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Báo cáo sinh học: " Protection against the allergic airway inflammation depends on the modulation of spleen dendritic cell function and induction of regulatory T cells in mice" docx

Báo cáo sinh học:

Báo cáo sinh học: " Protection against the allergic airway inflammation depends on the modulation of spleen dendritic cell function and induction of regulatory T cells in mice" docx

... 10.1186/1479-0556-8-2Cite this article as: Wang et al., Protection against the allergic airway inflam-mation depends on the modulation of spleen dendritic cell function and induction of regulatory T cells in mice ... and mature DCs, resulting in tolerogenic interaction with T cells in SIT. We found that the combination of DNA vac-cination with Fc and OVA had better effects onOVA-induced alterations in the ... DCs and Foxp3+Tregs prevents the generation and activation of Th2 effector cells as anovel pathway of regulation of type 2 immunity in asthma.Competing interests The authors declare that they...
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báo cáo sinh học:" Using nurses to identify HAART eligible patients in the Republic of Mozambique: results of a time series analysis" potx

... differ-ential implementation of the intervention itself. The results from the first outcome (the proportion of visitswith HAART-eligible patients) suggest that the implemen-tation of the intervention ... remained significantly associatedwith time to starting HAART. There was no significantinteraction between the study site and the study month, orbetween the study site and the introduction of the ... initiating treatment. Future studies of this typeshould be initiated only after the rate of starting patients on HAART is stable to more clearly differentiate the impact of the intervention...
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báo cáo sinh học:" Field Epidemiology Training Programmes in Africa - Where are the Graduates?" pptx

... ensured that training remains rele-vant to the needs of the ministry and the country’s healthsector; hence graduates get placements easily within the country of training.b) The second is on the ... oftenfrustrated by their inability to work in health systemsthat they did not train in and eventually join the braindrain.We therefore recommend that countries, governments and training institutions ... publications and job promotions since graduation.Conflict of interests The authors declare that they have no competing interests.Authors’ contributionsDM: Contributed to study conception and design,...
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Báo cáo sinh học: "Future perspectives in melanoma research. Meeting report from the "Melanoma Research: a bridge " doc

... targetfor the treatment of solid malignancies. Furthermore, itseems that tumor-initiating cells might be resistant tomany conventional cancer therapies, which might explain the limitations of these ... targeted with inhibitors such as nilotinib and dasatinib. These are currently be ing studied in the phase III TEAM trial (nilotinib against dacarbazine in the treatment of metastatic and/ or inoperable ... predictive markers for the few existing therapeuticagents. Adjuvant therapy of melanoma is the settingthat may lend itself to the improvement of treatmentgiven the series of studies of the ECOG...
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Báo cáo sinh học: " A conditional-lethal vaccinia virus mutant demonstrates that the I7L gene product is required for virion morphogenesis" pptx

... while in the absence of TET the production of infectious virus was much lowerindicating that the presence of the TET operator did nothave an effect on the growth kinetics of the induciblemutant ... dueto gene copy overwhelming the amount of TetR beingexpressed by the TREx-293 cell line.To test whether the insertion of the TET operator justupstream of the I7L ORF had an effect on the ... virus.To demonstrate that the replication defect of the vtetOI7Lmutant virus in the absence of TET was due to the I7L genewe tested whether viral replication could be rescued by the introduction...
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Báo cáo sinh học: "Process rather than pattern: finding pine needles in the coevolutionary haystack" doc

... great as to lead to shiftsbetween parasitism and mutualism, but outcomes aredependent on the interactions of the adaptations of bothpartners with the environment that they find themselves in. Hence, ... observational rather than experimental, so that process and pattern cannot be disentangled. The area of the theoryto which this limitation applies most is the demonstration of selection mosaics, and ... dependent notonly on the adaptations of their partner, but also on the environment in which the interaction occurs. This is perhapsmost easily seen in what have been termed ‘conditionalmutualisms’...
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Báo cáo sinh học: "Beyond toxicity: aryl hydrocarbon receptor-mediated functions in the immune system" docx

... the cytokines act on other immune cells, activating them in turn. The four known subsets of CD4 T cells are T H1 cells, which induce in ammatory responses that protect the tissues; T H2 cells, ... cells) . CD4 T cells are further subdivided into four clearly defined subsets with distinct functions that are mediated by the distinct cytokines they secrete and that act on other immune cells (Figure ... dioxin-mediated toxicity may, in fact, reflect disruption of the endogenous function of this receptor by inducing sustained and inappropriate AhR signaling due to the stability of the toxin, and thus...
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Báo cáo sinh học: " Chromatin ‘programming’ by sequence - is there more to the nucleosome code than %GC" pot

... effect’ - in other words, outlying points drive correla tions (even if the bulk of the data are uncorrelated), and in the case of chromatin structure these outlying points correspond to the ... scored for their match to this distribution. Predictions of this model correlated very well (0.89) with in vitro reconstitution data, suggesting that the majority of the affinity of a given ... correlation coeffi-cients are being used as the summary statistic.Trimming the fat from computational models In addition to establishing that intrinsic ‘programming’ of chromatin architecture...
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Báo cáo sinh học: "Inference for threshold models with variance components from the generalized linear mixed model perspective" ppt

... neither in the generation of the data nor in the model fitted. The negative value for this configuration indicatesthat, although the bias seems fairly independent of the ... presented in Harville and Mee (1984), including estima-tion of variance components. Their updates of the components of variance are akinto those of the estimation maximization ... on sire evaluation Thompson (1979) already pointed out the potentialinterest for binomial data in modifying the generalized linear model (GLM) esti-mating equations to...
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Báo cáo y học: " Protection against H1N1 influenza challenge by a DNA vaccine expressing H3/H1 subtype hemagglutinin combined with MHC class IIrestricted epitopes" ppsx

... immunogenicity, rapid prepara -tion, protection against rapid virus mutation and long-term protection against multiple subtypes of influenza,especially against potential influenza pandemic strains. The ... they determine the specificity of antibodies. B cells can capture antigens through the BCR and function a sAPC to activate Th cells. Activated Th cells can alsoactivate B cells in turn to produce ... digested intolinear epitopes and then later associated with MHC IImolecules to be presented on the surface of the APC.Th cells and APC recognition between cells and signaltransduction and the...
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