Báo cáo y học: " Optimization of the doxycycline-dependent simian immunodeficiency virus through in vitro evolution" docx
Báo cáo y học: "Characterization of a new simian immunodeficiency virus strain in a naturally infected Pan troglodytes troglodytes " ppt
... thank the Cameroon Ministry of Scientific Research andInnovation, the Ministry of Health and the Ministry of Forestry and Wildlife,which provided the necessary permits for this work. We thank the ... SIVcpzinfection resembles that of HIV-1 in humans. Given the poor health status of the animal described in this study, the administration of antiretroviral therapy may benecessary in the near ... S,Paiardini M, Else J, Silvestri G: A five-year longitudinal analysis of sootymangabeys naturally infected with simian immunodeficiency virus reveals a slow but progressive decline in CD4+ T-cell...
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Báo cáo y học: " Optimization of the doxycycline-dependent simian immunodeficiency virus through in vitro evolution" docx
... corresponding tet-operator(tetO) DNA binding sites were inserted into the LTR pro-moter. Since the rtTA protein can only bind tetO and acti-vate transcription in the presence of doxycycline (dox),HIV-rtTA ... repli-cates exclusively in the presence of dox. As the TAR muta-tions and tetO elements were introduced in both the 5'and 3' LTR, they are stably maintained in the viral prog-eny.We demonstrated ... with doxycycline-dependent HIV-1. Virol2004, 328:1-6.24. Das AT, Baldwin CE, Vink M, Berkhout B: Improving the safety of a conditional-live human immunodeficiency virus type 1 vac-cine by controlling...
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Báo cáo Y học: Effect of the disease-causing mutations identified in human ribonuclease (RNase) H2 on the activities and stabilities of yeast RNase H2 and archaeal RNase HII pot
... the protein withoutseriously affecting the substrate binding affinity.Binding analyses using BIAcore systemTo examine whether the mutation of Gly10 to Leu orPro affects the substrate binding ... models, in which the oxygen atoms are shown in red. The side chain of Tyr170 is alsoillustrated by a blue stick model. The main chain of Gly10 is shown in red. N, N-terminus. The Protein Data ... affecting complex stability. By con-trast, neither the mutation in Sc-Rnh2Bp nor that in Sc-Rnh2Cp seriously affects enzymatic activity. The role of the conserved glycine residue in the catalyticsubunit...
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Báo cáo y học: "Osteoradionecrosis of the cervical spine presenting with quadriplegia in a patient previously treated with radiotherapy for laryngeal cancer: a case report" docx
... but cases of avascular necrosis of the cervical spine following radiotherapy to the larynxappear to be extremely rare. A review of the English language literature has shown only one other casewhere ... of the cervical spine 20 years after radiotherapy treatment for a T1aN0M0laryngeal carcinoma resulting in quadriplegia.Conclusions: Radiotherapy carries a long-term risk of complications, including ... Edition.ConsentWritten informed consent was obtained from the patientfor publication of this case report and any accompanyingimages. A copy of the written consent is available forreview by the Editor -in- Chief of...
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Báo cáo y học: " Deletion of the meq gene significantly decreases immunosuppression in chickens caused by pathogenic marek’s disease virus" pptx
... pp38 isinvolved in early cytolytic infection of lymphocytes, butnot the induction of tumors [11]. Recently studiesshowed that the mechanism of attenuation of MDVdoes not involve the 132 bp repeat ... play an impor-tant role in both protecting against MDV infection andtumor repression in chickens [23,24]. These findingssuggest that the Meq gene may be involved in T cellimmunosuppression in ... effects. Theseresults indicated that the Meq gene played an importantrole not only in tumor formation but also in inducingimmunosuppressive affects in MDV-infected chickens. The analysis of T...
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Báo cáo y học: " Characterization of the bronchodilatory dose response to indacaterol in patients with chronic obstructive pulmonary disease using modelbased approaches" ppt
... Doses of 150 μg or higher provide sustained bronchodilationthat is largely independent of disease severity.Finally, it is instructive to place the findings of thisanalysis in the context of the ... each of the comparators included in this analysis. The most striking feature of the plot isthat the response to indacaterol at the plateau exceeds the response of all comparators. In other words, ... marker of disease severity, was the key covariate. The impact of baseline FEV1onthedoseresponseintheabsence o f any model-based interpretation is shown in figure 6. The figure shows the individual...
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Báo cáo y học: " Effect of chloroquine on reducing HIV-1 replication in vitro and the DC-SIGN mediated transfer of virus to CD4+ T-lymphocytes" pdf
... alteration of the PNG sequence of gp120 may alter its binding to DC-SIGN, or alternatively the glycosylation machinery of the cell can influence the interaction of the virus with DC-SIGN. To test the ... inhibition of infection of CD4+ T-lym-phocytes. This may be explained by the fact that in ourexperiments we compensate for the presence of CQ in the produced virus stock, thereby eliminating the ... performed in triplicate. G) Determination of TCID50/ml values of pas-saged viruses in the absence or presence of CQ. Viral infectivity of the viruses passaged in the absence or presence of CQ (days...
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Báo cáo y học: "Mechanism of the chromosome-induced polar body extrusion in mouse eggs" potx
... chromosomes inducecortical actin and myosin II assembly into a distinctactincapsurroundedbyamyosinIIringintheMIIeggs [6]. Interestingly, sperm chromatin incorporation atfertilization or m icroinjection ... signals.Microinjection of DNA beads revealed sequentialassembly of cortical actomyosin cap and myosin II ringWe further fo llowed up the kinetics of actin and myosinII assemblies that are induced by the ... likely by activating myosin IIcontractility [16]. Consistently, inhibition of myosin IIcontraction by using bl ebbistatin [17] or myo sin lightchain kinase by ML-7 [18] all blocked the cortical...
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Báo cáo y học: "Comparison of the oxidative phosphorylation (OXPHOS) nuclear genes in the genomes of Drosophila melanogaster, Drosophila pseudoobscura and Anopheles gambiae" docx
... surely allow abetter understanding of the evolutionary history of a set of genes that control a basic biological function, and also offerinteresting insights into the mechanisms of their coordinatedexpression. ... coordinates the expression of the whole set of energy-producing genes in Drosophila [57]. The comparative analysis of the 78 OXPHOS genes in the three dipteran species shows a high level of amino-acidsequence ... distribu-tion, ranging from hundreds to thousands of base-pairs [30-32]. Of the introns that interrupt the coding sequence in the 78OXPHOS genes investigated in the present study, 88 (64.7%) of 136 in D....
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Tài liệu Báo cáo Y học: Inhibition of nuclear pre-mRNA splicing by antibiotics in vitro pot
... [31].RESULTSErythromycin, Cl-tetracycline and streptomycin inhibitnuclear splicing in vitro The effects of eight different antibiotics (the aminoglycoside,kanamycin, the a minocyclitol glycoside, streptomycin, ... with the binding o f the functional sub strate.Type-II binding sites are the central metal ion-binding pock-ets i n the catalytic cores of ribozymes. In type-II bindingsites the aminoglycosides ... splicing apparatus. The inhibitoryeffect of erythromycin and Cl-tetracycline were not allevi-ated by Mg2+(Fig. 3).Kinetic analyses using increasing concentrations of erythromycin, Cl-tetracycline...
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Từ khóa: Báo cáo thực tập tại nhà thuốc tại Thành phố Hồ Chí Minh năm 2018Nghiên cứu tổ chức pha chế, đánh giá chất lượng thuốc tiêm truyền trong điều kiện dã ngoạiMột số giải pháp nâng cao chất lượng streaming thích ứng video trên nền giao thức HTTPNghiên cứu vật liệu biến hóa (metamaterials) hấp thụ sóng điện tử ở vùng tần số THzđề thi thử THPTQG 2019 toán THPT chuyên thái bình lần 2 có lời giảiGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitĐỒ ÁN NGHIÊN CỨU CÔNG NGHỆ KẾT NỐI VÔ TUYẾN CỰ LY XA, CÔNG SUẤT THẤP LPWANĐỒ ÁN NGHIÊN CỨU CÔNG NGHỆ KẾT NỐI VÔ TUYẾN CỰ LY XA, CÔNG SUẤT THẤP LPWANNGHIÊN CỨU CÔNG NGHỆ KẾT NỐI VÔ TUYẾN CỰ LY XA, CÔNG SUẤT THẤP LPWAN SLIDEPhát triển mạng lưới kinh doanh nước sạch tại công ty TNHH một thành viên kinh doanh nước sạch quảng ninhNghiên cứu, xây dựng phần mềm smartscan và ứng dụng trong bảo vệ mạng máy tính chuyên dùngNghiên cứu tổng hợp các oxit hỗn hợp kích thƣớc nanomet ce 0 75 zr0 25o2 , ce 0 5 zr0 5o2 và khảo sát hoạt tính quang xúc tác của chúngSở hữu ruộng đất và kinh tế nông nghiệp châu ôn (lạng sơn) nửa đầu thế kỷ XIXTổ chức và hoạt động của Phòng Tư pháp từ thực tiễn tỉnh Phú Thọ (Luận văn thạc sĩ)Tranh tụng tại phiên tòa hình sự sơ thẩm theo pháp luật tố tụng hình sự Việt Nam từ thực tiễn xét xử của các Tòa án quân sự Quân khu (Luận văn thạc sĩ)Giáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtGiáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtChiến lược marketing tại ngân hàng Agribank chi nhánh Sài Gòn từ 2013-2015TÁI CHẾ NHỰA VÀ QUẢN LÝ CHẤT THẢI Ở HOA KỲ