... values. The development of sepsis from a localized infection isa dynamic continuum and in the majority a sequelae of CAP [54]. The severity of a disease determines the con-sumption of costly and ... ampli-fied cryptate emission (TRACE) technology assay (PCTKryptor®, B.R.A.H.M.S. AG, Hennigsdorf, Germany). The assay has a detection limit of 0.02 μg/L and functionalassay sensitivity of 0.06 ... standardized care of patients as defined previously [34]. Thereby, LRTI wasdefined by the presence of at least one respiratory symp-tom (cough, sputum production, dyspnea, tachypnea,pleuritic...