... degradation and synthesis products by means of assays for type I and II cleavage by collagenases (Col2:3/4Cshort or C1,2C), type II cleavage onlywith Col2:3/4Clongmono (C2C), type II synthesis ... pentameric protein of the thrombospondin family which can bind type I, II, and IX colla-gens [36]. It is synthesized by chondrocytes, synovial cells, and other cells of the skeleton. Its synthesis is ... lateral, and skylineviews) and if on any of these views they had a definite osteo-phyte in the symptomatic knee (either tibiofemoral or patel-lofemoral), they were eligible for the study. In...