Báo cáo y học: " A method for the generation of standardized qualitative dynamical systems of regulatory networks" doc

... of creating the dynamical system in a fully automated way.Nonetheless, after the initial construction and analysis of the resulting system, the modeler may modify the values of the parameters so as to ... logical analysis to find all the steadystates of the system [15]. Generalized logical analysisallows us to find all the steady states of a discrete dynam-ical system by evaluating the functionality ... this paper to present a detailedmathematical analysis of the dynamical system describedby Equation 3. Instead, we present a framework that canhelp to speed up the analysis of the qualitative...

Báo cáo y học: " A method for studying decision-making by guideline development groups" potx

... from a broad thematic analysis of a subset of data, to extract data excerpts warranting fur-ther analysis.Identifying areas of interestOne key assumption made by the research team, on the basis ... identify andtrack the development of the theme through the course of the GDG. In this way, themes of apparent importance to the process of decision-making are the focus of analysis,Implementation ... Similarly, a study of two independ-ent expert panels formulating appropriateness criteria for investigation of patients with angina found that, given the same evidence summary and using a formal...

Báo cáo y học: " Concomitant homozygosity for the prothrombin gene variant with mild deficiency of antithrombin III in a patient with multiple hepatic infarctions: a case report" pdf

... hepatic infarction is rare because of the richly anasta-mosing collateral arterial supply, and the dual blood sup-ply from the portal vein and hepatic artery. In this case,there was portal hypertension ... life-long anticoagulation.ConsentWritten informed consent was obtained from the patient for publication of this case report and accompanyingimages. A copy of the written consent is available for review ... hypertension as evidenced by splenom-egaly, thrombocytopenia, and peri-gastric venous varices. The portal vein may have thrombosed and recanalised,similar to the patient's leg DVT and the hepatic...

Báo cáo y học: "A role for the histone deacetylase HDAC4 in the life-cycle of HIV-1-based vectors" ppsx

... 5′-CCTGCGTCGAGA GAGCTC-3′. To quantitate the viralamplicon, a TaqMan dual 5′-6-carboxyfluorescein-and3′-6-carboxytetramethylrhodamimine-labeled probe wasused: 5′ -(FAM)-CAGTGGCGCCCGAACAGGGA-(TAMRA)-3′ ... proteins that are homologous to the yeast deacety-lase Sir 2 [14,15]. Finally, the Class IV contains enzymeswhicharerelatedtothoseofClassIandClassII,butasequence analysis shows they form a distinct ... conclude that HDAC4 defi-ciency does not appear to significantly affect the effi-ciency of integration. Similarly, it appears that HDAC4is not n ecessary for the last step of the integration pro-cess,...

Báo cáo sinh học: " A method for the dynamic management of genetic variability in dairy cattle" pot

... up habits already well-known as harmful for ge-netic gains and additionally detrimental for a good management of geneticvariability.Because of the future challenging situation for dairy cattle ... drift.Second, as a major constraint, the average EBV of the future individuals for an overall combination of many traits of economical importance, was setto a desired value. This operational choice was ... let A = A 00 A 01 A 10 A 11then θ = A 01˜x1. Because all the terms of A 01and ˜x1are positive, all of θ arepositive.Theory [24] has shown that, if an inequality constraint (feasibility)...

Báo cáo y học: "A method for high-throughput gene expression signature analysis" ppt

... documentcontaining raw LMF data used to assess the stability of the LMF method (in the tab-delimited .txt file format; Additionaldata file 7); and a document containing raw LMF data from the analysis of the ... fileAdditional data file 6A document containing raw LMF data used to assess the stability of the LMF methodA document containing raw LMF data used to assess the stability of the LMF methodClick here for ... for fileAdditional data file 7A document containing raw LMF data used to assess the stability of the LMF methodA document containing raw LMF data used to assess the stability of the LMF methodClick...

Báo cáo khoa học: A strategy for the generation of speciﬁc human antibodies by directed evolution and phage display An example of a single-chain antibody fragment that neutralizes a major component of scorpion venom docx

... CCACCAGAACCTCCGCCTCCTGATCCGCCACCTCCTGAGGAGACGGTGACCAGGGTGCCJH3.link CCACCAGAACCTCCGCCTCCTGATCCGCCACCTCCTGAAGAGACGGTGACCATTGTCCCJH4-5.link CCACCAGAACCTCCGCCTCCTGATCCGCCACCTCCTGAGGAGACGGTGACCAGGGTTCCJH6.link ... GGCGGATCAGGAGGCGGAGGTTCTGGTGGAGGTGGGAGTGAAATTGTGTTGACGCAGTCTCCVK4.link GGCGGATCAGGAGGCGGAGGTTCTGGTGGAGGTGGGAGTGACATCGTGATGACCCAGTCTCCVK5.link GGCGGATCAGGAGGCGGAGGTTCTGGTGGAGGTGGGAGTGAAACGACACTCACGCAGTCTCCVK6.link ... GGCGGATCAGGAGGCGGAGGTTCTGGTGGAGGTGGGAGTCACGTTATACTGACTCAACCGCCVL5.link GGCGGATCAGGAGGCGGAGGTTCTGGTGGAGGTGGGAGTCAGGCTGTGCTCACTCAGCCGTCVL6.link GGCGGATCAGGAGGCGGAGGTTCTGGTGGAGGTGGGAGTAATTTTATGCTGACTCAGCCCCAJH1-2.link...

Báo cáo toán học: "A formula for the bivariate map asymptotics constants in terms of the univariate map asymptotics constants" pps

... constants tgand pgalso appear.In 1993, the author [18] showed that many natural families of maps satisfy asymptoticformulas similar to (1) in which the same constants tgand pgappear in the coefficients.So ... variety of mapson surfaces and the parameters tg(r) and pg(r) arise in the corresponding bivariate asymp-totics for maps as well as embeddable graphs. The original recursions for these parametersmake ... implies that the coefficients in the asymptotic formulas for many families of mapsand graphs can be computed efficiently.We also mention that some results are known for computing the exact values of Tg(n),...

Báo cáo khoa học:" A role for the JAK-STAT1 pathway in blocking replication of HSV-1 in dendritic cells and macrophages" docx

... 5'-CTGG-TACGCGATCAGAAAGC-3'; and probe, 5'-FAM-CAGCCGCAGTACTACC-3' – Amplicon length = 72 bp. Asan internal control, a set of GAPDH primers from AppliedBiosystems (ASSAY ... 5'-CAGTAGCGTGGGCATTT-TCTG-3'; reverse primer, 5'-CCTCGCCGGCAACAAAA-3';and probe, 5'-FAM-CTCCAGGCGGACTTC-3' – Ampliconlength = 59 bp; and 4) gB: forward primer, 5'-AACGCGACGCACATCAAG-3', ... using a plaque assay as described in Materials and Methods. At allMOIs, replication of HSV-1 in DCs was dramatically lowerthan that seen in RS cells (Fig. 1A) . At 48 hrs post-infec-tion, the amount...

Báo cáo khoa học: " A role for the JAK-STAT1 pathway in blocking replication of HSV-1 in dendritic cells and macrophages" pps

... primer, 5'-AACGCGACGCACATCAAG-3', reverse primer, 5'-CTGG-TACGCGATCAGAAAGC-3'; and probe, 5'-FAM-CAGCCGCAGTACTACC-3' – Amplicon length = 72 bp. Asan internal control, ... of McKrae. At the indicated times post infection the cells were harvested and reacted with Annexin-V or 7-ADD dye to analyze apoptosis and cell death respectively and FACS analysis was performed ... determined the amount of gB DNA as a measure of the relative amount of viral genomic DNA(Fig. 2B). Infected STAT1-/- DCs had significantly more gBDNA than the STAT+/+ parental 129SVE DCs...

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