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Development and interpretation of machine learning models for drug discovery

Development and interpretation of machine learning models for drug discovery

Development and interpretation of machine learning models for drug discovery

... concerned with the development and interpretation of machine learning models for drug discovery To this end, it describes the design and application of computational models for specialized use ... focus of this thesis is the development and interpretation of machine learning models for pharmaceutical tasks In drug discovery, project teams usually consist of experts from a variety of disciplines, ... some basic concepts of in silico modeling for drug discovery Concepts Machine learning models for drug discovery mostly try to model the structure-activity relationship of ligand-target interactions...
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Báo cáo khoa học:

Báo cáo khoa học: "A Re-examination of Machine Learning Approaches for Sentence-Level MT Evaluation" ppt

... on one group of MT systems evaluate the translation qualities of new systems? In this paper, we argue for the viability of a regression-based framework for sentence-level MTevaluation Through ... and Chris Brockett 2001 A machine learning approach to the automatic evaluation of machine translation In Proceedings of the 39th Annual Meeting of the Association for Computational Linguistics, ... Koehn 2006 Re-evaluating the role of BLEU in machine translation research In The Proceedings of the Thirteenth Conference of the European Chapter of the Association for Computational Linguistics...
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Báo cáo hóa học:

Báo cáo hóa học: " Development and application of a biomarker assay for determining the pharmacodynamic activity of an antagonist candidate biotherapeutic antibody to IL21R in whole blood" pptx

... biomarkers, and they participated in the data analyses AAH developed the customized Spotfire tool used for data analyses and reviewed statistical analyses YG participated in the assessment and ... assay for determining the pharmacodynamic activity of an antagonist candidate biotherapeutic antibody to IL21R in whole blood Journal of Translational Medicine 2010, 8:51 Page 13 of 13 ... this basic approach (ex vivo stimulation of whole blood) to develop pharmacodynamic biomarker assays for a candidate therapeutic antibody, Ab-01 Ab-01, a human antibody generated by phage display,...
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Báo cáo sinh học:

Báo cáo sinh học: " Development and implementation of explicit computerized protocols for mechanical ventilation in children" pot

... Development and implementation of explicit computerized protocols for mechanical ventilation in children Philippe Jouvet1,2, Patrice Hernert2, and Marc Wysocki2 Pediatric Intensive ... computerized protocols for mechanical ventilation? The human brain has a limited ability to incorporate data and information in decision making and human memory can simultaneously retain and optimally ... making (B) Explicit computerized protocol in open-loop (clinical decision support systems) (C) Explicit computerized protocols in closed-loop Figure The five components of a platform for development...
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Báo cáo khoa học nông nghiệp

Báo cáo khoa học nông nghiệp " The development and implementation of new appropriate technologies for improving goat production and increasing small-holder income in the central region of Vietnam - MS2 " potx

... project The improvement and implementation of new appropriate technologies for improving goat production and increasing small-holder income in the central region of Vietnam (009/05VIE) in Vietnam ... GRRC in the north This aim is reflected in the project title The improvement and implementation of new appropriate technologies for improving goat production and increasing small-holder income in ... 1 Institute Information Project Number & Name Vietnamese Institution The development and implementation of new appropriate technologies for improving goat production and increasing small-holder...
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Project Progress Report: The development and implementation of new appropriate technologies for improving goat production and increasing small-holder income in the central region of Vietnam - MS3

Project Progress Report: The development and implementation of new appropriate technologies for improving goat production and increasing small-holder income in the central region of Vietnam - MS3 " doc

... 1 Institute Information Project Name The development and implementation of new appropriate technologies for improving goat production and increasing small-holder income in the central region of ... improvement and implementation of new appropriate technologies for improving goat production and increasing small-holder income in the central region of Vietnam (009/05VIE) in Vietnam during the period ... The improvement and implementation of new appropriate technologies for improving goat production and increasing small-holder income in the central region of Vietnam This is a program which includes...
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The development and implementation of new appropriate technologies for improving goat production and increasing small-holder income in the central region of Vietnam - Milestone 9

The development and implementation of new appropriate technologies for improving goat production and increasing small-holder income in the central region of Vietnam - Milestone 9" pot

... GRRC in the north This aim is reflected in the project title The improvement and implementation of new appropriate technologies for improving goat production and increasing small-holder income in ... following the introduction of new technologies to farmers in Ninh Thuan, Binh Thuan and Lam Dong provinces of southeast Vietnam The title of the report is New technologies for Improving Goat Production ... for Improving Goat Production in Vietnam English Version Institute Information Project Name The development and implementation of new appropriate technologies for improving goat production and...
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Báo cáo khoa học:

Báo cáo khoa học: "Development and Evaluation of a New Apparatus for Continuous Perfusion of Isolated Perfused Pig Heart" ppt

... An’s Cannula) and the coronary cannula used in the work of Casali et al (B: Casali’s cannula) Development and Evaluation of a New Apparatus for Continuous Perfusion of Isolated Perfused Pig Heart ... frequency of 110 Development and Evaluation of a New Apparatus for Continuous Perfusion of Isolated Perfused Pig Heart 227 Table Isolated heart influx and efflux pH pH of Heart Influx and Efflux ... fibrillated and stopped * : pacemaker on at the frequency of 110 from 50 minutes of perfusion Development and Evaluation of a New Apparatus for Continuous Perfusion of Isolated Perfused Pig Heart...
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Development and implementation of efficient segmentation algorithm for the design of antennas and arrays

Development and implementation of efficient segmentation algorithm for the design of antennas and arrays

... developing the segmentation technique, MBF-PM-AIM is applied to the design of broadband probe-fed antennas and arrays Due to the growing demand of modern wireless communication systems, there is ... enhance the impedance bandwidth of the antennas In this thesis, various wideband semi-circle probe-fed antennas and arrays are developed for wireless local area network These include the semi-circle ... for the Green’s function for fast evaluation of the MoM matrix elements and the computation of the radiation patterns Finally, a patch antenna is analyzed to demonstrate the accuracy of the algorithm...
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Development and application of hybrid finite methods for solution of time dependent maxwells equations

Development and application of hybrid finite methods for solution of time dependent maxwells equations

... domain finite methods for the numerical solution of time dependent Maxwell’s equations The two finite methods focused are FDTD and FETD methods The applications of the developed hybrid methods are ... analysis of passive microwave circuits and studies in dosimetry and tissue interaction CHAPTER TIME DOMAIN FINITE METHODS FOR SOLUTION OF MAXWELL’S EQUATIONS 2.1 Maxwell’s Equations The physics of time ... equivalence of FDTD and a particular case of FETD method a stable hybrid 3-D FETD-FDTD method was proposed The focus of this thesis is in the development and subsequent applications of efficient hybrid time...
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Development and application of advanced proteomic techniques for high throughput identification of proteins

Development and application of advanced proteomic techniques for high throughput identification of proteins

... DEVELOPMENT AND APPLICATION OF ADVANCED PROTEOMIC TECHNIQUES FOR HIGHTHROUGHPUT IDENTIFICATION OF PROTEINS HU YI (B.Sc.) A THESIS SUBMITTED FOR THE DEGREE OF DOCTOR OF PHILOSOPHY DEPARTMENT OF ... analysis of proteins, i.e proteomics (Pandey and Mann, 2000; Tyers and Mann, 2003) Therefore, the advancement of proteomics relies largely on the development of state -of- the-art proteomics techniques ... study, we sought to develop and apply advanced proteomic techniques from three different aspects for high- throughput identification of enzymes and their associated proteins in yeast proteome (catalomics)...
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Tài liệu Báo cáo khoa học:

Tài liệu Báo cáo khoa học: "Collecting a Why-question corpus for development and evaluation of an automatic QA-system" pdf

... which are not asked, and also contain practical examples Human-powered answers often contain unrelated information and discourselike elements Additionally, the answers not always have a connection ... it alone, or that Mr X and Ms Y are known enemies The problem of several possible answers and, in consequence, automatic evaluation has been tackled for years within another field of study: automatic ... required for automatic data quality control Conclusions In this paper we have described a dynamic and inexpensive method of collecting a corpus of questions and answers using the Amazon Mechanical...
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