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Báo cáo y học: "HIV-1 prevalence and factors associated with infection in the conflict-affected region of North Uganda" pptx

Báo cáo y học:

Báo cáo y học: "HIV-1 prevalence and factors associated with infection in the conflict-affected region of North Uganda" pptx

... of increasing the availa-ble information on the HIV-1 epidemic in northernUganda and identifying the socio-demographic factors associated with HIV-1 infection in this conflict-affected region. Materials ... Sanità" (the National Insti-tute of Health of Italy) and AVSI, in collaboration and with the approval of the STD/AIDS Control Programme of the Ugandan Ministry of Health and the hospitals' ... regard to the factors associated with HIV-1 infection, the strength and direction of the associations found in the univariate analysis are consistent with findings from otherstudies conducted in sub-Saharan...
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Báo cáo y học: "Glutamatergic deficits and parvalbumin-containing inhibitory neurons in the prefrontal cortex in schizophrenia" ppt

... furnished by other pyramidal neurons,located both within the PFC and in other cortical areas[10-12]. The integrity of PFC functions therefore dependson the delicate interplay of feedback and feedforwardmechanisms ... Taken together, our finding of reduced NR2A expression in PV neurons may, at least in part, contribute to the reduction in the expression of GAD67 and PV and the decrease in the density of axon ... immunohistochemistry in combi-nation with quantification of axonal boutons afforded usa higher sensitivity in detecting differences in the presentstudy. In the context of our finding, it is interesting to...
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Báo cáo y học: " GM-CSF and IL-2 as adjuvant enhance the immune effect of protein vaccine against foot-and-mouth disease" pot

... showed the highest level of mRNAs of either Th1 or Th2 cytokines.Expression of the cytokines in the groups with singlecytokine co-expressed or mixed with VP1 showed the same level of either Th1 ... short time and the binding of receptor and ligand, therefore, enhancing the antigen-pres enting abil-ity of APC, subsequently enhancing the level of cell and humoral immune response, leading to ... level of DTH was from groups of BoIL-2 and BoGM-CSF.Th1 and Th2 cytokine profile detectedby semi-quantitative RT-PCRCytokinesplayadominantroleinmodulatingimmuneresponse against infection or in...
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Báo cáo y học: " Severe thrombocytosis and anemia associated with celiac disease in a young female patient: a case report" pdf

... biopsy showing aproliferation of mainly megakaryocytic lineage with increased numbers of enlarged, hyperlobated, maturemegakaryocytes. In addition, one has to exclude an under-lying polycythemia ... for binding of erythropoietin and thrombopoietin to c-mpl and the erythropoietin receptor. On the other hand, it has beensuggested that erythropoietin and thrombopoietin cansynergistically stimulate ... cross-reactivity at the level of the throm-bopoietin receptor c-mpl because of the homology of some amino acid sequences of erythropoietin to throm-bopoietin [8]. The clinical course and correlation of...
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Báo cáo y học: "Renal hypoperfusion and impaired endothelium-dependent vasodilation in an animal model of VILI: the role of the peroxynitrite-PARP pathwa" ppt

... exploring the route of PARP inhibition involved in renal hemodynamic during LPS-induced lung injury aggra-vated by MV. We tested the hypothesis that renal bloodflow and endothelial, functional and ... in the kidney of rats with LPS-induced lung injury aggravated byMV, is caused, in part, by activation of PARP by peroxyni-trite. We demonstrated that inhibition of PARP activationby peroxynitrite ... functional and tissue changes in the kidney of rats with lipopolysaccharide (LPS)-induced lung injury aggravated by MV, is caused, in part, by activation of PARP by peroxynitrite.Methods: Anesthetized...
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Báo cáo Y học: Two 1 : 1 binding modes for distamycin in the minor groove of d(GGCCAATTGG) docx

Báo cáo Y học: Two 1 : 1 binding modes for distamycin in the minor groove of d(GGCCAATTGG) docx

... by inaccuratepositioning of the interacting groups. The contact area of the distamycin amidinium end wasinvestigated by evaluating the hydrogen positions and interaction energy terms for the ... formation.DNA–distamycin interactionsDistamycin binds in the minor groove of the centraloctamer. The expected binding site of at least five basepairs makes interactions with GC base pairs inevitable.Both ... describe the interaction of distamycin in the minor groove of the central CAATTGsequence in a 1 : 1 binding mode. The present tight crystalpacking due to the triplet formation is not compatible with...
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Báo cáo y học: " A single site for N-linked glycosylation in the envelope glycoprotein of feline immunodeficiency virus modulates the virus-receptor interaction" ppt

... in favour of either reinstating the N-linked glycosylationsites following infection or suppressing the replication of T271I and Y3 42N bearing variants in vivo.Neither the T271 nor the N34 2Y ... conserved in the majority of fieldstrains of FIV. The location of these mutations, T271I and N34 2Y, is strikingly similar to previously described N-linked glycosylation sites in the Env of SIV and ... capable of by-passing the primary receptor and interacting directly with the co-receptor [11-15]. In these "CD4-independent" strains of virus, the chemokine receptor binding site may be moreexposed...
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Tài liệu Báo cáo Y học: Bivalent cations and amino-acid composition contribute to the thermostability of Bacillus licheniformis xylose isomerase doc

Tài liệu Báo cáo Y học: Bivalent cations and amino-acid composition contribute to the thermostability of Bacillus licheniformis xylose isomerase doc

... between the buffer and the enzyme by preincubating the enzyme–metal mixture at30 8C for 30 min. Remaining activity was measured with glucose as the substrate in the presence of 4 mM CoCl2. The apoenzyme ... Mn2þ-containing enzyme, loss of the metal cofactor could be the limiting step in BLXIinactivation. Higher Eavalues of inactivation for the Co2þ–enzyme and the Mn2þ–enzyme reflect the higher thermalenergy ... glucose and on xylose, the apoenzyme activity was tested on both sugars in the presence of increasing concentrations of each cation (in the chloride form; Fig. 4). In the absence of metal, the apoenzyme...
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Báo cáo Y học: Lipid rafts and little caves Compartmentalized signalling in membrane microdomains pot

Báo cáo Y học: Lipid rafts and little caves Compartmentalized signalling in membrane microdomains pot

... through the GPI-anchored ephrin-A5 in lipidrafts. The ephrin-A5 induced signalling results in increasedtyrosine phosphorylation of several raft proteins and recruitment of the Src family kinase Fyn ... morphology by regulating the activation of b1integrin through Ôinside-outÕ signalling [78]. It is possible thatb1 integrin functions as a transmembrane adaptor proteinby interacting directly with ... of the protein tyrosine kinases p56lck and p60fyn with the glycosyl phosphatidylinositol-anchored proteins Thy-1 and CD48 in rat thymocytes is dependent on the state of cellularactivation. Eur....
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Báo cáo y học: "Fat-Storing Multilocular Cells Expressing CCR5 Increase in the Thymus with Advancing Age: Potential Role for CCR5 Ligands on the Differentiation and Migration of Preadipocytes" pot

... were increased in the thymus with age. Hy-pothesizing that the increased expression of chemokines and the CCR5 receptor may play a role in adipocyte recruitment and/ or differentiation within the ... thymocytes with advancing age lead to a novel con-ceptual point of view concerning the understanding of the process of thymic physiology in aging, where the increase in adipocytes an fat-bearing ... by the age -associated increases in the staining of thymocytes and microenvironmental cells, including the multilocular fat-storing cells. These data suggest that chemokines may influence the...
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