Mathematical model of outer hair cells in the cochlea
Mathematical model of outer hair cells in the cochlea
... property of the outer hair cell 22 Chapter 3: Mathematical Model of Outer Hair Cell Chapter Mathematical Model of Outer Hair Cell The mathematical model of the outer hair cell is presented in this ... obtained, providing a prerequisite for a better understanding of the dynamics of the in vivo OHC embedded in the cochlea By including the stiff constraint of the reticular lamina on the OHC, the ... developed mathematical models of the outer hair cell is given The detailed mathematical formulation used in the present model is then described Lastly, parameters in the model are determined and...
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Role of SPHK2S1P signalling in regulating mitochondrial function in the MPTP induced mouse model of parkinsons disease and in the MPP treated MN9D cells
... Possible role of sphingosine kinase 2/S1P signaling in promoting mitochondrial function in the MPTPinduced mouse model of Parkinson’s disease and in MPP+ - treated MN9D cells (Manuscript in Press) in ... changes observed in the MPTP- induced mouse model of Parkinson’s disease 102 4.2 Expression pattern of TH and DAT in the MPTP induced mouse model 103 4.3 Proinflammatory cytokine TNFα was ... implicated in PD pathogenesis, the expression pattern of TNFα and iNOS in the SNc of the MPTP- induced mouse model was analysed It was observed that there was an increase in the levels of XX TNF and iNOS...
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Báo cáo hóa học: " Spontaneous voltage oscillations and response dynamics of a Hodgkin-Huxley type model of sensory hair cells" ppt
... basis of Equation for a random Gaussian force that was band-limited to 200 Hz and had a standard deviation of σs = pN (b) Sensitivity as a function of the amplitude of the sinusoidal external ... model as a function of frequency This was done using Equation and a Gaussian external force that was band-limited to 200 Hz and had a standard deviation of pN For each choice of the parameters, ... that fluctuations can lead to drastic qualitative changes in the receptor potential dynamics In particular, the voltage dynamics became chaotic in a wide area of parameter space For a cell deep...
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Báo cáo y học: "Nature of Regulatory T Cells in the Context of Allergic Disease." ppsx
... Ozdemir et al, Regulatory T Cells in the Context of Allergic Disease The mechanisms by which SIT has its effects include the very early desensitization effect The regulation of Tcell responses by generation ... et al, Regulatory T Cells in the Context of Allergic Disease thus preventing the activation of mast cells and basophils IgG4 has been shown to reduce the IgE-mediated degranulation of these cells ... amounts of IL-4 and IL-10.35 Further studies are required to elucidate the in vivo role of these cells and their subsets Effects of SIT on Dendritic Cells To understand the mechanisms of action of...
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Báo cáo y học: "Regulating the immune system: the induction of regulatory T cells in the periphery Jane H Buckner1 and Steven F Ziegler2" pot
... site is not known — whether these cells exist only transiently then die, whether they persist in the body as TR cells, or whether they return to their previous role as nonregulatory resting T cells ... development of CD4+CD25+ TR cells may occur in the periphery in man Induction of CD4+CD25+ TR cells in the periphery The induction of TR cells that resemble the ‘natural’ or thymically derived TR cells ... death, TR cells lead to the induction of T regulator (Tr1) cells and Th3 cells, which feed back to inhibit inflammation, and the TR cells inhibit proliferation of antigen-specific and bystander...
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The role of CD8 t cells in the differentiation of TNF iNOS producing dendritic cells and TH1 responses
... supported by studies demonstrating the involvement of CD8 T cells in the generation of protective CD4 Th1 responses during retroviral infection (Peterson et al., 2002) Importantly, CD8 T cells ... depletion of CD8 T cells abrogated the protective Th1 response induced by DNA vaccination (Gurunathan et al., 2000), suggesting that CD8 T cells were vital for the polarization of Th1 cells This ... unprecedented ability to activate naive T cells (Steinman and Cohn, 1974) These cells are now known as the primary instigators of the adaptive immunity as they are vital for detecting, alerting and...
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Báo cáo y học: "Hedgehog overexpression leads to the formation of prostate cancer stem cells with metastatic property irrespective of androgen receptor expression in the mouse model" pps
... from the AR+ luminal cell population [9] In other words, AR signalling may be entirely bypassed during the transformation of prostate stem cells into PCSCs [9] Alternatively, AR signalling may remain ... basal /stem cells, supporting that they could be the origin of PCSCs under the influence of persistent Hedgehog overexpression P63+ basal /stem cells were transformed into AR+ or ARcancer cells ... overexpression To understand whether P63+ basal /stem cells were activated under the influence of Hedgehog overexpression, we examined the pCX-shh-IG-injected prostates during the progression of PIN toward...
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Báo cáo y học: " Mathematical model of blunt injury to the vascular wall via formation of rouleaux and changes in local hemodynamic and rheological factors. Implications for the mechanism of traumatic myocardial infarction" pot
... blood flow and located in the "hemodynamic shade" of the original attached rouleaux The escalating formation of rouleaux continues within the entire "hemodymanic shade" zone The model of traumatic ... understanding of the mechanism of blunt trauma to the vascular wall, which takes into account local hemodynamic and rheological factors, can be summarized in the following way Trauma leads to the ... [4] Therefore, in accordance with the above, trauma may create transient conditions for the formation of rouleaux or for the interlacing of existing rouleaux that have formed in the flowing blood...
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Transplantation of mesenchymal stem cells for the treatment of parkinsons disease in a mouse model
... TRANSPLANTATION OF MESENCHYMAL STEM CELLS FOR THE TREATMENT OF PARKINSON’S DISEASE IN A MOUSE MODEL CHAO YIN XIA MD A THESIS SUBMITTED FOR THE DEGREE OF DOCTOR OF PHILOSOPHY DEPARTMENT OF ANATOMY ... MPTP, an acute insult initiates an inflammatory reaction that becomes self sustaining after the initiating agent has disappeared The MPTP model of PD has been invaluable in the studying of the ... cell transplantation attenuates blood brain barrier damage and neuroinflammation and protects dopaminergic neurons against MPTP toxicity in the substantia nigra in a model of Parkinson’s disease...
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Pulmonary tuberculosis associated with increased number and percentage of natural killer and B cells in the peripheral blood pot
... detected in this study The most notable findings were increased < /b> percentage < /b> with < /b> an absolute numbers of < /b> NK and < /b> B cells while reduced percentage < /b> with < /b> an absolute numbers of < /b> CD4 + lymphocytes in the peripheral ... the comparison of < /b> the absolute number < /b> of < /b> various peripheral blood lymphocyte subsets between the PTB patients and < /b> normal healthy individuals The absolute numbers of < /b> NK cells (p = 0.000) and < /b> the ... peripheral blood of < /b> patients with < /b> PTB A variety of < /b> immune abnormalities of < /b> the peripheral blood lymphocyte subsets including NK cells in PTB have already been described in PTB (Snyder et al., 2007; Barcelos...
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Báo cáo sinh học: " The Israeli strain IS-98-ST1 of West Nile virus as viral model for West Nile encephalitis in the Old World" pdf
... study was limited in its scope, the results indicate that WNV strain IS-98-ST1 is suitable as viral model for West Nile encephalitis in the Old World The Israeli strain IS-98-ST1 that caused the ... the fact that an Israeli WNV strain was introduced in New York City in 1999 [4] The murine model of WNV-associated encephalitis has been widely used to address the viral pathogenesis[5] Strains ... 1998, as well as WNV strains present in North America does contrast with the low pathogenicity of most ancestral strains of WNV[18,19] In conclusion, the Israeli strain IS-98-ST1 of WNV provides...
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Báo cáo sinh học: " Re-evaluating the role of natural killer cells in innate resistance to herpes simplex virus type 1" pot
... as the basis for concluding that NK cells play no role in innate resistance to HSV-1 Likewise, we question the validity of comparisons of HSV-1 infection in mice that exhibit "high" or "low" natural ... NK cells are dispensable for the innate resistance of mice to HSV-1 infection, further investigation is necessary to determine what role, if any, NK cells play in human resistance to HSV-1 infection ... NK cells and/or professional APCs confer innate resistance to HSV-1 infection via the secretion of IFN-γ at early times p.i The following study was initiated to determine if NK cells provide innate...
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báo cáo hóa học: " A role for DNA-dependent activator of interferon regulatory factor in the recognition of herpes simplex virus type 1 by glial cells" pot
... this article as: Furr et al.: A role for DNA-dependent activator of interferon regulatory factor in the recognition of herpes simplex virus type by glial cells Journal of Neuroinflammation 2 011 ... III-transcribed RNA intermediate Nat Immunol 2009, 10 :10 65 -10 72 55 Melchjorsen J, Rintahaka J, S by S, Horan KA, Poltajainen A, Østergaard L, Paludan SR, Matikainen S: Early innate recognition of herpes simplex ... simplex virus in human primary macrophages is mediated via the MDA5/MAVSdependent and MDA5/MAVS/RNA polymerase III-independent pathways J Virol 2 010 , 84 :11 350 -11 358 Page 12 of 12 doi :10 .11 86 /17 42-2094-8-99...
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Từ khóa: identification of neural stem cells in the drosophila larval brainfunction of data link layer in the isoosi reference modelrole of glial cells in the formation and maintenance of synapsesrole of glial cells in the nervous systemexploiting dendritic cells in the development of cancer vaccinesfunction of glial cells in the brainrole of glial cells in the brainrole of fetal liver cells in restoration of the liver cell functionsthe role of nkt cells in the immune regulation of neoplastic diseaseby inkt cells in the pathogenesis of primary biliary cirrhosis pbcmathematical model of the translational microtransducerimaging hematopoietic stem cells in the marrow of long bones in vivorole of stem cells in the conversion of pancreas to livercd25 cd127 t cells by ido cho cells in the peripheral blood of breast cancer patientscd4 t cells in the spleens of ad5 il17a transduced miceBáo cáo thực tập tại nhà thuốc tại Thành phố Hồ Chí Minh năm 2018Nghiên cứu tổ hợp chất chỉ điểm sinh học vWF, VCAM 1, MCP 1, d dimer trong chẩn đoán và tiên lượng nhồi máu não cấpGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitNGHIÊN CỨU CÔNG NGHỆ KẾT NỐI VÔ TUYẾN CỰ LY XA, CÔNG SUẤT THẤP LPWAN SLIDEQuản lý hoạt động học tập của học sinh theo hướng phát triển kỹ năng học tập hợp tác tại các trường phổ thông dân tộc bán trú huyện ba chẽ, tỉnh quảng ninhPhối hợp giữa phòng văn hóa và thông tin với phòng giáo dục và đào tạo trong việc tuyên truyền, giáo dục, vận động xây dựng nông thôn mới huyện thanh thủy, tỉnh phú thọTrả hồ sơ điều tra bổ sung đối với các tội xâm phạm sở hữu có tính chất chiếm đoạt theo pháp luật Tố tụng hình sự Việt Nam từ thực tiễn thành phố Hồ Chí Minh (Luận văn thạc sĩ)Phát triển du lịch bền vững trên cơ sở bảo vệ môi trường tự nhiên vịnh hạ longNghiên cứu về mô hình thống kê học sâu và ứng dụng trong nhận dạng chữ viết tay hạn chếTìm hiểu công cụ đánh giá hệ thống đảm bảo an toàn hệ thống thông tinSở hữu ruộng đất và kinh tế nông nghiệp châu ôn (lạng sơn) nửa đầu thế kỷ XIXTổ chức và hoạt động của Phòng Tư pháp từ thực tiễn tỉnh Phú Thọ (Luận văn thạc sĩ)Quản lý nợ xấu tại Agribank chi nhánh huyện Phù Yên, tỉnh Sơn La (Luận văn thạc sĩ)Tranh tụng tại phiên tòa hình sự sơ thẩm theo pháp luật tố tụng hình sự Việt Nam từ thực tiễn xét xử của các Tòa án quân sự Quân khu (Luận văn thạc sĩ)Chiến lược marketing tại ngân hàng Agribank chi nhánh Sài Gòn từ 2013-2015Đổi mới quản lý tài chính trong hoạt động khoa học xã hội trường hợp viện hàn lâm khoa học xã hội việt namMÔN TRUYỀN THÔNG MARKETING TÍCH HỢPQUẢN LÝ VÀ TÁI CHẾ NHỰA Ở HOA KỲ