Modulation of west nile virus capsid protein and viral RNA interaction through phosphorylation 1
Modulation of west nile virus capsid protein and viral RNA interaction through phosphorylation 1
... West Nile virus capsid protein attenuates its interaction with viral RNA 14 th International Congress of Virology, Istanbul Cheong, Y.K and Ng M.L (2008) West Nile Virus capsid protein and RNA interaction ... Introduction………………………………………………….……… .1 1.2 West Nile virus epidemiology………………… …………….………… 1. 3 Virus morphology…………………………………………….………….4 1. 4 West Nile virus RNA genome organization and viral proteins ……… 1. 4 .1 Structural proteins… ... localization…… … 18 1. 6.4 Capsid (C) protein and RNA interaction … ……20 1. 6.5 1. 7 Structure of capsid (C) protein …………………………… .14 Phosphorylation of capsid (C) protein and its effects 22...
- 44
- 304
- 0
Modulation of west nile virus capsid protein and viral RNA interaction through phosphorylation 2
... A-sense RNA UTR+C R RNA 1F RNA 1R RNA 2F RNA 2R RNA 3F RNA 3R RNA 4F RNA 4R RNA 5F RNA 5R RNA 6F RNA 6R RNA 7F RNA 7R RNA 8F RNA 8R RNA 9F RNA 9R RNA 10F RNA 10R RNA 11F RNA 11R RNA 12F RNA 12R A-sense ... Appendix 3B | Materials and methods 32 Table 2- 3 List of the names of primers used and its purpose No 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 ... 5758-67 72 of viral RNA Synthesize fragment 6 728 -77 42 of viral RNA Synthesize fragment 7698-87 02 of viral RNA Synthesize fragment 8655-9669 of viral RNA Synthesize fragment 9613-10617 of viral RNA...
- 51
- 244
- 0
Modulation of west nile virus capsid protein and viral RNA interaction through phosphorylation 3
... most often Fragment 13 and 14 are anti-sense fragments of Fragments and 12 This suggests that C protein binding sites on the WNV RNA are found in the regions of - 2 934 and 96 13 - 11057 of the ... of myc-C protein and synthesized viral RNA in BHK cells (A) Visualization of myc-C protein and transfected viral RNA in BHK cells with fluorescence microscopy Plasmid encoding myc-C protein and ... 11057 of the WNV RNA genome | Results 82 4 .3 Defining the West Nile virus (WNV) RNA- binding region on the capsid (C) protein Although the Kunjin virus RNA- binding region on the C protein had previously...
- 27
- 165
- 0
Modulation of west nile virus capsid protein and viral RNA interaction through phosphorylation 4
... histidine-tagged C (His-C) protein (Lane 3) |Results 105 5.3 Phosphorylation of the West Nile virus (WNV) capsid (C) protein 5.3.1 West Nile virus (WNV) capsid (C) protein is a phosphoprotein In order ... transfected 293FT 48 hr 55 kDa 43 kDa 34 kDa 26 kDa 17 kDa 55 kDa 43 kDa 34 kDa 26 kDa 17 kDa 22 125 5.5 Phosphorylation of West Nile virus (WNV) capsid (C) protein diminishes over time If phosphorylation ... functions of C protein then the phosphorylation status of C protein should be dynamic If the role of phosphorylation is to prevent premature association of viral RNA or even cellular RNA with C protein...
- 47
- 214
- 0
Modulation of west nile virus capsid protein and viral RNA interaction through phosphorylation 5
... (19 85) Sequence analysis of the viral core protein and the membrane-associated proteins V1 and NV2 of the flavivirus West Nile virus and of the genome sequence for these proteins Virology 1 45, ... localisation of C protein could indirectly prevent premature C protein and RNA association, although direct regulation of C protein and RNA interaction was achieved through phosphorylation of C protein Phosphorylation ... protein and RNA interaction and how phosphorylation might affect this interaction in vitro, interaction between C protein and viral RNA needs to be characterized Although the delineation of RNA...
- 34
- 185
- 0
Báo cáo y học: "A VLP-based vaccine targeting domain III of the West Nile virus E protein protects from lethal infection in mice" pptx
... injections of the vaccine completely protected mice from a lethal WNV challenge, even when given in the absence of any adjuvant The relatively low production costs of the DIII-C-AP205 vaccine, ... uses thereof 2007 doi: 10.1186/1743-422X-7-146 Cite this article as: Spohn et al., A VLP-based vaccine targeting domain III of the West Nile virus E protein protects from lethal infection in ... shown by immunization of mice with recombinant domain III of the WNV E protein [21] The increased immunogenicity of the domain III by conjugation to the VLP carrier may therefore be sufficient to...
- 9
- 272
- 0
Báo cáo sinh học: " The Israeli strain IS-98-ST1 of West Nile virus as viral model for West Nile encephalitis in the Old World" pdf
... study was limited in its scope, the results indicate that WNV strain IS-98-ST1 is suitable as viral model for West Nile encephalitis in the Old World The Israeli strain IS-98-ST1 that caused the ... the fact that an Israeli WNV strain was introduced in New York City in 1999 [4] The murine model of WNV-associated encephalitis has been widely used to address the viral pathogenesis[5] Strains ... 1998, as well as WNV strains present in North America does contrast with the low pathogenicity of most ancestral strains of WNV[18,19] In conclusion, the Israeli strain IS-98-ST1 of WNV provides...
- 5
- 403
- 0
Báo cáo y học: "Ocular Manifestations of West Nile Virus Infection" doc
... Ben Yahia S, Ladjimi A, et al Chorioretinal involvement in patients with West Nile virus infection Ophthalmology 2004;111:2065-70 Garg S, Jampol LM Systemic and intraocular manifestations of West ... routine evaluation of patients with clinically suspected WNV infection References Hayes EB, Gubler DJ West Nile virus: epidemiology and clinical features of an emerging epidemic in the United States ... early diagnosis of the disease while serologic testing is pending Therefore, an ocular examination, including ophthalmoscopy and FA in selected cases, should be part of the routine evaluation of...
- 2
- 473
- 0
báo cáo khoa học: "Prognosis of West Nile virus associated acute flaccid paralysis: a case series" pdf
... root inflammation of the cauda equina, thus a diagnosis of West Nile virus acute flaccid paralysis was made The patient was discharged home after 10 days in the hospital Following discharge she ... forms of West Nile virus neuroinvasive disease, most cases of acute flaccid paralysis occur in healthy, non-elderly individuals [9,17,18], although advanced age may be associated with an increased ... baseline function The PCS and MCS outcomes can be found in Table Summary of Cases The mean age of those with acute flaccid paralysis was 61 years [SD, 7] Most patients with acute flaccid paralysis...
- 6
- 287
- 0
báo cáo khoa học: "A nano-view of West Nile virus-induced cellular changes during infection" pps
... ultra-structural studies Results and Discussion West Nile (Sarafend) virus-induced changes in infected cells at late stage infection At the late stages of West Nile (Sarafend) virus infection in Vero ... Journal of Nanobiotechnology 2004, 2:6 http://www.jnanobiotechnology.com/content/2/1/6 Figure height scan of West Nile virus-infected Vero cells at 24 h p.i (a) AFM1 (a) AFM height scan of West Nile ... Journal of Nanobiotechnology 2004, 2:6 http://www.jnanobiotechnology.com/content/2/1/6 Figure height scan of West Nile virus – infected Vero cells at 12 h p.i (a) AFM2 (a) AFM height scan of West Nile...
- 7
- 188
- 0
Báo cáo y học: " The natural history of West Nile virus infection presenting with West Nile virus meningoencephalitis in a man with a prolonged illness: a case report" doc
... as: Mainali et al.: The natural history of West Nile virus infection presenting with West Nile virus meningoencephalitis in a man with a prolonged illness: a case report Journal of Medical Case ... progression of WNND Case presentation A 56-year-old African-American man with a history of hypertension and chronic hepatitis C virus infection presented to the emergency room with a three-day history of ... alternative methods of diagnosis would be helpful in prompt management of the disease In our patient, we found that the brain MRI findings (bilateral edema and hyperintensity of the basal ganglia and...
- 4
- 310
- 0
Báo cáo y học: " First serological evidence of West Nile virus in human rural populations of Gabon" pdf
... residental and migratory birds [23] In conclusion, this first serological survey of West Nile virus in Gabonese human populations shows widespread circulation of this virus Further investigations are ... Transmission dynamics and changing epidemiology of West Nile virus Anim Health Res Rev 2008, 9:71-86 Mathiot CC, Georges AJ, Deubel V: Comparative analysis of West Nile virus strains isolated from human ... Deubel V: The ecology and epidemiology of West Nile virus in Africa, Europe and Asia Curr Top Microbiol Immunol 2002, 267:195-221 Rappole JH, Hubalek Z: Migratory birds and West Nile virus J Appl Microbiol...
- 3
- 314
- 0
Báo cáo khoa học: "Diversification of West Nile virus in a subtropical region" pptx
... similar to a strain isolated during an outbreak in Israel during 1998 [4] and was considered to be the dominant variant circulating through North America until 2002 During that year, a variant arose ... 5'-CCTTGGAGCAGTGCTGGAAGTA-3' (1636–1657) 5'-CGGCTCATACATAAGCGCGAT-3' (5085–5105) 5'-TTCCACAAAGGTCGAGCTAGG-3' (5514–5534) 5'-CCATCTGCAGTGACAGCAGCTA-3' (5950–5971) 5'-TGTTCCCTTCAGCTGCAACTT-3' (1834–1854) ... corresponding to its arrival in naïve populations The large numbers of birds affected in the initial introduction in the New York City area, in particular crows and a variety of exotic birds, were accompanied...
- 9
- 229
- 0
Báo cáo khoa học: "Diversification of West Nile virus in a subtropical region" potx
... similar to a strain isolated during an outbreak in Israel during 1998 [4] and was considered to be the dominant variant circulating through North America until 2002 During that year, a variant arose ... 5'-CCTTGGAGCAGTGCTGGAAGTA-3' (1636–1657) 5'-CGGCTCATACATAAGCGCGAT-3' (5085–5105) 5'-TTCCACAAAGGTCGAGCTAGG-3' (5514–5534) 5'-CCATCTGCAGTGACAGCAGCTA-3' (5950–5971) 5'-TGTTCCCTTCAGCTGCAACTT-3' (1834–1854) ... corresponding to its arrival in naïve populations The large numbers of birds affected in the initial introduction in the New York City area, in particular crows and a variety of exotic birds, were accompanied...
- 9
- 262
- 0
Từ khóa: a the geographic distribution of domestic animal cases of west nile virus in the united statesb the geographic distribution of bird cases of west nile virus in the united stateswest nile virus basic principles replication mechanism immune response and important geneticrecommendations for prevention and control of hepatitis c virus hcv infection andcarcinogens in foods occurrence modes of action and modulation of human risks by genetic factors and dietary constituents6microbial modulation of nf kappa b signaling commensals and pathogensv malagón o finzi pv vidari g armijos c zaragoza t 2007 an ethnobotanical survey of medicinal plants used in loja and zamora chinchipe ecuador j ethnopharmacol 111 1 pp 63 81c reactive protein and risk of lung cancerrecommendations for prevention and control of hepatitis c virus infectionprogress toward prevention and control of hepatitis c virus infectionrecommendations for prevention and control of hepatitis c virusprevention and control of hepatitis c virusprediagnostic leptin adiponectin creactive protein and the risk of postmenopausal breast cancerc reactive protein and risk of breast cancerwhere is the source of the nile river in which direction does it flow and where is its deltaNghiên cứu sự biến đổi một số cytokin ở bệnh nhân xơ cứng bì hệ thốngBáo cáo quy trình mua hàng CT CP Công Nghệ NPVNghiên cứu tổ hợp chất chỉ điểm sinh học vWF, VCAM 1, MCP 1, d dimer trong chẩn đoán và tiên lượng nhồi máu não cấpMột số giải pháp nâng cao chất lượng streaming thích ứng video trên nền giao thức HTTPGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitPhối hợp giữa phòng văn hóa và thông tin với phòng giáo dục và đào tạo trong việc tuyên truyền, giáo dục, vận động xây dựng nông thôn mới huyện thanh thủy, tỉnh phú thọTrả hồ sơ điều tra bổ sung đối với các tội xâm phạm sở hữu có tính chất chiếm đoạt theo pháp luật Tố tụng hình sự Việt Nam từ thực tiễn thành phố Hồ Chí Minh (Luận văn thạc sĩ)Nghiên cứu về mô hình thống kê học sâu và ứng dụng trong nhận dạng chữ viết tay hạn chếĐịnh tội danh từ thực tiễn huyện Cần Giuộc, tỉnh Long An (Luận văn thạc sĩ)Thiết kế và chế tạo mô hình biến tần (inverter) cho máy điều hòa không khíSở hữu ruộng đất và kinh tế nông nghiệp châu ôn (lạng sơn) nửa đầu thế kỷ XIXTổ chức và hoạt động của Phòng Tư pháp từ thực tiễn tỉnh Phú Thọ (Luận văn thạc sĩ)Kiểm sát việc giải quyết tố giác, tin báo về tội phạm và kiến nghị khởi tố theo pháp luật tố tụng hình sự Việt Nam từ thực tiễn tỉnh Bình Định (Luận văn thạc sĩ)Quản lý nợ xấu tại Agribank chi nhánh huyện Phù Yên, tỉnh Sơn La (Luận văn thạc sĩ)Giáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtGiáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtChiến lược marketing tại ngân hàng Agribank chi nhánh Sài Gòn từ 2013-2015MÔN TRUYỀN THÔNG MARKETING TÍCH HỢPTÁI CHẾ NHỰA VÀ QUẢN LÝ CHẤT THẢI Ở HOA KỲ