... Post*†*Hospital for Sick Children Research Institute, Toronto, and †University of Toronto, Toronto, CanadaAbstractThe hedgehog signalling pathway has been implicated in many different processes in fly ... Sekine K, Ohuchi H, Fujiwara M, Yamasaki M, Yoshizawa T, Sato T, ••Yagishita N, Matsui D, Koga Y, Itoh N, Kato S: Fgf10 is essential for limb and lung formation. Nat Genet 1999, 21:138–141.Mice ... development, the mammalian lung establishes a large diffusible interface with the circulation to facilitate res-piratory gas exchange at term. In the human, the appear-ance of a midventral groove in...