... intact.In contrast, the inhibitory effect of intrathecal IL-1β on wind-upactivity in propentofylline-treated rats is probably the result of a direct inhibitory effect of the cytokine on dorsal ... neurons of the hypothalamus, whileboth inhibitory and excitatory effects of IL-1β have beenobserved on neocortical neurons [32]. Rapid (minutes) inhibi-tory effects of IL-1β on firing rate of ... Hector Burgos3 and Claudio Laurido11Laboratory of Neurobiology, Department of Biology, Faculty of Chemistry and Biology, University of Santiago of Chile, Ave. Libertador B. O'Higgins 3363,...