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Development of NMR methods for the structural elucidation of large proteins

Development of NMR methods for the structural elucidation of large proteins

Development of NMR methods for the structural elucidation of large proteins

... DEVELOPMENT OF NMR METHODS FOR THE STRUCTURAL ELUCIDATION OF LARGE PROTEINS ZHENG YU (B.Sc., Xiamen University) A THESIS SUBMITTED FOR THE DEGREE OF DOCTOR OF PHILOSOPHY DEPARTMENT OF BIOLOGICAL ... analysis of complex, x    Development of NMR methods for the structural elucidation of large proteins Summary   crowded and folded high-dimensional spectra On the basis of this software platform, ... 199 xii    Development of NMR methods for the structural elucidation of large proteins List of Figures   List of Figures  Figure 1.1: The flowchart of protein structure determination by NMR Figure...
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nmr methods for the investigation of structure and transport

nmr methods for the investigation of structure and transport

... number of spins By linearity of the Fourier transform the direct relation between the peak integral and the number of spins of the corresponding chemical group holds for the spectrum of superposed ... derivation due to the time-dependence of the unit vectors Using the product rule for the derivation and the fact that the time derivative of the unit vector is the cross product of !rf with this ... expressions Qn and MCk the naturals n and k signify the index of the result and measured data vectors, respectively The latter results from the discretization of e.g kx in (2.38) For the sake of completeness,...
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Development of computational methods for the rapid determination of NMR resonance assignment of large proteins

Development of computational methods for the rapid determination of NMR resonance assignment of large proteins

... determination is the spectral assignment procedure This involves sequence-specific resonance assignment of NMR signals and the assignment of NOESY spectra Resonance assignment forms the basis for characterizing ... obtain the assignments of the Cα and CO of the same residue Then, the CO frequency is used to obtain assignments for the HN and 15N of residue (i+1) with the HNCO experiment Finally, the NH and ... applications for solution NMR 1.3.2 TROSY triple -resonance experiments for resonance assignments of large proteins NMR experiments provide a set of unique combinations of neighboring resonance spin...
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Báo cáo y học:

Báo cáo y học: "Classification methods for the development of genomic signatures from high-dimensional data" potx

... evaluation of the performance of a classification algorithm The SN is the proportion of correct positive classifications out of the number of true positives The SP is the proportion of correct ... classifications out of the number of true negatives The accuracy is the total number of correct classifications out of the total number of samples The PPV is the probability that a patient is ... We define the prediction accuracy of the ensemble by majority voting as: Ar = P (Y ≥ k + 1) Accuracy of classification algorithms for the van de Vijver et al [17] data Figure Accuracy of classification...
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Part   development of novel methods for the synthesis of homoallylic alcohols part II  multigrams synthesis of ( ) epibatidine

Part development of novel methods for the synthesis of homoallylic alcohols part II multigrams synthesis of ( ) epibatidine

... 25 25 25 Time (h) 2.0 5.0 6.0 1.5 5.0 2.0 Yield %b (1 03:10 4) (E/Z)c 25 (1 00: 0) (8 0/2 0) 23 (1 00: 0) (8 0/2 0) 25 (7 6:2 4) (8 0/2 0) 45 (1 00: 0) (8 0/2 0) 49 (1 00: 0) (8 0/2 0) 69 (1 00: 0) (8 0/2 0) 105 105a 105b ... Yield 9a (% ) ( : ) (E/Z) 15 (7 5:2 5) (1 00/ 0) 22 (2 3:7 7) (8 0/2 0) 40 (9 9: 1) (8 2/1 8) 55 (1 00: 0) (8 0/2 0) 69 (1 00: 0) (8 0/2 0) OH 105f Yield 11f (% ) 13 28 23 10 The investigations on the effects of solvent ... Synthetic Route 183 iii SUMMARY PART I: Development of Novel Methods for the Synthesis of Homoallylic Alcohols In the development of novel methods for the synthesis of homoallylic alcohols, two conceptual...
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Comparison of Methods for the Extraction of Bioflocculants from Activated Sludge

Comparison of Methods for the Extraction of Bioflocculants from Activated Sludge

... an effort to develop an effective extraction method for bioflocculants from the microbial cell surface Materials and Methods Activated sludge samples Activated sludge samples were collected from ... was the most effective extraction method for activated sludge However, cell disruption is not effective for the isolation of bioflocculants Thus, NaOH extraction was the most effective method for ... polymer extraction methods (steaming extraction, NaOH extraction, SDS extraction, and washing extraction) were compared to develop an effective extraction method for bioflocculants from activated sludge...
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Tài liệu Báo cáo khoa học:

Tài liệu Báo cáo khoa học: "Methods for the Qualitative Evaluation of Lexical Association Measures" doc

... qualitative evaluation of lexical association measures, mainly for the following reasons: the instability of precision values obtained from the rst few percent of the data in the SLs; the lack of signicant ... precision values above 50% for the rst 10% of the list, but is outperformed by the t-test afterwards Looking at the rst 40% of the data, there is a big gap between the good measures (t-test, ... identication of between 75% (AdjN) and 80% (PNV) of the TPs (ii) For the rst 40% of the SLs, and lead to the worst results, with outperforming 10% 20% 30% -test 40% 50% 60% 70% 80% 90% 100% part of signicance...
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Báo cáo khoa học:

Báo cáo khoa học: "INIGATION OF PROCESSING STRATEGIES FOR THE STRUCTURAL ANALYSIS OF ARGOMF" pdf

... is found, all of them can be picked up Then the father must stack up to De evidence for same future proposition level is open for further expansion To determine the appropriateness of this algorithm ... the top of the tree, for are evidence Consider L to De a the tree, representing the lowest that can receive more evidence to dummy) For every node NEN on the the following: Another use of clues ... propositions Note then that we not expect to add evidence for a brother or uncle of L - these nodes are closed off, as only the last brother of any particular Notation: in the following discussion...
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báo cáo hóa học:

báo cáo hóa học: " The evolution of methods for the capture of human movement leading to markerless motion capture for biomechanical applications" pptx

... University of California [5,6] provided a tremendous resource of knowledge related to the mechanics of human movement The work at the University of California formed the basis for many of the fundamental ... factors limiting the advancement of the study of human movement is the measurement of skeletal movement from markers or sensors placed on the skin The movement of the markers is typically used to ... term markerless motion capture Markerless methods for human motion capture Motion capture is an important method for studies in biomechanics and has traditionally been used for the diagnosis of the...
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Cocoa Processing Methods for the Production of High Quality Cocoa in Vietnam ppt

Cocoa Processing Methods for the Production of High Quality Cocoa in Vietnam ppt

... with the Vietnamese research Institutes involved Success Alliance is also thanked for their assistance in providing information regarding the cocoa industry in Vietnam and in the establishment of ... darken in colour during drying as the majority of browning reactions will occur during this process DRYING OF COCOA Drying of cocoa is an important step in cocoa processing as some of the reactions ... get air into the fermenting cocoa and to help make the fermentation even throughout the cocoa When more air gets into the cocoa, as a result of turning, the rate of fermentation will increase...
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Báo cáo hóa học:

Báo cáo hóa học: " Research Article Fixed Point Methods for the Generalized Stability of Functional Equations in a Single Variable" ppt

... for some functional equations in a single variable We prove the generalized Ulam-Hyers stability of the single variable equation w◦f ◦η f h 1.8 As an application of our result for 1.8 , the stability ... the stability of monomial functional equations, Fixed Point a Theory, vol 8, no 2, pp 201–218, 2007 25 V Radu, The fixed point alternative and the stability of functional equations, Fixed Point ... transformations,” Bulletin of the American Mathematical Society, vol 57, pp 223–237, 1951 Z Gajda, “On stability of additive mappings,” International Journal of Mathematics and Mathematical Sciences, vol...
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Standard Methods for the Examination of Water and Wastewater P3

Standard Methods for the Examination of Water and Wastewater P3

... American Water Works Association, Water Environment Federation Standard Methods for the Examination of Water and Wastewater Organism Water boatman Water dog Water fern Water hyacinth Watermeal Water ... American Water Works Association, Water Environment Federation Standard Methods for the Examination of Water and Wastewater Algae General TAYLOR, W.R 1957 Marine Algae of the Northeastern Coast of ... Association, American Water Works Association, Water Environment Federation Standard Methods for the Examination of Water and Wastewater Organism Snails Soft-rayed fish Soft-shelled clam Sowbug...
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Standard Methods for the Examination of Water and Wastewater P2

Standard Methods for the Examination of Water and Wastewater P2

... Standard Methods for the Examination of Water and Wastewater Synedra © Copyright 1999 by American Public Health Association, American Water Works Association, Water Environment Federation Standard ... the Examination of Water and Wastewater Pandorina © Copyright 1999 by American Public Health Association, American Water Works Association, Water Environment Federation Standard Methods for the ... of Water and Wastewater Synura © Copyright 1999 by American Public Health Association, American Water Works Association, Water Environment Federation Standard Methods for the Examination of Water...
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