... molecule probes for proteomics applications”, Appl Genomics Proteomics, 2003, in press Tan, E.L.P., Panicker, R.C., Tan, L.P., Chattopadhaya, S., Yao, S.Q Developing chemical biology tools for the study ... be analyze by 2D-GE, thereby rendering the technique insufficient for large- scale protein profiling in human 1.2 Addressing the proteomic challenges In this section, two strategies that have been ... quantification Image overlay Image subtraction Figure Strategy of 2D DIGE 1.2.2 Sub- proteomic expression profiling of proteins using activity-based probes (ABPs) As mentioned before, more than 100 000 proteins...