... Discussion Summary of main findings Both health- related problems and alcohol intoxications in early adolescence showed influence on frequent alcohol use and initiation of illegal drugs years later, ... behavioural and health problems on late adolescence regular drinking and drug use To explore the impact of gender and early drinking on the relationship between behavioural- , health problems and substance ... 43: 120 5-1 21 2 19 Agrawal A, Grant JD, Waldron M, Duncan AE, Scherrer JF, Lynskey MT, et al: Risk for initiation of substance use as a function of age of onset of cigarette, alcohol and cannabis use: ...