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Báo cáo y học: "In silico evidence for the species-specific conservation of mosquito retroposons: implications as a molecular biomarker" ppt

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Báo cáo y học: "In silico evidence for the species-specific conservation of mosquito retroposons: implications as a molecular biomarker" ppt

... Kampala, Uganda and 5Dept of Immunology and Microbiology, Kampala International University, Western Campus, PO Box 71, Ishaka, UgandaEmail: Wilson Byarugaba - wbyarugaba@yahoo.co.uk; Henry ... was done using the three RST (AJ970181,AJ970201 and AJ970301) as queries against the 1,778organismal and the human genome databases by way of BLAST-N calibrated at Expect (E) = 10, Filtration ... participated in data analysis and writing the final manuscript. All authors read and approved the final manuscript.Additional materialAcknowledgementsWe thank the editorial team at BMC Theor Biol...
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Báo cáo y học: "In vitro model for the analysis of synovial fibroblast-mediated degradation of intact cartilage" pptx

... histologically and two were proc-essed for mRNA analysis of the SFB layer and cartilage. For each experimental parameter, patient SFB were analysed sep-arately for each donor.After 14 days of in ... productHuman/bovine Aldolase A 5'-TCATCCTCTTCCATGAGACACTCTA-3'5'ATTCTGCTGGCAGATACTGGCATAA-3'[GenBank: NM_000034]58°C 88°CHuman MMP-1 5'-GACCTGGAGGAAATCTTGC-3'5'-GTTAGCTTACTGTCACACGC-3'[GenBank: ... fibroblasts to degrade intact cartilage matrixby disturbing the homeostasis of cartilage via the production of catabolic enzymes/pro-inflammatory cytokines and suppression of anabolic matrix synthesis...
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Báo cáo y học: " In silico modeling indicates the development of HIV-1 resistance to multiple shRNA gene therapy differs to standard antiretroviral therapy" docx

... efficacy The containment of resistance to the gene therapy isonly one measure of total efficacy. Further measures of therapy effectiveness can be obtained by the e xtent of viral suppression as measured ... targets as they are likely to be critical for viral fit-ness. Further, the selection of highly conserved sitesensures the therapy matches the maximum number of viral variants. Mathematical analysis ... granulocytes andmacrophages [17]. As they are stem cells, they are ca p-able of providing a continual source of progeny cellscontaining the therapeutic sequence.Mathematical modelling of gene therapy...
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Báo cáo y học: "Phenylephrine versus norepinephrine for initial hemodynamic support of patients with septic shock: a randomized, controlled tria" doc

... Data from right heart catheterization, a thermodye dilution catheter, gastric tonometry, acid-basehomeostasis, as well as creatinine clearance and cardiactroponin were obtained at baseline and ... as measuredby the gradient between gastric mucosal and arterial pCO2, itdecreased hepatosplanchnic perfusion as indicated by a decrease in the PDR and CBI associated with a slight increasein ... Lifesciences) and a radialartery catheter (20 G; Arrow International Inc, Reading, PA,USA). The MAP, right atrial pressure, mean pulmonary arterialpressure, and PAOP were measured at end expiration. The heart...
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Báo cáo y học: "Quantitative ultrasound can assess the regeneration process of tissue-engineered cartilage using a complex between adherent bone marrow cells and a three-dimensional scaffold" docx

... developed a new ultrasonic evaluation system for articular cartilage and showed that this system can quanti-tatively evaluate cartilage degeneration clinically [6,7]. The analysis system is based ... two along a sagittal plane using a diamond band saw(EXAKT BS300CL; Meiwa, Tokyo, Japan). One part was used for histological analysis and the other for biochemical analysis.Histological samples ... Masao Sato3 and Ken Ikeuchi41Department of Orthopaedic Surgery, Nara Medical University, Nara, Japan2National Institute of Advanced Industrial Science and Technology, Amagasaki Site, Hyogo,...
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Báo cáo y học: "Proteome-wide evidence for enhanced positive Darwinian selection within intrinsically disordered regions in proteins" pdf

... was assumed and anapproximate z-value was calculated as above. In caseswhere the number of informative windows was fewerthan 30 but more than 5, significance was assessed byconsulting a table ... molecular basis of human disease as well as the mechanisms underlying pharmaceuticaltherapy [10].Evolvability is often described as an organism’s capacityto generate heritab le phenotypic variation ... study as well as interpretation of results and preparation of the manuscript. AW was involved in the conception and planning of the study as well as interpretation of results and writing the manuscript....
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Báo cáo y học: " No genetic evidence for involvement of Deltaretroviruses in adult patients with precursor and mature T-cell neoplasms" doc

... FASTA fileformat, and aligned using the ClustalX software [35].Phylogenetic analysis The PHYLIP program package [36], version 3.65 for MacOS X, with the program modules dnacomp and draw-gram ... etiology of many human malignant T-cell and T-/NK-cell disorders is still not well understood.On the other hand a great deal of knowledge has beengained in the last years on the molecular biology ... designed and performed the laboratory work, particu-larly the PCR, did the alignments and phylogenetic analy-sis and wrote the paper. SS and ET performedimmunophenotyping of samples. MH characterized...
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Báo cáo y học: " In silico analysis of chimeric espA, eae and tir fragments of Escherichia coli O157:H7 for oral immunogenic applications" doc

... 0GTAAAA 1 0GTAAGT 2 0GTACGT 0 0Poly A AATAAA 1 0AATGAA 0 0AATGGA 0 0TATAAA 2 0AATAAT 3 0AAAAAAA 1 0Poly TTTTTTT 1 0Destabilizing elementATTTA 3 0 ... attachment and effacement. (A) Evaluation of model stability based on a Ramachandran plot and (B) energy minimizationFigure 5 (A) Evaluation of model stability based on a Ramachandran plot and (B) ... gene was constructed based on the codon usage of highly expressed nuclear-encoded genes of tobacco (Nico-tiana tobaccum L.) as a model, and canola (Brassica napusL.) as the final target plant...
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Báo cáo y học: " Developing quality indicators for the care of HIVinfected pregnant women in the Dutch Caribbea" pot

... feasible if the data necessaryto score the indicator could be abstracted from the available data for > 70% of the cases [19].Sample size of the indicator was related to the number of patients ... unknown gesta-tion d uration, or deliveries abroad.Feasibility of th e indicator was defined as the availability of admin-istrative data required to evaluate the indicator. An indi-cator was considered ... DutchCaribbean consists of Aruba and the Netherlands Antil-les (Saba, St Eustatia, Bonaire, St Maarten and Curaçao)and has an estimated prevalence of HIV-1-infection of 0.61%-1.05% in the adult...
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Báo cáo y học: " In-Silico docking of HIV-1 integrase inhibitors reveals a novel drug type acting on an enzyme/DNA reaction intermediate" pdf

... and Xa. Bioorg Med Chem Lett 2004,21:5263-5267.34. Sato M, Motomura T, Aramaki H, Matsuda T, Yamashita M, Ito Y, Kawakami H, Matsuzaki Y, Watanabe W, Yamataka K, Ikeda S,Kodama E, Matsuoka M, ... display sim-ilar 3D folding of the catalytic domain and a conservedcatalytic triad of metal-coordinating carboxylates. INcatalyses at least two reactions: 1) 3' processing, and 2)strand ... belongs to a family of polynucleotidyl transferases/esterases, comprising transposases, RNAses H, and the Argonaut RNAse associated with Dicer (involved in the gene-silencing pathway) [1,6]. These...
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