... more effec-tive. In a prospective, randomized, double-blind, parallel-group, dose-ranging study of 48 weeks, 60 women received 16, 32, or 48 U BTX-A Advanced Cosmetic Use of Botulinum Toxin Type ... lasting) injectable available. In soft-tissue augmentation,silicone is injected using microdroplet technique into the subdermal spacevia a 30-gauge needle. After being injected, the silicone induces ... more effective, longer-lasting results,especially in the mid- and lower face. Fagien and Brandt (25) found thatBTX-A in patients undergoing soft-tissue augmentation in certain facialareas, (i.e.,...