Crossing the Wires: The Interface between Law and Accounting and the Discourse Theory Potential of Telecommunications Regulation
Báo cáo khoa học: Biochemical evidence for conformational changes in the cross-talk between adenylation and peptidyl-carrier protein domains of nonribosomal peptide synthetases ppt
... because this is the most prominent residue at this position in the closely related A domains of the tyrocidine and bacitracin NRPS Cys331 is part of the binding pocket of the amino acid in the active ... if the binding interface between A and PCP domains is only created for the holo-PCP This would be in agreement with a critical contribution of the Ppant in the interaction of A and PCP domains, ... conformational changes can be monitored via gel-filtration experiments if the overall size and shape of the protein changes Before the analysis, we incubated the apo- and the holo-forms of the A-PCP protein...
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Báo cáo toán học: "The Active Bijection between Regions and Simplices in Supersolvable Arrangements of Hyperplanes" pdf
... the entire active mapping by sign reversals Actually, the active mapping can be refined into an activity preserving bijection between the set of regions and the set of simplices containing no broken ... 3.1 Proof We extend Kn to Kn+1 by adding an extra vertex labelled By adding edges joining to the roots of an increasing spanning forest of Kn , we get a bijection between increasing spanning forests ... forests of Kn and increasing spanning trees of Kn+1 An increasing spanning tree of Kn+1 has its root of degree i if and only if its internal activity for the colexicographic ordering is i, since...
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Báo cáo y học: " Research In silico modeling of the specific inhibitory potential of thiophene-2,3-dihydro-1,5-benzothiazepine against BChE in the formation of β-amyloid plaques associated with Alzheimer''''s disease" doc
... al., In silico modeling of the specific inhibitory potential of thiophene-2,3-dihydro-1,5-benzothiazepine against BChE in the formation of ?-amyloid plaques associated with Alzheimer's disease Theoretical ... whereas the activity of AChE declines BChE may, therefore, play a more prominent role in ACh hydrolysis in the aging brain The presence of BChE in the amyloid plaques and neurofibrillary tangles of ... Compound A in the active sites of ChEs The docking of Compound A with both ChEs has provided valuable information about the nature of the binding interactions of benzothiazepine with these enzymes...
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Báo cáo y học: "Early down-regulation of the pro-inflammatory potential of monocytes is correlated to organ dysfunction in patients after severe multiple injury: a cohort study" pptx
... reasonable to assume that the intensity of monocytic temporal paralysis, that is, the diminished capacity to release proinflammatory cytokines in response to LPS, is in direct proportion to the ... hours after admission In our opinion these findings reflect either the above mentioned refractory state of monocytes towards endotoxin challenge already having released cytokines after the traumatic ... response is initiated to dampen the inflammatory process [3-5] Any imbalance of the tightly regulated homeostasis of pro- and anti-inflammatory forces causes either a hyperinflammatory or an immunosuppressive...
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Studies of the anti cancer potential of flavonoids in human nasopharyngeal carcinoma cells
... C: Insulin and LiCl prevent down-regulation of cyclin D1 induced by luteolin in HK1 cells Fig 3.7D: Insulin and LiCl abrogate the effects of luteolin on CNE2 cells Fig 4.1: Combined effect of ... during the cell cycle where synthesis of both cyclins B1 and B2 is initiated during the interphase and localised in the cytoplasm During the prophase, cyclin B1 migrates from the cytoplasm to the ... indirectly by p16INK4A as the latter binds and inhibits cdk4/6-cyclin D and thus maintains the tumour suppressor activity of pRb through the inhibition of E2F The loss of p16INK4A will inhibit Rb activity,...
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Studies on the anti cancer potential of sesquiterpene lactone parthenolide 1
... Abbreviations xv List of Publications xix CHAPTER INTRODUCTION 1. 1 Parthenolide 1. 1 .1 Introduction: feverfew and Parthenolide 1. 1.2 Chemical structure, metabolism and bioactivities of parthenolide 1. 1.2 .1 ... balance 1. 2 .1 Reactive Oxygen Species 17 1. 2 .1. 1 Definition 17 1. 2 .1. 2 Sources of ROS 18 1. 2.2 Biothiols 19 1. 2.2 .1 Definition 19 1. 2.2.2 Biological properties and metabolism 20 1. 2.3 Anti- oxidant ... Limitations in current study and further directions 18 0 6.5 18 8 6 .1 Conclusions 17 1 17 5 18 4 18 7 CHAPTER REFERENCES ix SUMMARY Parthenolide is the major sesquiterpene lactone responsible for the bioactivities...
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Studies on the anti cancer potential of sesquiterpene lactone parthenolide
... focused on the anti- inflammatory activity of parthenolide On the other hand, the anti- cancer potential of parthenolide has rarely been studied Thus, the main objective of this study is to further ... investigate the anti- cancer potential of parthenolide by studying its sensitization effects on cancer cells in response to death receptor ligands To further validate the anti- cancer property of parthenolide ... al., 2004) However, the anti- cancer potential of parthenolide is still largely unknown Further studies, including both in vitro mechanism studies on anti- cancer potential of parthenolide and in...
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Cognitive differences in collaborative design between architectural and industrial design processes case of building project related product design
... COGNITIVE DIFFERENCES IN COLLABORATIVE DESIGN BETWEEN ARCHITECTURAL AND INDUSTRIAL DESIGN PROCESSES: CASE OF BUILDING PROJECT- RELATED PRODUCT DESIGN LI SUPING (B.Arch, Southeast ... elements of design thinking of an actual building project In the case study of Esplanade-Theatres on the Bay, Singapore, two types of design differences in the collaborative design processes of the project- related ... should examine them at a thinking level, especially on the differences between architectural and industrial design thinking 1.3.4 Thinking level: Design differences between architectural and industrial...
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Báo cáo khoa học: "Augmented Dependency Grammer: A Simple Interface between the Grammer Rule and the Knowledge" pptx
... with the combination of binary case relations, fits the dependency grammar very well, since both dependency and case relation are basically binary The dependency analysis also correlates to the atomic ... hierarchy for concept generalization Atomic f o r m u l a i n FTABLE and THESAURUS Knowledge Base consists of LEXICON, THESAURUS and FTABLE The case grammar, as a basis of internal representation, ... binary relation The semantics in the sense used here may not necessarily be shared among languages, while facts are shared among languages Legato built on the model is syntactic and semantic analysis...
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Báo cáo khoa học: Probing the interface between factor Xa and tissue factor in the quaternary complex tissue factor–factor VIIa–factor Xa–tissue factor pathway inhibitor pptx
... detail the interaction area between sTF and FXa in the quaternary complex than previously carried out This will also allow a comparison of the binding interface between sTF and FXa in the quaternary ... regarding the binding area between sTF and FXa in this complex Regarding the ternary sTF–FVIIa–FX complex other investigators have performed functional analyses to investigate the binding region between ... similarities regarding this interaction area in the quaternary and ternary complexes Increased knowledge about the interface between FX/FXa and TF in these complexes would facilitate the design of...
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minority shareholders protection in shareholding companies a comparison between vietnamese enterprises law and the united kingdom company law
... MINORITY SHAREHOLDERS PROTECTION IN SHAREHOLDING COMPANY – A COMPARISON BETWEEN VIETNAMESE ENTERPRISES LAW AND THE UNITED KINGDOM COMPANY LAW for her master thesis The situation of the research In ... under Vietnamese company law while making a comparision between it and the UK company law In fact, minority shareholder rights are governed by various laws and regulations However, as stated in the ... of the Board of Management have a general power to call all general meetings97 In a situation in which the management harms the company or the shareholders at any time between the regular/annual...
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