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Multifunctional nanoparticles of biodegradable polymers for diagnosis and treatment of cancer

Multifunctional nanoparticles of biodegradable polymers for diagnosis and treatment of cancer

Multifunctional nanoparticles of biodegradable polymers for diagnosis and treatment of cancer

... MULTIFUNCTIONAL NANOPARTICLES OF BIODEGRADABLE POLYMERS FOR DIAGNOSIS AND TREATMENT OF CANCER PAN JIE (M ENG., TIANJIN UNIVERSITY) A THESIS SUBMITTED FOR THE DEGREE OF DOCTOR OF PHILOSOPHY ... nanoparticles of biodegradable polymers for QDs formulation for targeted and sustained imaging for cancer diagnosis at its early stage Two polymers of poly(lactide)-vitamin E TPGS (PLA-TPGS) and vitamin ... loading QDs for targeted and sustained imaging for cancer diagnosis at its early stage 4) to prepare biodegradable polymeric multifunctional nanoparticles for targeted chemotherapy and imaging...
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Nanoparticles of biodegradable polymers for controlled and targeted delivery of protein drugs and small molecule drugs

Nanoparticles of biodegradable polymers for controlled and targeted delivery of protein drugs and small molecule drugs

... NANOPARTICLES OF BIODEGRADABLE POLYMERS FOR CONTROLLED AND TARGETED DELIVERY OF PROTEIN DRUGS SMALL AND MOLECULE DRUGS BY LEE SIE HUEY (B.Sc (Hons.), NUS) A THESIS SUBMITTED FOR THE DEGREE OF ... backbone of PLA and PLGA to form PLA-TPGS and PLGA-TPGS block copolymers These block copolymers are an example of amphiphiles Their uses as different carriers for delivery of protein and anticancer ... Peptide /protein drug delivery 15 2.2.1 Structural aspect of protein 15 2.2.2 Challenges in peptide /protein drug delivery 17 2.2.3 Approaches for delivery of peptide /protein drugs...
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Acute and Chronic Sinusitis - A Practical Guide for Diagnosis and Treatment docx

Acute and Chronic Sinusitis - A Practical Guide for Diagnosis and Treatment docx

... sinus ostia to allow adequate drainage and aeration • Senior BA, Kennedy DW Management of sinusitis in the asthmatic patient AAAI J,1996;77: 6-1 9 0031003 Development of Sinuses • Maxillary and ethmoid ... appropriate laboratory and imaging studies, and when indicated screen patients for allergy • Prescribe appropriate medication regimens for acute and chronic sinusitis • Know of the relationships ... rhinitis is rare • Nasal discharge and congestion are prominent symptoms of sinusitis • Nasal mucosa and sinus mucosa are similar and are contiguous 0031003 Scope of Sinusitis • Affects 3 0-3 5 million...
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Nanomedicine  multifunctional nanoparticles of biodegradable polymers for cancer treatment

Nanomedicine multifunctional nanoparticles of biodegradable polymers for cancer treatment

... NANOMEDICINE: MULTIFUNCTIONAL NANOPARTICLES OF BIODEGRADABLE POLYMERS FOR CANCER TREATMENT LIU YUTAO (B.Sc., Fudan University) A THESIS SUBMITTED FOR THE DEGREE OF DOCTOR OF PHILOSOPHY ... development of cutting-edge nanoparticles of biodegradable polymers with overall fascinating performance demonstrates the progress in the field of nanomedicine for cancer treatment viii NOMENCLATURE ... 173 LIST OF PUBLICATIONS 193 vi SUMMARY Multifunctional nanocarriers have been regarded as potent candidates for efficient cancer nanomedicine Nanoparticles of biodegradable polymers...
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Nanoparticles of biodegradable polymers for delivery of therapeutic agents and diagnostic sensitizers to cross the blood brain barrier (BBB) for chemotherapy and MRI of the brain

Nanoparticles of biodegradable polymers for delivery of therapeutic agents and diagnostic sensitizers to cross the blood brain barrier (BBB) for chemotherapy and MRI of the brain

... Functions of the Blood Brain Barrier The main function of the blood brain barrier is to protect the brain The BBB serves as an impermeable wall to prevent the entry of agents from outside of the brain ... Anatomy of the Blood Brain Barrier 1.1.2 Functions of the Blood Brain Barrier 1.1.3 Clinical Significance of the Blood Brain Barrier 1.2 METHODS TO OVERCOME THE BLOOD BRAIN BARRIER 1.3 NANOPARTICLES ... polymers to deliver drugs across the blood brain barrier and the surface coating plays key roles in determining the extent of the particles to cross the BBB To further investigate the potential for the...
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Trastuzumab decorated nanoparticles of biodegradable polymers for targeted small molecule chemotherapy

Trastuzumab decorated nanoparticles of biodegradable polymers for targeted small molecule chemotherapy

... (PLGA/MMT) nanoparticles decorated by trastuzumab for targeted chemotherapy of breast cancer Biomaterials 2008; 29(4): 475-486 Sun B, Feng SS Trastuzumab decorated nanoparticles for targeted chemotherapy ... conjugation of trastuzumab on NP surface for targeted drug delivery Experiments were carried out to investigate the feasibility of the obtained NPs for targeted delivery of small molecule drugs The trastuzumab ... objective of this research is to study the effectiveness of two systems of trastuzumabfunctionalized nanoparticles for targeted drug delivery In the first part, a novel system of trastuzumab- decorated...
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Paclitaxel loaded nanoparticles of biodegradable polymers for cancer chemotherapy

Paclitaxel loaded nanoparticles of biodegradable polymers for cancer chemotherapy

... PACLITAXEL LOADED NANOPARTICLES OF BIODEGRADABLE POLYMERS FOR CANCER CHEMOTHERAPY KHIN YIN WIN (M Sc., NUS) A THESIS SUBMITTED FOR THE DEGREE OF DOCTOR OF PHILOSOPHY DEPARTMENT OF CHEMICAL ... potential analysis of various formulations of paclitaxel- loaded PLGA nanoparticles 81 Figure 13 XRD analyses of paclitaxel, TPGS, blank PLGA nanoparticles and paclitaxel- loaded PLGA nanoparticles ... of paclitaxel- loaded PLGA nanoparticles, fluorescent PLGA nanoparticles and standard PS nanoparticles 133 Table Surface chemistry of the formulation materials and the paclitaxel- loaded PLGA nanoparticles...
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Nanoparticles of biodegradable polymers for gene therapy of hepatitis b

Nanoparticles of biodegradable polymers for gene therapy of hepatitis b

... DNA: NANOPARTICLES < /b> OF < /b> BIODEGRADABLE < /b> POLYMERS < /b> FOR < /b> GENE < /b> THERAPY < /b> OF < /b> HEPATITIS < /b> B JUNPING WANG (B Eng., ZJU, China) A THESIS SUBMITTED FOR < /b> THE DEGREE OF < /b> MASTER OF < /b> SCIENCE GRADUATE PROGRAM IN BIOENGINEERING ... gastrointestinal (GI) barrier and blood brain barrier, thus can benefit oral gene < /b> delivery and brain gene < /b> delivery vii LIST OF < /b> FIGURES AND TABLES Fig.2.1 Basic components of < /b> cationic lipids (DC-Chol) ... most of < /b> the current polymers < /b> for < /b> gene < /b> delivery Finally, the author discussed the application of < /b> biodegradable < /b> nanoparticles < /b> for < /b> gene < /b> delivery which is viewed as the most promising field for < /b> current...
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Nanoparticles of biodegradable polymers for delivery of diagnostic therapeutic agents their potential application in brain cancer therapy

Nanoparticles of biodegradable polymers for delivery of diagnostic therapeutic agents their potential application in brain cancer therapy

... NANOPARTICLES OF BIODEGRADABLE POLYMERS FOR DELIVERY OF DIAGNOSTIC/ THERAPEUTIC AGENTS: THEIR POTENTIAL APPLICATION IN BRAIN CANCER THERAPY YU QIANRU (B.Eng, Southeast ... Limitations in Modern Chemotherapy 2.2 Brain Cancers and Blood Brain Barrier (BBB) 2.2.1 Brain cancers and cancer treatment 2.2.2 Introduction to the blood brain barrier 2.2.2.1 History of blood brain ... the delivery of therapeutic agents into the brain Paclitaxel, one of the most widely used anti -cancer drugs, has limited application in treating brain tumor because of the existence of BBB Of...
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Báo cáo y học:

Báo cáo y học: "The feasibility of axial and coronal combined imaging using multi-detector row computed tomography for the diagnosis and treatment of a primary spontaneous pneumothora" pps

... this article as: Kim: The feasibility of axial and coronal combined imaging using multi-detector row computed tomography for the diagnosis and treatment of a primary spontaneous pneumothorax Journal ... Conclusions The combined axial- coronal HRCT increased the sensitivity of the preoperative detection of ELCs Coronal imaging alone was not significantly better than axial imaging alone The coronal imaging ... accurate examination of ELCs HRCT is traditionally performed by axial imaging Although axial imaging has the advantage of the central and peripheral areas being observed simultaneously, it is perpendicular...
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cáo khoa học:

cáo khoa học: " The European Society of Human Reproduction and Embryology guideline for the diagnosis and treatment of endometriosis: an electronic guideline implementability appraisal" ppsx

... Sweden, the Netherlands, and New Zealand Appraisal of the guideline We asked the panel members to read the ESHRE guideline for the diagnosis and treatment of endometriosis and to assess it with the ... and CM appraised the guideline with eGLIA and participated in the telephone conference and the revision of the manuscript RH participated in the design of the study and the revision of the manuscript ... Discussion The aim of this study was to investigate the implementability of the ESHRE guideline for the diagnosis and treatment of endometriosis with the aid of the eGLIA tool In general, the appraisers...
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BETWEEN TWO WORLDS: AN EXPLORATION OF PRIVACY MANAGEMENT ISSUES ARISING FOR FIRST-YEAR COLLEGE STUDENTS DEALING WITH A MOTHER‟S BREAST CANCER DIAGNOSIS AND TREATMENT

BETWEEN TWO WORLDS: AN EXPLORATION OF PRIVACY MANAGEMENT ISSUES ARISING FOR FIRST-YEAR COLLEGE STUDENTS DEALING WITH A MOTHER‟S BREAST CANCER DIAGNOSIS AND TREATMENT

... Transitions and Privacy Changes Impact of Breast Cancer and Changes in Family Privacy .8 Parents‟ Communication with their College Students 13 Interface of Privacy Transitions in College ... adjustment to college also adds another complex dimension to the already stressful diagnosis of parental breast cancer within the family The private and intimate nature of a breast cancer diagnosis ... Organization, The Wellness Company, The Little Red Door Cancer Agency, Cancer Care, Inc., Revolution Health Group, National Breast Cancer, Cancer Compass, Susan G Komen for the Cure, and Dana Faber...
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identification, design and synthesis of oxygenated hydrocarbon-based carbon dioxide-soluble polymers for chemical and petroleum engineering applications

identification, design and synthesis of oxygenated hydrocarbon-based carbon dioxide-soluble polymers for chemical and petroleum engineering applications

... ABSTRACT IDENTIFICATION, DESIGN AND SYNTHESIS OF OXYGENATED HYDROCARBON-BASED CO2-SOLUBLE POLYMERS FOR CHEMICAL AND PETROLEUM ENGINEERING APPLICATIONS Lei Hong, Ph.D University of Pittsburgh, 2006 ... defended on March 29, 2006 and approved by Dr Eric J Beckman, Professor, Chemical and Petroleum Engineering Department Dr J Karl Johnson, Professor, Chemical and Petroleum Engineering Department ... Professor, Department of Chemistry Dissertation Director: Dr Robert M Enick, Chairman and Professor, Chemical and Petroleum Engineering Department ii Copyright © by Lei Hong 2006 iii ABSTRACT IDENTIFICATION,...
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synthesis and characterization of novel polymers for functional and stimuli responsive silicon surfaces

synthesis and characterization of novel polymers for functional and stimuli responsive silicon surfaces

... ProQuest Information and Learning Company 300 North Zeeb Road P.O Box 1346 Ann Arbor, MI 48106-1346 Synthesis and Characterization of Novel Polymers for Functional and Stimuli Responsive Silicon Surfaces ... Modification of Silicon/ SiO2 Surfaces with TTMS and Random Copolymers 241 241 241 242 Results and Discussion 7.4.1 Synthesis of TTMS 7.4.2 Synthesis of Poly(EHAM-co-AIEMA) 7.4.3 Silicon/ SiO2 ... describes the synthesis and characterization of novel amphiphilic block copolymers used as stimuli responsive coatings on surfaces The behavior of surfaces covalently modified with these copolymers...
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The Use of Selected Medicinal Herbs for Chemoprevention and Treatment of Cancer, Parkinson’s Disease, Heart Disease, and Depression

The Use of Selected Medicinal Herbs for Chemoprevention and Treatment of Cancer, Parkinson’s Disease, Heart Disease, and Depression

... in the diet have any positive benefits for patients afflicted with early stages of Parkinson’s disease? This is 11 Use of Selected Medicinal Herbs for Chemoprevention 263 remarkable in light of the ... of sodium and then an increase in the intracellular concentration of calcium (Sanborn, 2007) The increased myocardial 11 Use of Selected Medicinal Herbs for Chemoprevention 267 uptake of calcium ... 2004), it is not known whether digoxin will remain as the standard therapy for heart failure (Hauptman and Kelly, 1999) In the future, there might be other uses for digitoxin There is evidence that...
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