... for the other study designs, the results of the two reviewers were averaged. The overall score was the percentage of the maximum possible score, ranging from 0 to 100 percent. The results for ... Labeling The current labeled dosing of hydroxyurea for sickle cell disease calls for the administration of an initial dose of 15 mg/kg/day in the form of a single dose, with monitoring of the patient’s ... clinical trials demonstrated the efficacy of this drug for the treatment of CML, psoriasis, and polycythemia vera. Although there have been reformulations of this drug, there were no labeling revisions...