Báo cáo y học: "An anti-inflammatory role for tranexamic acid in cardiac surgery" docx
Báo cáo y học: "An anti-inflammatory role for tranexamic acid in cardiac surgery" docx
... cardiopulmonarybypass: participation of interleukin 8 and 6 in reperfusioninjury. Can J Anaesth 1993, 40:1016-1021.5. Laffey JG, Boylan JF, Cheng DC: The systemic inflammatoryresponse to cardiac ... attenuate inflammation reveals a glimpse ofhow the fibrinolytic and pro-inflammatory responses areinterlinked. The interplay of other major pro- and anti-inflammatory mediators is worthy of further ... ML: Tranexamic acid attenuates inflammatory response in car-diopulmonary bypass surgery through blockade of fibrinoly-sis: a case control study followed by a randomizeddouble-blind controlled trial....
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Báo cáo Y học: An alternative model for photosystem II/light harvesting complex II in grana membranes based on cryo-electron microscopy studies pptx
... combined factors may explain whyprevious studies did not readily identify two planes ofdensity. Negatively stained PSII/LHCII c rystals in spinachgrana [14] do d isplay some small domains ... AÊ2wasemployedinthestudy by Rhee & coworkers [11], suggesting that fading isnot signi®cantly steeper for the in situ PSII crystals we havestudied. The image processing approach employed here for small ... averaging of cryo-electron microscopy data for several small crystalline areasis practical and results in structural data equivalent i nquality to that obtained from much larger single crystallinearrays.In...
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Báo cáo y học: "A proinflammatory role for Fas in joints of mice with collagen-induced arthritis" docx
... inflammation/joint destruction in DBA-lpr/lpr mice in spite of the same clinical score as that of controlmice.The proinflammatory cytokines including TNF-α and IL-6have been intensively investigated ... disease by destroying target tissues throughinduction of apoptosis of chondrocytes [33]. Alternatively,Fas could contribute to synovial hyperplasia by inducingproliferation of Fas-expressing synovial ... investigated for their role in thepathogenesis of CIA. It is well known that they play a crucial role in the destruction of joints in CIA [37,42-44]. TNF-αinduces synovial fibroblasts to express cytokines...
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Báo cáo y học: "An optimization framework for unsupervised identification of rare copy number variation from SNP array data." doc
... Bird-suite platform [17]. QuantiSNP [26] is an analytical tool for the analysis of copy number variation using whole genomeSNP genotyping data. It was originally developed for Illuminaarrays, but ... term. More specifically, in the absence of copy number variation, is 2.0 for an AAgenotype, for an AB genotype, and 0 for a BB genotype.The fitting procedure yields estimates for the model parameters.We ... raw copy extraction, and CNV calling.Normalization is performed on the raw array intensity data in order to be able to compare these values fairly, thereby takinginto account differences in overall...
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Báo cáo y học: "An alternative methodology for the prediction of adherence to anti HIV treatment" ppt
... showedthat life expectancy at age 20 years had increased by over13 years since the introduction of combination antiretro-viral therapy and currently life expectancy of HIV patientsat age 20 ... Study Group3Address: 1School of Life Sciences, Kingston University, Penrhyn Road, Kingston-upon-Thames. KT1 2EE, UK, 2Faculty of Computing, Information Systems and Mathematics, Kingston ... Technology LTD (Haifa, Israel), Max Planck-Institut für Informatik (Max-Planck-Institute for Informatics, Saarbrücken, Germany), Központi Fizikai Kutató Intézet – Részecske-és Magfizikai Kutatóintézet...
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Báo cáo y học: "Medicinal plants used for traditional veterinary in the Sierras de Córdoba (Argentina): An ethnobotanical comparison with human medicinal uses" ppt
... potentiallytoxic plants in Argentina [43], only a dozen werereported by the local people and documented in thispaper. The plants were categorized by the informersaccording to the frequency of intoxication ... 2 The medicinal plant uses in traditional veterinary medicin e of the Sierras de C?ó?rdoba. (*) Veterinary medic-inal use coincide with human medicinal use (Continued)wounds andinjuries(*)leaves/decoction/washesocular ... analysisFieldwork was carried out as part of an ethnobotanicregional study in which 64 informants (35 women and29 men) were interviewed about medicinal plants used in veterinary me dicine during...
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Báo cáo y học: "An alternate solution for the treatment of ascending aortic aneurysms: the wrapping technique" pps
... aortic surgery, we are glad to reportthat no incidents of the kind were observed. In conclusion, the Dacron wrapping technique can bean alternative solution for ascending aortic aneurysmswithout ... aortic aneurysmswithout dissecting elements in cases of severely morbidpatients who are unwilling to undergo major aortic sur-gery due to the significantly increased perioperative risk.We ... aortic surgery.Conflicts of interestThe authors declare that there are no conflicts of interest.Author details1Department of Cardiovascular and Thoracic Surgery, University of Thessaly,Larissa,...
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Báo cáo y học: "A crucial role for tumor necrosis factor receptor 1 in synovial lining cells and the reticuloendothelial system in mediating experimental arthritis" pps
... paraformaldehyde for 4 days. After decalcification in 5% formic acid, speci-mens were processed for paraffin embedding. Tissue sec-tions (7 μm) were stained with hematoxylin and eosin(cell influx) ... centrifuged for 5 minutes at 1,000 g. Murine IL-1β, IL-6, and TNFαlevels were determined using the Luminex multianalytetechnology and the BioPlex system in combination withBioPlex Mouse Cytokine Assays ... revealed, in line withthe study of Armaka and colleagues [10], a dominant role of TNFR1-mediated signaling in SLCs in joint inflamma-tion.Remarkably, we found that TNFR1 silencing in kneejoints...
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Báo cáo y học: "A Functional Role for ADAM10 in Human Immunodeficiency Virus Type-1 Replication" pptx
... metalloproteasedomain, it also c ontains a disintegrin domain, an EGF-like domain, a cysteine-rich domain, a transmembranedomain, and a cytoplasmic domain [13]. ADAM10 isrequired in NOTCH signaling during ... alloprotease domain po tentiallyresponsible for this increase was further investigated.ADAM10 E384A plasmid contains a single inactivatingpoint mutation in the metalloprotease doma in renderingthe ... antibody(R&D Systems, Minneapolis, MN) or an IgG1 isotypecontrol (Southern Biotech, Birmingham, AL), followedby incubation with a phycoerythrin-conjugated rabbitanti-mouse secondary antibody...
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Báo cáo y học: "An annotation infrastructure for the analysis and interpretation of Affymetrix exon array data" pot
... feature density on thesearrays is very high, resulting in a relatively large number ofprobes capable of hybridizing in more than one place. Many-to-many relationships can be further refined at the ... support fine-grained analysis of exon array data.</p>AbstractAffymetrix exon arrays contain probesets intended to target every known and predicted exon in the entire genome, posing significant ... and interpretsuch data for each individual gene of interest. Second, if anal-ysis is to be pursued systematically (rather than simply byselecting genes based on prior knowledge), techniques for global,...
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