Chemical and pharmacological studies of ardisia elliptica antiplatelet, anticoagulant activities and multivariate data analysis for drug discovery
Chemical and pharmacological studies of ardisia elliptica antiplatelet, anticoagulant activities and multivariate data analysis for drug discovery
... and pharmacokinetic studies of A elliptica and its isolated bioactive component in rats 137 5.1 Ex vivo and in vivo antiplatelet and anticoagulant activities of A elliptica and β-amyrin in rats ... conventional process of repeated fractionation is a tedious process for the discovery of bioactive components, a platform method for drug discovery from plant extracts using multivariate data analysis (MVDA) ... Validation of GC-MS method for MVDA study 118 4.4.2.2 GC-MS analysis of all extracts and fractions 119 4.4.2.3 PCA and PLS-DA analysis of the extracts and fractions 122 4.4.2.4 Antiplatelet activities...
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Authentication of edible birds nest using advanced analytical techniques and multivariate data analysis
... The content of the thesis has been partly published in: 1) Metabolite profiling of edible bird nest using GCMS and LCMS Chua, Y.G., Bloodworth, B.C., Leong, L.P and Li, F.Y.S, Journal of Mass Spectrometry, ... use of GC/MS and LC/MS 28 Table Examples of food authentication with the different types of multivariate data analysis 39 Table Retention time, linearity, limits of quantitation ... success of authentication For this reason, it is vital to develop accurate and precise analytical methods capable of providing reliable data prior to study of the food item The use of analytical...
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Guide for the Selection of Chemical and Biological Decontamination Equipment for Emergency First Responders ppt
... purpose of this guide is to provide emergency first responders with information that should aid them in the selection and utilization of chemical and/ or biological (CB) decontamination equipment The ... Justice Programs National Institute of Justice Guide for the Selection of Chemical and Biological Decontamination Equipment for Emergency First Responders NIJ Guide 103–00 Volume I Dr Alim A Fatah1 ... recognizing the needs of State and local emergency first responders, the Office of Law Enforcement Standards (OLES) at the National Institute of Standards and Technology (NIST), working with the National...
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Guide for the Selection of Chemical and Biological Decontamination Equipment for Emergency First Responders pdf
... Decontamination Equipment for Emergency First Responders, includes details on the 72 decontamination equipment items that are referenced in Volume I The Guide for the Selection of Chemical and Biological Decontamination ... Volume II of the Guide for the Selection of Chemical and Biological Decontamination Equipment for Emergency First Responders Volume II includes three sections and five appendices Section is the introduction ... recognizing the needs of State and local emergency first responders, the Office of Law Enforcement Standards (OLES) at the National Institute of Standards and Technology (NIST), working with NIJ, the...
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Báo cáo y học: "Construction of a high-resolution genetic linkage map and comparative genome analysis for the reef-building coral Acropora millepora" ppt
... linkage map (L13 and L14) of the reef-building coral A millepora A genetic linkage map (L13 and L14) of the reef-building coral A millepora Female (F) and male (M) maps are shown on the left and ... cM) and represents the first linkage map for a coral, as well as for any non-bilaterian multicellular organism The map will become the foundation for QTL analysis of adaptive traits and population ... of the Bilateria Anthozoan cnidarians such as corals are phylogenetically basal in the phylum Cnidaria, and have proven to be particularly informative for understanding the evolution of metazoan...
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Báo cáo sinh học: " Equivalence of multibreed animal models and hierarchical Bayes analysis for maternally influenced traits" potx
... generalizes to a multibreed population composed of p breeds Hierarchical Bayes analysis for a maternal multibreed animal model Consider now a maternally influenced trait, and assume therefore the covariance ... Equivalence of multibreed animal models and hierarchical Bayes analysis for maternally influenced traits Genetics Selection Evolution 2010 42:20 Submit your next manuscript to BioMed Central and take ... experiment Methods Equivalence of multibreed animal models For the sake of simplicity, assume a two-breed (A and B) composite population with individuals pertaining either to one of the two parental...
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Báo cáo sinh học: "Univariate and multivariate parameter estimates for milk production traits using an animal model. I. Description and results of REML analyses" pptx
... ie an animal model Few (co)variance estimates from AM analyses have been reported; Swalve and Van Vleck (1987) analysed milk yield in lactations 1-3, and Van Vleck and Dong (1988) performed a multivariate ... 5, and subsets (for L L and L ,, 12 respectively), and for 4) into 10 groups of 10 herds For the univariate analyses and the analyses using a repeatability model, the standard errors (SE) of ... coefficient of variation (= a and r the correlation between traits ) //1 ,y x x and y Formula [1] was applied using estimates of the coefficients of variation and estimates of the (co)variances for the...
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Báo cáo sinh học: "Univariate and multivariate parameter estimates for milk production traits using an animal model. II. Efficiency of selection when using simplified covariance structures" docx
... John Wiley and Sons, NY Visscher PM, Thompson R (1992) Univariate and multivariate parameter estimates for milk production traits using an animal model I: Description and results of REML analyses ... moment matrices; A and E are highly correlated and the determinant of A is zero An alternative is to transform A and E into a between and within sire covariance matrix (B and W), assuming these ... choice for the transformation matrix h V is a canonical transformation on M F and P This transformation was l , , 1 calculated (see Hayes and Hill, 1980 ; and lMeycr, 1985, for computations) and...
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System level modeling of endothelial permeability pathway and high throughput data analysis for disease biomarker selection
... research of genomics and genetics, more and more high- throughput data is available. The first section (Section 1.1) of this chapter gives an overview of endothelial permeability and related disease ... mathematical modeling of signaling pathways (Section 1.2) The following sections of this chapter introduce the disease biomarker selection using high throughput data, includes microarray and copy ... effects and the dynamics of multi-mediator regulation The second objective is to design bioinformatics tools for endothelial permeability disease marker discovery using high- throughput dataset A disease...
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Development and interpretation of machine learning models for drug discovery
... concerned with the development and interpretation of machine learning models for drug discovery To this end, it describes the design and application of computational models for specialized use ... focus of this thesis is the development and interpretation of machine learning models for pharmaceutical tasks In drug discovery, project teams usually consist of experts from a variety of disciplines, ... some basic concepts of in silico modeling for drug discovery Concepts Machine learning models for drug discovery mostly try to model the structure-activity relationship of ligand-target interactions...
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MULTIVARIATE DATA ANALYSIS INSENSORY AND CONSUMERSCIENCEGarmt B. Dijksterhuis, Ph.D.ID-DLO, Institute for Animal Science and Health Food Science Department Lely stad The NetherlandsFOOD & NUTRITION PRESS, INC. TRUMBULL, CONNECTICUT 06611 USA.MUL doc
... ID-DLO, Institute for Animal Science and Health Food Science Department Lely stad The Netherlands FOOD & NUTRITION PRESS, INC TRUMBULL, CONNECTICUT 06611 USA Copyright 1997 by FOOD & NUTRITION PRESS, ... MULTIVARIATE DATA ANALYSIS IN SENSORY AND CONSUMER SCIENCE MULTIVARIATE DATA ANALYSIS IN SENSORY AND CONSUMER SCIENCE F N PUBLICATIONS IN FOOD SCIENCE AND NUTRITION P Books MULTIVARIATE DATA ... Science and Health (Lelystad, the Netherlands), leading their sensory laboratory ID-DLO is one of the major research institutes on animal production In their Food Science Department resides the research...
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Tutorial Final and Construction Stage Analysis for a Cable-Stayed Bridge potx
... Stage Analysis Construction stage analysis for a cable-stayed bridge can be classified into forward analysis and backward analysis, based on the analysis sequence Forward analysis reflects the real ... Stage Analysis 42 FINAL AND CONSTRUCTION STAGE ANALYSIS FOR CABLE-STAYED BRIDGES We will generate a construction stage analytical model using the model used in the final stage analysis by saving ... FINAL AND CONSTRUCTION STAGE ANALYSIS FOR CABLE-STAYED BRIDGES A B Fig 41 Input Pretension Loading to Cable Elements 47 FINAL AND CONSTRUCTION STAGE ANALYSIS FOR CABLE-STAYED BRIDGES Define Construction...
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