... sodium attenuates the increase in inflammatory
cytokines and preserves organ function in endotoxemic rats
Toshiaki Iba
1
and Taku Miyasho
2
1
Department of Emergency and Disaster Medicine, Juntendo ... many inflammatory factors, including inflammatory
cytokines, through their HS chains [2-5]. Moreover, recent
data indicate that HS and syndecan protect th...
... supported in part by
the Office of Women's Health, FDA. The findings and conclusions in this
article have not been formally disseminated by the Food and Drug Admin-
istration and should ... Zidovudine
(AZT) synergistically inhibited HIV-1 replication in pri-
mary placental macrophages, possibly explaining why
AZT can inhibit maternal fetal transmission in the absen...
... This
study adds to the previous findings by suggesting that DA may
prevent LPS-induced lung injury by inhibiting cytokine and
HMGB1 secretion.
We demonstrated that IL-10 increased following the adminis-
tration ... (Figure
7).
DA inhibits the IKK pathway and modulates NF-
κ
B
Since the NF-κB pathway plays a critical role in the secretion
of cytokines, we measured the quanti...
... whether ANCA are directly involved in the
pathogenesis of WG or are merely an epiphenomenon
[10]. One of the unresolved issues is the inability to
explain the nonrandom, selected organ injury ... defines
the WG vasculitis and the concurrent, seemingly random,
nature of injury within ‘targeted’ organs [18]. Little is
known about the expression and distribution of PR-3 in...
... functions
A summary of Galaxy’s functionality and how Galaxy’s functionality compares to the functionality of two other genomic workbenches, GenePattern and Mobyle.
Galaxy’s novel functionality includes ... histories,
and workflow so that the study can be rerun in its
entirety [22]. To reproduce the analyses performed in
the study, readers can copy the study’s his tories i...
... mucin-type O-glycosylation
in animals [62]. Glycophosphorylation o f the hydroxya-
mino acids threonine and serine may be less prevalent
in D. purpureum owing to the much smaller size of its
glycophosphotransfer ... N-glycosylation.
Cytoplasmic glycome
Whereas glycosylation occurs predominantly in the
secretory compartments, formation of the precursors for
these pathways gener...
... OAO,
JB, and AWH grew and treated the cells and performed the
cytotoxicity assays and immunoassays for virus titer. OAO
provided important conceptual input regarding the cyto-
toxicity assays. GF ... patients against toxicity induced by radiation and chemotherapy. In an earlier study we
briefly reported that the aminothiol WR1065 also inhibits HIV-1 replication in phytoh...
... play an essen-
tial role in reducing the severity of the I/R injury by
inhibiting neutrophil adhesion in postcapillary venules
and by decreasing microvascular constriction [20]. In our
study, ... at the 7 and 14 day reperfusion time-points. I/R
injury of sciatic nerve has been shown to increase proin-
lammatory cytokines which are primarly responsible
demyelinization after...
... manuscript and was involved in data
interpretation. EO was involved in the conception and design of the study.
FLT and VLT were involved in the care of our patient. VP was involved in
histological ... Conse-
quently, NETs can be found in any location of the body,
although the sites most commonly affected are the gas-
trointestinal and bronchopulmonary tracts, rep...
... pseudoaneurysms of the vessels feeding
the gluteal region, including the inferior and superior
gluteal arteries and a persistent sciatic artery [8]. Aneur-
ysms may compress the sciatic nerve, p roducing ... aneurysm of the femoral artery has been
reported in the case of an HIV-infected patient [7]. We
describe a mycotic aneurysm of the inferior gluteal
artery caused by NT...