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Characterization of CD137 ligand mediated human monocyte differentiation and their effects on t cell activities

Characterization of CD137 ligand mediated human monocyte differentiation and their effects on t cell activities

Characterization of CD137 ligand mediated human monocyte differentiation and their effects on t cell activities

... contrast to these T cell stimulatory activities, CD137L stimulated monocytes also induce T cell apoptosis CD137 mediated, monocyte dependent T cell apoptosis requires direct cell to cell contact and ... myelopoiesis to generate myeloid cells for resolution of an infection 15    Introduction 1.2.4.2 Effects of CD137L stimulation in monocytes Studies have shown that the activation of CD137L on monocytes ... INTRODUCTION   Introduction This thesis focuses on the activities of CD137 ligand (CD137L) activation on monocytes, a subtype of myeloid cells Hence, this introduction gives an overview of the protein...
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Báo cáo Y học: Tyrosine sulfation and N-glycosylation of human heparin cofactor II from plasma and recombinant Chinese hamster ovary cells and their effects on heparin binding pot

Báo cáo Y học: Tyrosine sulfation and N-glycosylation of human heparin cofactor II from plasma and recombinant Chinese hamster ovary cells and their effects on heparin binding pot

... modifications on heparin binding, recombinant CHO cells were treated with inhibitors of tyrosine sulfation and N-glycosylation under conditions that allowed partial inhibition of these modifications ... In summary, we present evidence for a very strong similarity of HCII from human serum and its recombinant counterpart from CHO cells with respect to tyrosine sulfation and N-glycosylation The remarkable ... of posttranslational modifications of human HCII from circulating blood and genetically modified CHO cells and their effects on heparin binding All three potential N-glycosylation sites were found...
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synthesis of hematite (r-fe2o3) nanorods diameter-size and shape effects on their

synthesis of hematite (r-fe2o3) nanorods diameter-size and shape effects on their

... the concentration of HCHO gas, which is certainly scientifically and technically interesting Conclusions In summary, we have described in this paper the shapecontrolled synthesis of hematite (R-Fe2O3) ... the formation of porous R-Fe2O3 and reminiscent of the orientation-ordered nanostructures for R-Fe2O3 in air conditions based on the combined analysis of DrTGA and TEM results Additionally, it ... provides not only the first example of investigating the magnetic property evolution of nanorods/ nanowire diameters and porosity, but also the first example of the fabrication of hematite nanostructure...
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Báo cáo khoa học: Temperature and salts effects on the peptidase activities of the recombinant metallooligopeptidases neurolysin and thimet oligopeptidase pdf

Báo cáo khoa học: Temperature and salts effects on the peptidase activities of the recombinant metallooligopeptidases neurolysin and thimet oligopeptidase pdf

... Dependence of the hydrolysis reaction rates by neurolysisn and TOP on concentration and chemical nature of salts The dependence of the rate constants according to the concentration and the chemical ... NaCl concentration, and the extent of it was dependent on the substrate (Table 4) and on the nature of the salts (Fig 2) Therefore, the structures of TOP and neurolysin could be changed by salts, ... Val position in order to verify the inuence of the nature of the amino acid at this position on determination of the cleavage sites and on the amount of their hydrolysis This series of peptides...
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Report to the Congress on Practices of the Consumer Credit Industry in Soliciting and Extending Credit and their Effects on Consumer Debt and Insolvency pot

Report to the Congress on Practices of the Consumer Credit Industry in Soliciting and Extending Credit and their Effects on Consumer Debt and Insolvency pot

... BOARD OF GOVERNORS OF THE FEDERAL RESERVE SYSTEM Report to the Congress on Practices of the Consumer Credit Industry in Soliciting and Extending Credit and their Effects on Consumer Debt and Insolvency ... (FDIC), Report to the Congress on Practices of the Consumer Credit Industry 23 the National Credit Union Administration, the Office of the Comptroller of the Currency (OCC), and the Office of Thrift ... discussion of marketing and solicitation of credit cards is in Board of Governors, Further Restrictions on Unsolicited Offers Report to the Congress on Practices of the Consumer Credit Industry 21 The...
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Báo cáo Y học:Association of the thyrotropin receptor with calnexin, calreticulin and BiP Effects on the maturation of the receptor docx

Báo cáo Y học:Association of the thyrotropin receptor with calnexin, calreticulin and BiP Effects on the maturation of the receptor docx

... enhances the degradation of TSHR (Fig 4) The association with CNX and/ or CRT therefore seems contribute to the stability and/ or the maturation of the TSHR To obtain further insights into the contribution ... amount of receptor was coimmunoprecipitated with CNX and CRT than with BiP Effects of interactions between TSHR and CNX and CRT We then attempted to determine the effects of these interactions on the ... chaperones and TSHR RESULTS Synthesis, maturation and degradation of TSHR at the endoplasmic reticulum level To study the maturation of TSHR after its synthesis, K562 cells stably transfected with...
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Mechanisms of polymer ca2+ interaction and their effects on the characteristics of alginate microspheres and films 3

Mechanisms of polymer ca2+ interaction and their effects on the characteristics of alginate microspheres and films 3

... with Ca2+ Their presence could hinder the formation of the ‘egg box’ structure with alginate Therefore interactions between alginate and pectin are likely to occur along some segments of the polymer ... proportion of alginate to copolymer and the moisture sorption ability of the individual polymer components Drug release across the alginate matrix was affected by varying the type and amount of copolymer ... sodium alginate and the Ca2+ was very rapid and the affinity of alginate for Ca2+ was much greater than the other copolymers, thus forming insoluble calcium alginate immediately upon contact with Ca2+...
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Mechanisms of polymer ca2+ interaction and their effects on the characteristics of alginate microspheres and films  2

Mechanisms of polymer ca2+ interaction and their effects on the characteristics of alginate microspheres and films 2

... the pH of the medium used promoted interactions between Ca2+ and alginate The displacement of Ca2+ by H+ could be controlled by careful manipulation of the pH of the medium The FTIR spectra of ... and the properties of the matrix to different extents Unravelling the cross-linking mechanisms and their effects on matrix integrity would assist in the control of the interaction between Ca2+ ... 1 .23 88 .23 ± 3.16 29 74.40 ± 1 12. 15 65.71 ± 0.39 CAI 0 .25 59.00 ± 1. 62 86.56 ± 4.67 26 46.34 ± 79.91 73.55 ± 0.48 CAI 0.35 66 .22 ± 2. 21 87 .23 ± 2. 13 22 10.71 ± 22 0.17 76 .24 ± 0. 72 CAI 0 .25 S - 84.51...
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Mechanisms of polymer ca2+ interaction and their effects on the characteristics of alginate microspheres and films 1

Mechanisms of polymer ca2+ interaction and their effects on the characteristics of alginate microspheres and films 1

... 81. 73 ± 2.58 92.43 ± 1. 89 +13 .09 2337.26 ± 72.52 3236 .16 ± 11 3.36 +38.46 18 .64 ± 1. 10 10 .15 ± 1. 16 -8.49 MP 87. 91 ± 2.48 10 2.08 ± 2.50 +16 .12 2302.57 ± 74 .10 3346.87 ± 98.26 +45.35 25 .18 ± 1. 48 ... -16 .74 NI 57.50 ± 1. 91 100.69 ± 2.69 +75 .11 19 55. 71 ± 56.47 3409 .17 ± 86.02 +74.32 19 .68 ± 1. 53 11 .68 ± 0.77 -8.00 FL 55.27 ± 1. 90 90. 91 ± 0.85 +64.48 217 5.76 ± 43.68 2952.56 ± 71. 65 +35.70 14 .92 ... between the viscosity of sodium alginate and the Ca2+ content, indicating a strong influence of the polymer viscosity on the extent of cross-linking in the microspheres In film formation, the sodium...
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Báo cáo khoa học: Characterization of sequence variations in human histone H1.2 and H1.4 subtypes pptx

Báo cáo khoa học: Characterization of sequence variations in human histone H1.2 and H1.4 subtypes pptx

... arginine may affect the secondary structure of the C-terminal tail and the binding of H1.4 to chromatin, as arginine offers additional hydrogen-bonding abilities to DNA as compared to lysine ... cell lines was extracted by using the DneasyTM tissue kit (Qiagen, Hilden, Germany) and examined for sequence variations in codon 18 of H1.2 and in codon 174 of H1.4 To obtain the frequency of the ... human tumor cell lines By using HILIC we detected amino acid substitutions in H1.2 and H1.4 at the protein level In addition, sequencing of the corresponding gene segments confirmed these findings...
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Báo cáo y học:

Báo cáo y học: " Functional characterization of two newly identified Human Endogenous Retrovirus coding envelope genes" docx

... tissues tested, without any specificity for the placenta Among the 16 coding env genes of the human genome tested in [8], only two, namely envW (syncytin-1) and envFRD (syncytin-2), had been found ... the cytotrophoblast cells to form the syncytiotrophoblast layer The two newly identified env genes were therefore similarly tested To so, they were first cloned and introduced into a eukaryotic ... characteristic pattern of the two previously described fusogenic syncytin-1 and syncytin-2 gene products- is not fusogenic In this respect, these results suggest that the two newly identified envV and...
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Spectroscopic and Microscopic Investigation of Gold NanoparticleFormation: Ligand and Temperature Effects on Rate and Particle Size

Spectroscopic and Microscopic Investigation of Gold NanoparticleFormation: Ligand and Temperature Effects on Rate and Particle Size

... migration of thiolated ligands would lead to less particle organization Correlation of Particle Size and Size Dispersion with Rate of Nucleation and Growth Time We have discussed the nanoparticle ... nucleation and growth processes The temperature effects on particle size and size dispersion also can be interpreted based on the rate of nucleation and growth processes At lower temperatures of 25 and ... formation process dependence on concentration of stabilizing ligand (ODT) present and solution temperature In this section, we discuss the correlation of these reaction parameters with the size and...
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Tài liệu Báo cáo khoa học: The isolation and characterization of cytochrome c nitrite reductase subunits (NrfA and NrfH) from Desulfovibrio desulfuricans ATCC 27774 Re-evaluation of the spectroscopic data and redox properties ppt

Tài liệu Báo cáo khoa học: The isolation and characterization of cytochrome c nitrite reductase subunits (NrfA and NrfH) from Desulfovibrio desulfuricans ATCC 27774 Re-evaluation of the spectroscopic data and redox properties ppt

... describes the relationship between the heme core description and the spectroscopic and redox properties of each identified heme from the NrfHA complex Conclusions D desulfuricans ATCC 27774 ccNiR ... this communication, we report for the first time the isolation and biochemical characterization of D desulfuricans ATCC 27774 ccNiR subunits The stoichiometry between NrfH and NrfA is discussed The ... (2003) Cytochrome c nitrite reductase ˜ from Desulfovibrio desulfuricans ATCC 27774 The relevance of the two calcium sites in the structure of the catalytic subunit (NrfA) J Biol Chem 278, 17455–17465...
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Báo cáo khoa học: Identification and characterization of 1-Cys peroxiredoxin from Sulfolobus solfataricus and its involvement in the response to oxidative stress pdf

Báo cáo khoa học: Identification and characterization of 1-Cys peroxiredoxin from Sulfolobus solfataricus and its involvement in the response to oxidative stress pdf

... thioredoxins were found In this study we examined the involvement of the peroxiredoxin Bcp2 in oxidative stress in the hyperthermophilic aerobic archaeon Sulfolobus solfataricus Furthermore, ... clarified in detail and could play a key role in the detoxification processes In this study we examined the role of Bcp2 in order to increase the knowledge of the enzymatic activity involved in the oxidative ... Furthermore, we report the cloning, the expression and the characterization of the recombinant protein rBcp2 in order to shed light on its role in the detoxification process and on its catalytic mechanism...
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Báo cáo Y học: Purification and characterization of novel kininogens from spotted wolffish and Atlantic cod pdf

Báo cáo Y học: Purification and characterization of novel kininogens from spotted wolffish and Atlantic cod pdf

... N-Terminal sequencing of the kininogens was only successful from the 42-kDa band of wolffish kininogen (XLVQPGVLI…, Table 1) The major bands of both kininogens and also the 60-kDa band of cod kininogen ... biantennary and triantennary N-glycans, with extensive sialic acid O-acetylation Also O-glycosidic glycans were recovered from wolffish kininogen The permethylated O-glycan pool was analysed by MALDI-TOF ... N-glycans Ó FEBS 2002 Novel kininogens from cod and wolffish (Eur J Biochem 269) 2643 Fig Alignment of peptides from cod kininogen (COD KIN) and wolf fish kininogen (WF KIN) with heavy chain of human...
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