... β1.A number of proteinase families are capable of generating the proteolytic fragments of versi‐can. Matrix metalloproteinase (MMP )-1 , -2 , -3 , -7 , and -9 , ADAMTS-1, -4 , -5 and -9 cleaveversican ... types of PGs are chondroitin-sulphate (gly‐curonacid and N-acethylgalactosamine polymer and protein core), dermatan-sulphates(former name chondroitin-sulphate-B, composed of iduronacid and N-acethylgalactosa‐mine ... Angiogenesishttp://dx.doi.org/10.5772/5019813mation of vesicant-HA-CD44 complexes, providing valuable targets against tumor pro‐gression. [13 8-1 40]Emodin (3-methyl-1,6,8-trihydroxyanthraquinone) has evident anti-invasive effect on HA-induced...