Báo cáo y học: "Mechanisms of leukocyte distribution during sepsis: an experimental study on the interdependence of cell activation, shear stress and endothelial injury" potx
Báo cáo y học: "Mechanisms of leukocyte distribution during sepsis: an experimental study on the interdependence of cell activation, shear stress and endothelial injury" potx
... Mechanisms of leukocyte distribution during sepsis: an experimental study on the interdependence of cell activation, shear stress and endothelial injury. Critical Care 2010 14:R201.Submit your ... 14:R201http://ccforum.com/content/14/6/R201Page 10 of 13RESEARC H Open AccessMechanisms of leukocyte distribution during sepsis: an experimental study on the interdependence of cell activation, shear stress and endothelial ... infection.Since the effects of shear stress, tissue hypoxia, cell activation and cell injury are hardly distinguishable fromFigure 5 Effects of shear stress and different conditions of activation on rolling...
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Báo cáo y học: "Cerebral microcirculation is impaired during sepsis: an experimental study" pdf
... Resources and National Research Council.Guide for the Care and Use of Laboratory Animals Washington: NationalAcademy Press 1996.31. Dubois EF: The estimation of the surface area of the body. BasalMetabolism ... perdynamic phase) and 12 hours(corresponding to the onset of organ dysfunctions). Inview of the fact that some animals may die earlier than18 hours after feces injection and that global hemody-nam ... examination of brain par-enchyma. Finally, we could not simultaneously investi-gate other microcirculations; because of the positioning of the head of the animal (the head was kept in the same...
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Tài liệu Báo cáo Y học: Granule-bound starch synthase I A major enzyme involved in the biogenesis of B-crystallites in starch granules ppt
... course of storage starch synthesis show that amylopectin and amylosesynthesis are partly disconnected and that amylose synthesispersists when the rate of polysaccharide and amylopectinsynthesis ... amylopectin into the formation of B-type crystals. Another mechanism would consist of crystallization of newly synthesized molecules into B-typematerial. This could involve only de novo synthesizedproducts ... for amylopectin synthesis. However between 12 and 58 h the rate of amylose synthesis becomes significant.After an additional 63 h, the rate of polysaccharidesynthesis decreases further and the...
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Báo cáo y học: "Most nuclear systemic autoantigens are extremely disordered proteins: implications for the etiology of systemic autoimmunity" pps
... with the T cell antigen prediction from Fig. 4,one can see that the strongly disordered regions of the PONDR® plots correspond to regions of the T cell epitope plotin which only a very few ... predictions. The first of these is that only T cells with a very limited range of specifici-ties are needed to activate secondary B cells carrying a widerange of specificities. The study of T -cell ... because of their conformational flexibility, masking by nucleic acids and other proteins and their proteolytic lability, make poor anti-gens. Thus, both intuitions about what makes a good antigenand...
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Báo cáo y học: "THR0921, a novel peroxisome proliferator-activated receptor gamma agonist, reduces the severity of collagen-induced arthritis" pps
... synovium; 1, synovial membrane hypertrophy and cell infiltrates; 2, pannus and cartilage erosions, 3, majorerosions of cartilage and subchondral bone; and 4, loss of joint integrity and ankylosis. ... characterized by infiltration of leukocytes and erosion of cartilage and bone. Recent studieshave indicated that many of the cells involved with RA, namelymononuclear leukocytes [29], articular ... inflam-mation and redness; 2, severe erythema and swelling affecting the entire paw, with inhibition of use; and 3, deformed paw orjoint, with ankylosis, joint rigidity, and loss of function. The totalscore...
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Báo cáo y học: "Indoleamine 2,3-dioxygenase-expressing dendritic cells are involved in the generation of CD4+CD25+ regulatory T cells in Peyer''''s patches in an orally tolerized, collagen-induced arthritis mouse model" ppt
... to the foot or ankle, 2 =slight edema and erythema from the ankle to the tarsal bone,3 = moderate edema and erythema from the ankle to the tarsalbone, and 4 = edema and erythema from the ankle ... proliferation [12]. The mechanismsunderlying the suppression by DCs of the expansion and dif-ferentiation of effector T cells and promotion of T -cell toleranceremain elusive.One regulatory mechanism ... advised on the study. H-SP, Y- OJ, and S-HC performed the experimen-tal work H-YK is the head of the laboratory, supervised the experimental work, and advised on the study. S-HP, and J-KMare the...
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Báo cáo y học: "Genomic transcriptional profiling identifies a candidate blood biomarker signature for the diagnosis of septicemic melioidosis" ppsx
... differentially expressed, unsupervised analysesalso revealed heterogeneity among the sepsis signature.Canonical pathway and gene network analysis of the 37 classifiersFigure 7Canonical pathway and ... indicated by a spot, with the intensity of the spot representing the proportion of significantly differentially expressed transcripts for each one of the transcriptional modules. The color of the spot ... which can delay the initiation of appropriate therapy [1,10-12]. Antibody detec-tion by indirect hemagglutination assay is faster than culturebut lacks sensitivity and specificity, especially when...
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Báo cáo y học: " Non infective severe aortic paravalvular leakage 7 years after surgery: the role of suture technique" pot
... and reproduction in any medium, provided the ori ginal work is properly cit ed.position and function of the prosthesis The postopera-tive course was uneventful and the patient was shortlydischarged.DiscussionAVR ... the patients and may reduce also the occur-rence of endocarditis after prosthetic valve imp lantation. An additional advantage of the continuous suture tech-niquemaybethepresenceoflessthrombogenicmate-rial ... [3]. On the other hand Laks et coworkers [4] hadincidence of PVL of only 2.3% and Qicai [5] surprisingly0%. The advantages of the semicontinuous suture t ech-nique may consist in a shorter...
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Báo cáo y học: "Is research working for you? validating a tool to examine the capacity of health organizations to use research" doc
... an employee of the Canadian Health ServicesResearch Foundation at the time of manuscript develop-ment.Authors' contributionsAK participated in the design and analysis of the study, and ... led the development of the manuscript. NE partici-pated in the design and analysis of the study, and contrib-uted to the manuscript. NH participated in datacollection, and helped to draft the ... individually completed the tool (sometimes in advance of the meeting) and then theydiscussed the items and their rankings, and in most casesderived a group consensus ranking on items. The researchteam...
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Báo cáo y học: " Treatment with a neutralizing anti-murine interleukin-17 antibody after the onset of coxsackievirus b3-induced viral myocarditis reduces myocardium inflammation" pdf
... coordinated the study, performed the statistical analysis and interpretation of data, prepared the draft of manuscript and reviewed it. WW conceived of the study and designed it,coordinated the study and ... anti-murineinterleukin-17 antibody after the onset of coxsackievirus b3-induced viral myocarditisreduces myocardium inflammationYang Fan, Wu Weifeng1,2*, Yan Yuluan, Kong Qing, Pang Yu, Huang YanlanAbstractBackground: ... deficiency of IL-17 and provide efficient effector cells recruitment,secondary loss of response to IL-17 inhibition mayresult from the induction of other pathways and repla-cing the initial...
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