Báo cáo y học: " Cost-effectiveness analysis of the available strategies for diagnosing malaria in outpatient clinics in Zambia" potx
Báo cáo y học: " Cost-effectiveness analysis of the available strategies for diagnosing malaria in outpatient clinics in Zambia" potx
... AccessResearch Cost-effectiveness analysis of the available strategies for diagnosing malaria in outpatient clinics in ZambiaPascalina Chanda*1, Marianela Castillo-Riquelme2 and Felix Masiye3Address: ... patients treatedby each type of antimalarial. The potential costs of scalingup the most cost effective strategy in the entire district of analysis were based on the already existing structures ... entered and analysed in excel fol-lowing the principles of cost analysis [12,19]. The cost of malaria drugs for treatment was estimated from the unitcost of antimalarials and the number of patients...
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Báo cáo y học: "Genomic analysis of the relationship between gene expression variation and DNA polymorphism in Drosophila simulans" pps
... temperature in the same facility.Virgin flies from each of the seven genotypes were collectedand housed in single sex vials in groups of ten for three days.On the morning of the fourth day, 3 replicates ... introns,levels of polymorphism in the first intron and the combineddata for all introns were examined separately. Divergencealong the D. simulans lineage was also calculated for each of these features.Association ... 6.865). This analysis, however, may be con-founded by the fact that most genes are not statistically signif-icantly different among lines and that inclusion of these genes in the analysis may obscure...
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Báo cáo Y học: Functional analysis of the rat bile salt export pump gene promoter Regulation by bile acids, drugs and endogenous compounds potx
... immediatelyupstream of the TATA box in the p-126 minimalpromoter construct completely abolished the stimulation of luciferase activity by CDCA in HepG2 cells (Fig. 6).Interestingly CDCA reduced the activity of ... activity of the mutant m-126 Luc even below that of the wild-typep-126 Luc. Analysis of the binding affinity of the putativeFXRE site for the orphan nuclear receptor FXRTo characterize the FXRE ... nucleotide+80.Functional analysis of the Bsep promoter in cell linesWe investigated the tissue specificity of the Bsep promo-ter activity by transfecting several nonhepatic cell lineswith the reporter...
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Báo cáo Y học: Structural analysis of the lipopolysaccharide from nontypeable Haemophilus influenzae strain 1003 potx
... amounts of sialylated Hex3 glycoforms were indicated.bMinor amounts of Hex2 and Hex3 glycoforms lacking acetyl groups orcontaining a second glycyl group were indicated.cVery minor amounts of ... 25. Methylation analysis of dephosphory-lated O S-1 showed significantly increasing amounts of terminal Glc and 2-substituted Hep, thereby indicatingphosphorylation of these residues i n the native ... during the hydrolysis byelimination of phosphate or pyrophosphoethanolaminefrom the C-4 position, which causes both the signal splitting of the methylene protons and the ap pearance of severalanomeric...
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Báo cáo y học: "Detailed analysis of the variability of peptidylarginine deiminase type 4 in German patients with rheumatoid arthritis: a case– control study" docx
... demonstrated.IntroductionPeptidylarginine deiminases (EC 3.5.3.15) are enzymesinvolved in the post-translational deimination of protein-boundarginine to citrulline [1]. Five different types of peptidylargininedeiminases ... http://www.kursus.kvl.dk/shares/vetgen/_Popgen/genetik/applets/kitest.htm).ResultsDistribution of PADI4 haplotype combinations The frequencies of the PADI4 haplotype combinations found in our study are presented in Table 1. A detailed description of the variability of exons 2–4 of the ... padi4_96. The approach used therefore allowed a very detailed analysis of this part of the PADI4 gene that was implicated in influenc-ing RA susceptibility. Of these SNPs, the frequencies of padi4_89A→G,...
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Báo cáo y học: " Psychometric analysis of the Self-Harm Inventory using Rasch modelling" ppsx
... related.Conclusion: The recommended cut-off point of five is likely to comprise mild forms of DSH andmay not be indicative of psychopathology in a non-clinical population. Rather it may be moreindicative of ... Pole M: Borderline personalitysymptomology and employment disability: a survey amongoutpatients in an internal medicine clinic. Primary Care Compan-ion Journal of Clinical Psychiatry 2006, 8:153-157.34. ... comparisons.Discussion The aim of this study was to use Rasch analysis to test the internal validity of the Self-Harm Inventory (SHI) scale in a non-clinical population. In terms of the gender differ-ences,...
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Báo cáo y học: "Metagenomic analysis of the turkey gut RNA virus community" doc
... deal about the complex viral com-munity in the turkey gut. Further, a community-basedunderstanding of the viruses in the poultry gut will bean invaluable asset in ongoing studies of the enteric ... and wrote the paper. LLB performed the bioinformatic analyses. MVD prepared the samples and performed the 454pyrosequencing. BES coordinated the bioinformatic analyses andpyrosequencing. LZ provided ... of viruses may playa role in poultry enteric disease. Despite the isolationand characterization of many of these suspect viruses, the etiology of the poultry enteric disease syndromesremains...
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Báo cáo y học: "Sequence analysis of the Epstein-Barr virus (EBV) BRLF1 gene in nasopharyngeal and gastric carcinomas" docx
... carc inoma patients as well as the healthy individuals gave an informed consent for the studyandthestudywasapprovedbytheMedicalEthics Committee at the Medical College of QingdaoUniversity, China.DNAs ... were sequenced by means of aPrism ready reaction Dyedeoxy terminator cycle sequen-cing kit (Applied Biosystems, Foster, USA).Data analysis ThesequencedatawerecheckedforanyhomologyinBLAST (N ational ... able information for choosing target epitopes for control of EBV lyticactivation.Conclusions In conclusion, we have identified 5 distinct subtypes of BRLF1inNorthernChineseEBVisolatesinmultipleclinical...
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Báo cáo y học: "Mutagenesis analysis of the zinc-finger antiviral protein" ppt
... that the integ-rity of the overall structure of ZAP may be important for the protein to bind the target RNA and that there may bemultiple RNA binding sites. Alternatively, these aminoacids may ... protein (ZAP) specifically inhibits the replication of certain viruses, including murine leukemia virus (MLV), by preventing the accumulation of viral mRNA in the cytoplasm. ZAP directly binds ... very modest. The interactions of all the mutants with the exosome were comparable to wild type ZAP.Conclusions: The integrity of the very N-terminal domain and the first and second zinc-finger...
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Báo cáo y học: "Theoretical analysis of the mechanisms of a gender differentiation in the propensity for orthostatic intolerance after spaceflight" docx
... women due to their inher-ent lower center of gravity and proportionately larger mass in the lower extremities.Examining the theoretical consistency of the hypothesis in the context of the currentconsidered ... 7:8http://www.tbiomed.com/content/7/1/8Page 5 of 8stress on two identical physiologic systems with only a variance in their longitudinal center of gravity.Computer Systems Analysis of the Hypothesis The hypothesis was examined through ... systems analysis approach to the problem was used to integrate many of the experimental findings in to a morecomprehensive theory of understanding [14]. The analysis suggested that changes in the...
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