... primary blasts Haematologica 2008, 93:662-669 34 Sharma SV, Haber DA, Settleman J: Cell < /b> line-based platforms to < /b> evaluate the < /b> therapeutic efficacy of < /b> candidate anticancer agents Nat Rev Cancer < /b> ... Gautschi O, Mack PC, Davies AM, Lara PN, Gandara DR: Aurora < /b> kinase inhibitors: a < /b> new class of < /b> targeted drugs in < /b> cancer < /b> Clin Lung Cancer < /b> 2006, 8:93-98 Page 10 of < /b> 10 37 Mazzino A,< /b> Muratore-Ginanneschi ... frequencies of < /b> polyploidy Conveniently, it is < /b> standard clinical practice to < /b> perform karyotyping on hematological < /b> cancer < /b> cells and chromosome < /b> number < /b> can serve as an attractive resistance marker...