... role of the N-terminal region of the myosin head in the communicationbetween the motor domain and regulatory domain can alsobe proposed. In the crystal structures of the class II myosins, the N-terminal ... compared the thermal unfolding of S1 specieswith the heavy chain cleaved by trypsin at specific, well-defined sites.Thermal unfolding of S1 cleaved by trypsin in the absence of nucleotides First, the ... changes expressed in asignificant increase of its thermal stability. Furthermore, in the presence of F-actin, another myosin fragment with verylow thermal stability, MyoIE700 (i.e. the isolated...