... MINIREVIEW A study of microRNAs in silico and in vivo: diagnostic and therapeutic applications in cancer Scott A. Waldman1 and Andre Terzic21 Departments of Pharmacology and Experimental Therapeutics ... Hannon GJ et al. (2005) A microRNA poly-cistron as a potential human oncogene. Nature 435,828–833.39 Hayashita Y, Osada H, Tatematsu Y, Yamada H, Yana-gisawa K, Tomida S, Yatabe Y, Kawahara ... of miRNA-based diagnostics and therapeutics into clini-cal practice.AcknowledgementsThe authors are supported by grants from the NIH(SAW, AT), Targeted Diagnostic and Therapeutics,Inc. (SAW), and...