... Rosemary Jagus2and Orna Elroy-Stein11Cell Research and Immunology, George S. Wise Faculty of Life Sciences, Tel Aviv University, Israel;2Center of Marine Biotechnology, University of Maryland ... significantlyaffected by any of the transfected plasmids, as judged by thedecreased number of cells in S-phase and increased number of polyploid cells. For additional confirmation we checkedthe level of ... study support this idea.Inhibition of PKR activity by over-expression of itsdominant-negative variant PKRD6, or reduction of eIF2aphosphorylation level by over-expression of its variantform,...