,...
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Báo cáo y học:

Báo cáo y học: "Clinical Strategy for the Management of Solid Pseudopapillary Tumor of the Pancreas: Aggressive or Less"

... located in the portion of body or tail of the pancreas. For tumors of SPT located in the neck and body of the pancreas, resection of the mid-portion of the pancreas and the mass with preserving the ... Shandong University, Jinan Shandong, China; 2. Department of Rehabilitation, Shandong Provincial Hospital affiliated to Shandong University, Jinan Shandong, China.  Corresponding author: Hong ... solid and cystic components and displace-ment of nearby structures.15,17 Additionally, CT can play much more important role by providing further information about the size, location, the...
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Tài liệu Báo cáo khoa học: MicroRNA-23a promotes the growth of gastric adenocarcinoma cell line MGC803 and downregulates interleukin-6 receptor pdf

Tài liệu Báo cáo khoa học: MicroRNA-23a promotes the growth of gastric adenocarcinoma cell line MGC803 and downregulates interleukin-6 receptor pdf

... cleavage of mRNA or by inhibi-tion of protein synthesis. On the one hand, computa-tional algorithms have been widely used to predictmiRNA targets. On the other, gene expression profil-ing analysis ... confirm the postulation, wechecked the regulatory effects of miR-23a on the expression of IL6R by RT-PCR and western blot, and found an inverse correlation between miR-23a and IL6R expression ... Both MTT and colony forma-tion assays confirmed the active role of miR-23a in the growth promotion of malignant cells. The fundamental function of miRNAs is to regulatetheir targets by direct...
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Tài liệu Báo cáo khoa học: Multidentate pyridinones inhibit the metabolism of nontransferrin-bound iron by hepatocytes and hepatoma cells docx

Tài liệu Báo cáo khoa học: Multidentate pyridinones inhibit the metabolism of nontransferrin-bound iron by hepatocytes and hepatoma cells docx

... permeability of the Fe–chelator complex.In view of the similar efficacy of the multidentatepyridinones to DFO, further experiments were conductedusing a wider range of pyridinones on normal and Fe-loaded ... C., Hoffbrand, A.V., Kosaryan,M., Olivieri, N.F., Tondury, P. & Wonke, B. (1995) Results of long-term deferiprone (L1) therapy: a report by the Inter-national Study Group on oral iron chelators. ... 1693Effect of chelators and Fe status on subcellular distribu-tion of NTBI in hepatocytes. The effect of the chelators on the intracellular distribution of Fe in normal and Fe-loadedhepatocytes in the...
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Báo cáo y học:

Báo cáo y học: "Eosinopenia is a reliable marker of sepsis on admission to medical intensive care units"

... purposes)Authors' contributionsKA and IK contributed equally to the work. KA and IK draftedthe manuscript and participated in the acquisition of data andthe study design. JB participated in the acquisition of ... draft the manuscript, and participated in the acquisi-tion of data. AZ participated in the coordination of the study.AAZ participated in the design of the study, and performed thestatistical analysis. ... There were no dif-ferences in the leucocyte count between the different groups(one-way analysis of variance, P = 0.095).Concerning the comparison between the noninfected andinfected groups, the...
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Báo cáo y học:

Báo cáo y học: "HLA-DR regulation and the influence of GM-CSF on transcription, surface expression and shedding

... University of Leeds, and PhD in Immunology from University of Liverpool, where she worked on the expression of HLA-DR and the characterisation of the monocyte in patients with sepsis. She is currently ... is a glycosylated cell surface transmembrane protein expressed on antigen-presenting cells and constitutively expressed on monocytes. Expression of HLA-DR by monocytes is essential for the presentation ... Hendry L, Newland AC, Kelsey SM. Administration of recombinant human granulocyte-macrophage colony- stimulating factor after chemotherapy regulates the expression and secretion of monocyte tumor...
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Báo cáo y học:

Báo cáo y học: "Genetic polymorphisms in the nucleotide excision repair pathway and lung cancer risk: A meta-analysis"

... authors, year of publication, ethnic group of the study popula-tion, source of control population, number of geno-typed cases and controls, crude odds ratio (OR) and the method for quality control of ... located in the vicinity of the translation initiation codon, it may alter translation efficiency. The nearby proximal nucleo-tides to the AUG initiation codon are important for the initiation of translation ... precise explanation of the mechanism by which the recognition of the start codon is aided by a purine at position -3 [62], which is the core nucleotide of the Kozak consensus. The polymorphism XPA...
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Tài liệu Báo cáo Y học: A Raman optical activity study of rheomorphism in caseins, synucleins and tau New insight into the structure and behaviour of natively unfolded proteins pot

Tài liệu Báo cáo Y học: A Raman optical activity study of rheomorphism in caseins, synucleins and tau New insight into the structure and behaviour of natively unfolded proteins pot

... acidicconditions are unlikely to alter the conformation signi®-cantly. The backscattered Raman and R OA spectra of the wild-type and mutant tau46 are shown as the top and bottom pairs, respectively, ... onformational elementsare similar and hence that the structures of the caseins,synucleins and tau may be envisaged as more open,hydrated, longer-chain (and nonglobular) versions of the structure of ... structure,possibly b ased on the PPII conformation, and which may b eenvisaged as a more open version of the X -ray crystalstructure of the Bowman±Birk inhibitor. The rheomorphiccharacter i mparted by large...
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Tài liệu Báo cáo Y học: Enhancement by a-tocopheryl hemisuccinate of nitric oxide production induced by lypopolysaccharide and interferon-c through the upregulation of protein kinase C in rat vascular smooth muscle cells docx

Tài liệu Báo cáo Y học: Enhancement by a-tocopheryl hemisuccinate of nitric oxide production induced by lypopolysaccharide and interferon-c through the upregulation of protein kinase C in rat vascular smooth muscle cells docx

... production. The degrees of inhibition of NO production with Ro31-2880 and GF109203X were approximately 70 and 30%, respectively.Effects of TS on the amount of PKCaWe further examined the effects of ... examined only TShas an amphiphilic structure of the polar carboxyl moiety and the hydrophobic isoprene moiety. The enhancing effect of TS on LPS/IFN-induced NO production was inhibitedby the coexistence ... inhepatopoietic and cancer cell lines is caused by the prevention of PKC activity due to activation of PP2A,similar to a-T activation of PP2A [13]. The reason for the inconsistency between our results and...
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Báo cáo Y học: Concerted regulation of free arachidonic acid and hormone-induced steroid synthesis by acyl-CoA thioesterases and acyl-CoA synthetases in adrenal cells pdf

Báo cáo Y học: Concerted regulation of free arachidonic acid and hormone-induced steroid synthesis by acyl-CoA thioesterases and acyl-CoA synthetases in adrenal cells pdf

... [32].Recently, the expression and the activity of differentisoforms of acyl-CoA synthetases was described in the ratliver [37,38]. In addition, a report by Kang [39] implicates the participation of ... compartment of the cell upon hormone treatment.Taken together the results shown here demonstrate the critical role of acyl-CoA synthetases and thioesterases in the regulation of intracellular levels of ... Yamashita, Y. , Fujino, T. &Yamamoto, T.T. (2000) Regulation by adrenocorticotropic hor-mone and arachidonate of the expression of acyl-CoA synthetase4, an arachidonate-preferring enzyme expressed...
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