Identification and molecular interacting network of the conserved oligomeric golgi (COG) tethering complex

... on the new naming system, as in Chapter and the corresponding publication ( The binary interacting network of the conserved oligomeric Golgi (COG) tethering complex , Loh and Hong 2004) COG and ... dimers, or they come in the form of large heterooligomeric complexes such as the conserved oligomeric Golgi (COG) complex and several other tethering complexes which have been identified and are ... Publications This thesis is written based on the four first author papers listed below (1-4) 1) Loh, E and Hong, W The binary interacting network of the conserved oligomeric Golgi (COG) tethering complex...

Báo cáo khoa học: NMR and molecular dynamics studies of an autoimmune myelin basic protein peptide and its antagonist Structural implications for the MHC II (I-Au)–peptide complex from docking calculations ppt

... various systems comprised 3899 and 4516 SPC molecules for the agonist and the antagonist in water, respectively, and 817 and 927 Me2SO molecules for the agonist and the antagonist, respectively, corresponding ... the binding and afﬁnity for I-Au because of occupation of the P1 pocket Recent thermodynamic and kinetic studies of the binding of TCRs to peptide MHC ligands suggested that the low afﬁnity of ... (1999) Design and synthesis of a potent cyclic analogue of the myelin basic protein epitope MBP72-85: importance of the Ala81 carboxyl group and of a cyclic conformation for induction of experimental...

Molecular dynamics simulations of the tensile and melting behaviours of silicon nanowires

... atoms near the surface, as compared with those in the bulk, and the increasing dominance of the surface would decrease the strength of the structure 3.2 The melting properties of the SiNWs The variation ... materials [36] The change of the melting temperature of nanostructures depends on their surface This indicates that the unstable surface of free-standing nanowires leads to a decrease in the melting ... understand the melting behaviour of SiNWs, the structural evolution of the nanowire with the diameter of 3.32 nm at different temperatures in the heating process is shown in Fig Before the melting...

Báo cáo hóa học: " Mapping of immunogenic and protein-interacting regions at the surface of the seven-bladed β-propeller domain of the HIV-1 cellular interactor EED" pptx

... our mapping of the MA binding site on the EED linear sequence, since β-strands d were the most exposed β-strands at the periphery of the β-propeller (Fig 2D) Of note, the upper face of the β-propeller ... β-propeller domain of EED and protein-interacting regions Figure Surface representation of the β-propeller domain of EED and protein-interacting regions The binding residues of HIV-1 proteins are ... Thus, at the early phase of the HIV-1 life cycle, EED might play a role in targeting the regions of proviral DNA integration into the host chromatin At the late steps of the virus replication cycle,...

Báo cáo hóa học: "Molecular Dynamics Simulations of the Roller Nanoimprint Process: Adhesion and Other Mechanical Characteristics" pot

... simulation of the RNIL process The objectives of this study are to understand the deformation behavior of imprinted ﬁlm and the effect of adhesion and friction with changes of the roller tooth ... of 0.002° per time step The unit of time step was 10-15 s The characteristic width and height of the roller tooth were both nm The roller was composed of 11294 atoms The width and height of the ... on the Au substrate One is the ‘‘pushed behavior’’ that occurs on the substrate atoms that are located on the left side of the roller, and the other is the ‘‘pulled behavior’’ that occurs on the...

Báo cáo khoa hoc:"Mapping the Naked Neck (NA) and Polydactyly (PO) mutants of the chicken with microsatellite molecular markers" docx

... genetic map of the chicken, and open the way to the identification of the molecular nature of two developmental mutations of the chicken that are known to occur in many breeds of chickens chicken ... both the former “classical” map and the molecular map, and to lead the way to the molecular identification of mutations with major phenotypic effects Molecular mapping of a mutant can be done in the ... sire alleles from the dams allele 83 Mapping naked neck and polydactyly in chicken Table II Linkage mapping of the naked neck mutation (N A) with four microsatellite markers on chicken chromosome...

Báo cáo sinh học: " Molecular cloning and partial sequence characterization of the duplicated amylase genes from Drosophila erecta" pps

... ancient trait The copies of the a -amylase gene from a strain of D melanogaster have already been partly sequenced (Boer and Hickey, 1986), and the coding regions showed a high degree of sequence similarity ... to be the same in the copies of each species, this would support the hypothesis of recombination events occuring between the copies of the gene within a locus We cloned both copies of the amylase ... erecta and D melanogaster An alignment of the D erecta amylase sequences with the proximal amylase of the D melanogaster strain Oregon R is presented in Fig The time of divergence between the species,...

Identification and molecular characterisation of simian malaria parasites in wild monkeys of singapore

... constitue the first report of the prevalence of malaria infection in Singapore s macaques, but also help in expanding our current understanding on the epidemiology of P knowlesi in Singapore 20 CHAPTER ... human cases and the infected macaques, indicating that the cases had acquired the infection in the vicinity where these monkeys were found [20] The finding of P knowlesi in Singapore is of no surprise ... IDENTIFICATION AND MOLECULAR CHARACTERIZATION OF SIMIAN MALARIA PARASITES IN WILD MONKEYS OF SINGAPORE LI MEIZHI IRENE (B.Sci (Hons.)), NUS A THESIS SUBMITTED FOR THE DEGREE OF MASTER OF SCIENCE...

The cult of guangze zunwang and its religious network in the chinese diaspora, 19th century 2009

... prompted the establishment of Guangze Zunwang temples in the two host countries This study examines the cult of Guangze Zunwang and its religious network connecting Southeast China and the Chinese ... examines the cult of Guangze Zunwang and its religious network connecting Southeast China and the Chinese communities in Singapore and Malaysia as they overlap with the larger forces of In this ... local cults in general and the cult of Guangze Zunwang in particular continue to be the bond between the ethnic Chinese overseas and their ancestral homeland in Southeast China This study examines...

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Molecular characterization and developmental expression patterns of the zebrafish twist gene family

... pattern with other species 83 4.5.1 Zebrafish twist1 a and twist1 b genes 83 4.5.2 Zebrafish twist2 85 4.5.3 Zebrafish twist3 86 4.6 Shared and unique expression sites of the zebrafish twist genes 86 ... proteins generated by the neighbor-joining method Figure 3.6: Gene structure of twist1 a, twist1 b, twist2 and twist3 Figure 3.7: RT-PCR of zebrafish twist genes Figure 3.8: Expression of zebrafish twist ... medaka, and human twist genes showed that the zebrafish twist1 a and twist1 b are coparalogs and co-orthologs of human TWIST1 Furthermore, zebrafish twist1 a and twist1 b are orthologous to medaka twist1 a...

Báo cáo y học: "omparative Efficacy and Tolerability of 5-Loxin® and Aflapin® Against Osteoarthritis of the Knee: A Double Blind, Randomized, Placebo Controlled Clinical Study"

... prove the efficacy and tolerability of Aflapin in osteoarthritis Hence in the present clinical study we sought to evaluate the comparative efficacy and tolerability of 5-Loxin® and Aflapin® in the ... (e) in placebo, 100 mg/ day 5-Loxin® and 100 mg/day Aflapin® groups, respectively to 5, represent days of evaluations such as day 0, day 7, day 30, day 60 and day 90, respectively Each bar represents ... Broad spectrum safety of Aflapin was also established in a battery of acute and sub-acute toxicity studies in rat and rabbits These findings altogether motivated us to evaluate efficacy of Aflapin...

Báo cáo y học: "Characterization of N200 and P300: Selected Studies of the Event-Related Potential Salil H. Patel 1 and Pierre N. Azzam 2"

... months time [10 2] Acute cortical damage to auditory processing structures might be assessed objectively in a complementary manner, via studies of the MMN [10 3] 15 2 10 11 12 13 14 15 16 17 18 Closing ... Shappell SA, Brandt ME Psychophysiology of N200/ N400: A review and classification scheme Advances in Psychophysiology 19 91; 4:43 -10 6 Hoffman JE Event-related potentials and automatic and controlled ... stimulus, and omitted-stimulus paradigms Brain Topography 19 98; 11 :14 1 -15 1 67 Polich J, Hoffman D P300 and handedness Psychophysiology 19 88; 35:497-507 68 Hopper KD, Patel S, Cann TS, et al The relationship...

Teachers’ and teacher evaluators’ perceptions of the current teacher evaluations and teaching assessment criteria

... student problems - the teacher understands and can explain the plan - the lesson plan shows a good understanding of the methodology During the lesson – teaching and learning Teaching the lesson excellent ... students and keeps them interested - There is a good balance of teacher talking time and student talking time - the teacher encourages and praises - the teacher considers the feelings of the students ... - The teacher starts the lesson clearly - The teacher uses the lesson plan appropriately - The teacher uses a good balance of English and Vietnamese - There are clear stages to the lesson - the...

Tài liệu Đàn tính The Marvelous and Sarced Musical Instrument of the Tay People- La Công ý pptx

... play the đàn tính Participants can imagine the terrain of the spirit army’s march by watching the instru- la: sacred musical instrument of the tày people | 283 ment and the position of the Then’s ... avoid the sacred đàn tính Even the Then say that they la: sacred musical instrument of the tày people | 281 were hesitant to touch the đàn tính before they were initiated, and many had never played ... inhabit the Then’s đàn tính When Mrs Kịt agreed to sell her third đàn tính to the Vme, she figure Calabash used to make the body of the đàn tính are dried on a shelf above the hearth La Công Ý, Vme...

Tài liệu THE ELDERLY AND MOBILITY: A REVIEW OF THE LITERATURE pdf

... Transport Research Library and is Australia’s major transport database As well as the holdings of the ARRB Transport Research Library collection, it also includes the holdings of a number of other ... match the characteristics and travel needs of the road users that use it It is recommended that: Road design and operation standards be adopted that reflect the needs and capabilities of older road ... accessible, affordable, safe and co-ordinated transport options that are tailored to the needs of older adults and promotion and awareness of alternative transport options amongst older drivers and their...

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