Báo cáo y học: " The value of a risk model for early-onset candidemia" ppt

... patients and accounts for an increased length of stay and significant morbidity and mortality, ranging from25 to 58% [2-4]. Many of these data have been evaluated inCommentary The value of a ... withadditional variables) for sensitivity analysis. The risk scorewas then validated using the 2006/2007 year cohort for a total of 24,685 bloodstream infections. The rate of candidemia was 1.2% ... factors for the initiation of empiric antifungaltherapy therefore provides the best method for early appropriatetherapy. Shorr and colleagues have devised a risk score to identifypatients with early-onset...

Báo cáo khoa học: "The Design of a Computer Language for Linguistic Information" ppt

... associated iexical entry. Other arcs may encode information about the syntactic features, translation, or syntactic subcategorization of the entry. But only the label cat has ally special sig- ... that the agr feature of the DAG associated with the VP be the same as (unified with) the agr of the V. Thus, the VP's agr feature will have as its value the same node as the V's agr, ... label /value pairs, where the values are themselves DAGs (either atomic or complex). Two labels can have the same value thus the use of the term graph rather than tree. DAGs are notated either by...

Báo cáo y học: "The value of correlation of serum 20S proteasome concentration and percentage of lymphocytic apoptosis in critically ill patients: a prospective observational study" pps

... studyAyman A Yousef1*, Ghada A Suliman2, Maaly M Mabrouk2AbstractIntroduction: Sepsis in critically ill patients is almost associated with bad prognosis and its early detection mayimprove ... is therefore typically usedwithavitaldyesuchas7-AADtoidentifytheearlyapoptotic cells (phycoerythrin 7-AAD-negative/FITCannexin V-positive) and to d ifferentiate the late apop to-tic or dead ... 0.001) (Table 2 and Figure 1).Ther e was a significant variation of the median valuesamong the studied groups regarding the percentage of apoptotic lymphocytes: the median value for the sepsisgroup...

Báo cáo y học: "The Impact of a Nationwide Antibiotic Restriction Program on Antibiotic Usage and Resistance against Nosocomial Pathogens in Turkey"

... Hospital setting and antibiotic policy: NARP was initiated in Turkey in February 2003 by a central regulation of Ministry of Health and was announced nation-wide via official newspaper of the ... for non-parametric correlations. A P value of less than 0.05 was regarded as significant. Software package STATA 9.0 (USA) was used for the analysis. Results In total, 14,233 microorganisms ... The Impact of a Nationwide Antibiotic Restriction Program on Antibiotic Usage and Resistance against Nosocomial Pathogens in Turkey Adalet Altunsoy1, Cenk Aypak2, Alpay Azap1, Önder...

Báo cáo y học: " the Value of Serum Biomarkers (Bc1, Bc2, Bc3) in the Diagnosis of Early Breast Cancer"

... Statistical Analysis Spectra data were transferred to a data processor and software capable of analyzing univariate statisti-cal analysis (ProteinChip Data Manager Software). Mass calibrations ... profiles. Another factor may be the differences in sta-tistical analyses. Direct analyses on linear data were used in the present study and the study by Mathelin et al. (27). Li et al., on the other ... instead of target-ing a specific anomaly that may occur in a small sub-group of patients. Both genomic and proteomic ap-proaches accumulate multidimensional data which may be analyzed by multivariate...

Báo cáo Y học: The presence of a helix breaker in the hydrophobic core of signal sequences of secretory proteins prevents recognition by the signal-recognition particle in Escherichia coli doc

... molecules may still rely on the SecB pathway,because of overloading of the SRP pathway. The re-routing of (G-10L)prePhoE to the Sec translocon via the SRPinstead of the SecB pathway could be explained ... a known substrate of the SRP pathway, FtsQ was used as a model. This class IImembrane protein, with a short N-terminal cytoplasmic tail[39], was synthesized as a slightly longer nascent chain ... dependency of the precursor on SecA and SecY,whereas its SecB dependency is reduced.Afﬁnity of mutant prePhoE nascent chains for P48As the SecB dependency of the translocation of the mutantprePhoE...

Báo cáo Y học: The reactivity of a-hydroxyhaem and verdohaem bound to haem oxygenase-1 to dioxygen and sodium dithionite pdf

... as well as according to the procedures of Migita. We ﬁnd that complex formation of a- hydroxyhaem with haem oxygenase may be small and a substantial amount of free a- hydroxyhaem may remain,depending ... can contain a substantial amount of free a- hydroxyhaem and this can lead to an incorrect interpret-ation of the nature of the enzyme-assisted conversion of a- hydroxyhaem to verdohaem. The reaction ... to the enzyme is ﬁrst hydroxylatedat the a- meso-carbon, yielding a- hydroxyhaem. The secondstep is the conversion of a- hydroxyhaem to verdohaemwith the concomitant release of the a- meso-carbon...

Báo cáo y học: "The value of animal models in predicting genetic susceptibility to complex diseases such as rheumatoid arthritis" ppsx

... for the NOX-complex in autoimmunity.Arthritis Res Ther 2007, 9:R98.83. Sakaguchi N, Takahashi T, Hata H, Nomura T, Tagami T, YamazakiS, Sakihama T, Matsutani T, Negishi I, Nakatsuru S, Sakaguchi ... to the joints,and the disease exhibits many of the characteristics of humanRA. Autoantibodies play a pathogenic role in this model, because arthritis can be transferred to a wide range of recipients ... be regarded ascompeting options, but rather as complementary strategiesthat, together, could provide a true understanding of the genes and pathways that affect human diseases. They mayalso...

Báo cáo y học: "The value of sensitive imaging modalities in rheumatoid arthritis pdf

... addressing the use of conventional grey-scale (B-mode) ultrasonography (US) in the evaluation of RA synovial inflammation and joint damage indicate thatclinical joint examination and CR are comparatively ... gold-standardmethodology for assessment of joint damage in RA? The assessment of structural damage by CR relatespoorly to function in early RA, although in disease of 5 years’ duration or longer there ... particularly of the second andthird metacarpophalangeal joints and the fifth meta-tarsophalangeal joint, may be very valuable to confirm the presence of erosive disease.While high-frequency (grey-scale)...

Báo cáo y học: "The validity of a rheumatoid arthritis medical records-based index of severity compared with the DAS28" docx

... characteristics and the RARBIS scorePatient characteristics of the study cohort are summarized inTable 2. The mean age of patients was 59 years with the majority less than 65 years. Most of the ... priorsurgical history, radiologic and laboratory findings, clinical andfunctional status, and extra-articular manifestations. The Spearman correlation between the RARBIS and the DAS28was assessed in the ... patients were female(81%) with mean disease duration of 16 years. The mean value of the DAS28 was 4.2 (standard deviation [SD] 1.6) atbaseline. The mean total RARBIS score calculated for allpatients...

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