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Báo cáo y học: " The Cell Cycle Ontology: an application ontology for the " pdf

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Báo cáo y học: "Improving benchmarking by using an explicit framework for the development of composite indicators: an example using pediatric quality of care" docx

... Sookanan S: Does pay -for- performance improve the quality of health care?. Ann Intern Med 2006,145:265-272.12. Profit J, Zupancic JA, Gould JB, Petersen LA: Implementing pay -for- performance ... Performance And Equity Oxford: Oxford University Press2003.28. Institute of Medicine: Crossing The Quality Chasm: A New Health System For The 21st Century Washington, DC: National Academy Press ... 13:126-128.42. Saisana M, Saltelli A, Tarantola S: Uncertainty and sensitivity analysistechniques as tools for the quality assessment of composite indicators.Journal of the Royal Statistical Society Series...
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Báo cáo y học: " Emergency medicine in Scandinavia - an outstanding opportunity for research" pdf

... (EM) wasonly something for the rest of the world. Emergencypatients in the Scandinavian countries were still beinghandled by young and poorly trained doctors frommany specialties and no doctor ... doctors reallytook ownership of the ED. However, i n 1999 the Swed-ish Society for Emergency Medicine (SWESEM) wasestablished and things started to change. The DanishSociety for Emergency Medicine ... 2006 and the work to improve the care ofemergency patients began. Finland also has a society butno speciality, whereas in Norway there seem to be noplans to establish EM as a specialty. Sweden...
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Báo cáo y học: "A cell-cycle independent role for p21 in regulating synovial fibroblast migration in rheumatoid arthritis" pps

... cellswere washed with PBS, trypsinized and their number quanti-fied by hemocytometer counts with trypan blue. Analysis wasperformed in triplicate wells and results are expressed as the mean ... phases of the cell cycle is dependent on the activities of cyclin dependent kinases (cdks) bound to theircognate cyclins [1,2]. Another level of cell cycle regulation isaffected by the cdk inhibitors, ... of pannus by migrating into cartilage and bone.We demonstrated previously that expression of the cell cycle inhibitor p21 is significantly reduced in RA synovial lining,particularly in the...
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Báo cáo y học: "Modified cell cycle status in a mouse model of altered neuronal vulnerability (slow Wallerian degeneration; Wlds)" pot

... VCP in the nucleus [63]. Cell cycle pathways and neurodegeneration The hypothesis that Wlds may be modifying neurodegenera-tive pathways in axons and synapses via modulation of the cell cycle ... Pttg1/Ube1-, and VCP-dependentpathways are likely to be required to modulate these cell cycle changes. The data suggest that further investigations into the role of cell cycle and cell stress ... (Figure 1and Table 1). The array identified changes in genes associatedwith many different stages of the cell cycle rather than onespecific stage (Table 1). Interestingly, no cell cycle relatedgenes...
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Báo cáo y học: "Intra-articular hyaluronan (hyaluronic acid) and hylans for the treatment of osteoarthritis: mechanisms of action" pps

... in OA [29,31]. The activity ofmany MMPs increases in OA by either an increase in theirown synthesis, an increased activation by their proen-zymes, or decreased activity of their inhibitors ... NO may be involvedin cartilage catabolism by inhibiting the synthesis of colla-gen and PG, enhancing MMP activity, reducing the synthe-sis of an IL-1 receptor antagonist by chondrocytes, andincreasing ... degradation exceeds synthesis. The balance between synthesis and degradation is affected byage and is regulated by several factors produced by the synovium and chondrocytes, including cytokines, growthfactors,...
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Báo cáo y học: " ncremental cost effectiveness of proton pump inhibitors for the prevention of non-steroidal anti-inflammatory drug ulcers: a pharmacoeconomic analysis linked to a case-control study" potx

... (95% CI of the cost estimate). To show this uncertainty we used the extremeestimates for both the most positive and the most negativeoptions for concomitant PPI therapy and NSAID use. The sec-ond ... contributed significantly to the writing of the paper.MJP, JRBJB and MvdL conceived the study, and participatedin its design and coordination. HEV and MvdL conducted the case-control study. HEV, RMK, ... complications. The group using concomitantPPIs significantly more often used chronic NSAID therapy(more than 3 months continuously), concomitant steroids, hada medical history of anaemia, and of previous...
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Báo cáo y học: "Incremental cost effectiveness of proton pump inhibitors for the prevention of non-steroidal anti-inflammatory drug ulcers: a pharmacoeconomic analysis linked to a case-control study" pptx

... (95% CI of the cost estimate). To show this uncertainty we used the extremeestimates for both the most positive and the most negativeoptions for concomitant PPI therapy and NSAID use. The sec-ond ... complications. The group using concomitantPPIs significantly more often used chronic NSAID therapy(more than 3 months continuously), concomitant steroids, hada medical history of anaemia, and of previous ... contributed significantly to the writing of the paper.MJP, JRBJB and MvdL conceived the study, and participatedin its design and coordination. HEV and MvdL conducted the case-control study. HEV, RMK,...
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Báo cáo y học: "Methods of estimation of mitral valve regurgitation for the cardiac surgeo" pot

... Endorsed by the Society for Cardiovascular Angiography and Inter-ventions Developed in Collaboration With the Society of Cardiovas-cular Anaesthesiologists 1998 Guidelines for the Management ... The advantages and disad-vantages of angiography, Doppler and MRI are presentedin table 2.Advantages and disadvantages of angiography, Doppler and MRIAnother significant component of estimation ... derangements of preloadand afterload (systemic and pulmonary vascular resist-ance for aortic and mitral valve, respectively) which signif-icantly affects the grade of regurgitation, h) the coexistence...
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Báo cáo y học: "P38 MAP kinase inhibitors as potential therapeutics for the treatment of joint degeneration and pain associated with osteoarthritis" ppsx

... com-pany.Authors' contributionsKKB, SAH and EBH performed all of the in vivo studiesand analyzed the data. LH performed all the in vitro stud-ies and analyzed the data. MB designed and ... prepared the formulations for the p38 inhibitors tested in vivo. YOTcontributed to experimental design and data analysis. MJJdesigned in vitro and in vivo studies analysed the data andwrote the manuscript.Acknowledgements The ... in animal models. Therefore, the inhibition ofproinflammatory cytokines may provide an importanttherapeutic approach for the treatment of OA.Clinical trial data on cytokine inhibitors for the...
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Báo cáo y học: " Immature cell populations and an erythropoiesis gene-expression signature in systemic juvenile idiopathic arthritis: implications for pathogenesis" ppt

... the time of the baseline visit (before the initia-tion of DMARD therapy). All further analyses (RNAmicroarray analysis, flow cytometry, and cytokine mea-surement) were pe rformed on these samples. ... performed the statistical analyses and drafted the manuscript. NF carriedout the RNA isolation, some of the flow cytometry, and participated in the statistical analysis. ST, TG, SD, RC, and ... and anti-CD19-APC; (f) anti-CD34-FITC, anti-CD105-PE, anti-CD45-PerCP, and anti-CD33-APC; (g) anti-Lin-FITC,anti-HLA-DR-PE, and anti-CD11c-APC; and (h) anti-Lin-FITC, anti-BDCA4-PE, and anti-CD11c-APC....
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